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المؤلفDonadu, Matthew G.
المؤلفChowdhury, Shazeda H.
المؤلفElgamal, Mahmoud
المؤلفUsai, Donatella
المؤلفZanetti, Stefania
المؤلفZughaier, Susu M.
تاريخ الإتاحة2022-03-24T05:34:01Z
تاريخ النشر2022
اسم المنشورJournal of Emergency Medicine, Trauma and Acute Care
المصدرqscience
الاقتباسDonadu MG, Chowdhury SH, Elgamal M, Usai D, Zanetti S, Zughaier SM. Antibacterial activity of Myrtus communis L. and Melaleuca leucadendron var. cajaputi essential oils against antibiotic-resistant bacterial strains, Journal of Emergency Medicine, Trauma & Acute Care 2022:36 http://dx.doi.org/10.5339/jemtac.2022.qhc.36
الرقم المعياري الدولي للكتاب1999-7086
الرقم المعياري الدولي للكتاب1999-7094
معرّف المصادر الموحدhttps://doi.org/10.5339/jemtac.2022.qhc.36
معرّف المصادر الموحدhttp://hdl.handle.net/10576/28979
الملخصBackground: Antimicrobial resistance (AMR) is a global threat to public health. There is a dire need for new antibiotics as AMR threatens our last-resort antibiotics efficacy. 1,2 Myrtle plants have been used in folk medicine for centuries. Essential oils from these plants demonstrated therapeutics effects. This study aims to examine the antibacterial activity of essential oils extracted from Myrtus communis L and Melaleuca leucadendron against clinically relevant bacterial pathogens. 3 Methods: Bacterial growth curves and bactericidal assays were performed on antibiotic-sensitive Staphylococcus aureus (SA) and antibiotic low and high resistant Methicillin-resistant Staphylococcus aureus (MRSA) strains; sensitive and resistant Klebsiella pneumoniae strains (KPS and KPR). Minimum bactericidal concentration (MBC) was performed on 4 strains of colistin sensitive E. coli and 4 colistin resistant E. coli strains. Results: Myrtle essential oils demonstrated a dose-dependent antibacterial activity against all tested strains and inhibited growth even after 24 hours. The tested oils dilutions ranged from 6.15 ?l/ml up to 50 ?l/ml and inhibited bacterial growth of both antibiotic sensitive and resistant strains of SA, MRSA (Figure 1), and Klebsiella. Further, the incubation of colistin sensitive and colistin-resistant E. coli strains with 50 ?l/ml of Myrtle oil for one hour inhibited the growth of all tested strains. The viability of bacteria was tested by spotting on agar plates and further incubation overnight. The data suggest that Myrtle essential oils can effectively kill bacterial pathogens. Conclusion: Essential oils from Myrtus communis L. and Melaleuca leucadendron var. cajaputi possess potent antibacterial activity against antibiotic sensitive and resistant bacterial pathogens. There is a potential for utilizing these antibacterial oils as topical treatment of wound infections.
اللغةen
الناشرHamad bin Khalifa University Press (HBKU Press)
الموضوعAntimicrobial resistance
Antibacterial activity
Staphylococcus aureus
Klebsiella pneumonia
Myrtle essential
العنوانAntibacterial activity of Myrtus communis L. and Melaleuca leucadendron var. cajaputi essential oils against antibiotic-resistant bacterial strains
النوعArticle
رقم العدد1
رقم المجلد2022
dc.accessType Open Access


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