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AuthorKumari, Suman
AuthorTiyyagura, Hanuma Reddy
AuthorPottathara, Yasir Beeran
AuthorSadasivuni, Kishor Kumar
AuthorPonnamma, Deepalekshmi
AuthorDouglas, Timothy E.L.
AuthorSkirtach, Andre G.
AuthorMohan, M.K.
Available date2022-03-23T06:35:48Z
Publication Date2021
Publication NameCarbohydrate Polymers
ResourceScopus
Identifierhttp://dx.doi.org/10.1016/j.carbpol.2020.117487
URIhttp://hdl.handle.net/10576/28589
AbstractMetallic implants have dominated the biomedical implant industries for the past century for load-bearing applications, while the polymeric implants have shown great promise for tissue engineering applications. The surface properties of such implants are critical as the interaction of implant surfaces, and the body tissues may lead to unfavourable reactions. Desired implant properties are biocompatibility, corrosion resistance, and antibacterial activity. A polymer coating is an efficient and economical way to produce such surfaces. A lot of research has been carried out on chitosan (CS)-modified metallic and polymer scaffolds in the last decade. Different methods such as electrophoretic deposition, sol-gel methods, dip coating and spin coating, electrospinning, etc. have been utilized to produce CS coatings. However, a systematic review of chitosan coatings on scaffolds focussing on widely employed techniques is lacking. This review surveys literature concerning the current status of orthopaedic applications of CS for the purpose of coatings. In this review, the various preparation methods of coating, and the role of the surface functionalities in determining the efficiency of coatings are discussed. Effect of nanoparticle additions on the polymeric interfaces and in regulating the properties of surface coatings are also investigated in detail.
SponsorThis publication was made possible by Erasmus Mundus Programme Lot 5 (Asia), IMPAKT (International Mobility Programme for Academic and Knowledge Transfer) Project and supported by Qatar university Internal Grant No. IRCC-2020-013 . A.G.S. acknowledges support of FWO Vlaanderen ( G043219N , I002620N ) and BOF UGent ( IOP 01/O3618 ). The findings achieved herein are solely the responsibility of the authors.
Languageen
PublisherElsevier Ltd
SubjectBiomaterials
Chitosan
Electrophoretic deposition
Titanium alloys
TitleSurface functionalization of chitosan as a coating material for orthopaedic applications: A comprehensive review
TypeArticle Review
Volume Number255
dc.accessType Abstract Only


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