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المؤلفAl Shanableh, Yasemin
المؤلفHussein, Yehia Y.
المؤلفWali, Abdul Haseeb Said
المؤلفAl-Mohannadi, Maryam
المؤلفAljalham, Budoor
المؤلفNurulhoque, Hamnah
المؤلفRobelah, Fahad
المؤلفAl-mansoori, Areej
المؤلفZughaier, Susu
تاريخ الإتاحة2021-10-18T08:15:41Z
تاريخ النشر2021
اسم المنشورQatar University Annual Research an Exhibition 2021 (quarfe)
الاقتباسAl-Shanableh Y., Hussein Y. Y., Wali A. H. S., Al-Mohannadi M., Aljalham B., Nurulhoque H., Robelah F., Al-mansoori A., Zughaier S., "Prevalence of Asymptomatic Hyperuricemia and its Association with Prediabetes, Dyslipidemia and Subclinical Inflammation Markers among Young Healthy Adults in Qatar", Qatar University Annual Research Forum and Exhibition (QUARFE 2021), Doha, 20 October 2021, https://doi.org/10.29117/quarfe.2021.0139
معرّف المصادر الموحدhttps://doi.org/10.29117/quarfe.2021.0139
معرّف المصادر الموحدhttp://hdl.handle.net/10576/24424
الملخصAim: To investigate the prevalence of asymptomatic hyperuricemia in Qatar and to examine its association with changes in markers of dyslipidemia, prediabetes and subclinical inflammation. Methods: A cross-sectional study of young adult participants aged 18 - 40 years old devoid of comorbidities. Exposure was defined as uric acid level, and outcomes were defined as levels of different blood markers. De-identified data were collected from Qatar BioBank. T-tests, correlation tests and multiple linear regression were all used to investigate the effects of hyperuricemia on blood markers. Statistical analyses were conducted using STATA 16. Results: The prevalence of asymptomatic hyperuricemia is 21.2% among young adults in Qatar. Differences between hyperuricemic and normouricemic groups were observed using multiple linear regression analysis and found to be statistically and clinically significant after adjusting for age, gender, BMI, smoking and exercise. Significant associations were found between uric acid level and HDL-c p = 0.019 (correlation coefficient -0.07 (95% CI [-0.14, -0.01]); c-peptide p = 0.018 (correlation coefficient 0.38 (95% CI [0.06, 0.69]) and monocyte to HDL ration (MHR) p = 0.026 (correlation coefficient 0.47 (95% CI [0.06, 0.89]). Conclusion: Asymptomatic hyperuricemia is prevalent among young adults and associated with markers of prediabetes, dyslipidemia, and subclinical inflammation.
اللغةen
الناشرQatar University Press
الموضوعUric acid
asymptomatic hyperuricemia
subclinical inflammation
prediabetes
Qatar Biobank
العنوانPrevalence of Asymptomatic Hyperuricemia and its Association with Prediabetes, Dyslipidemia and Subclinical Inflammation Markers among Young Healthy Adults in Qatar
النوعPoster
dc.accessType Open Access


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