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AuthorDonadu, Matthew G.
AuthorChowdhury, Shazeda H.
AuthorElgamal, Mahmoud
AuthorUsai, Donatella
AuthorZanetti, Stefania
AuthorZughaier, Susu M.
Available date2022-03-24T05:34:01Z
Publication Date2022
Publication NameJournal of Emergency Medicine, Trauma and Acute Care
Resourceqscience
CitationDonadu MG, Chowdhury SH, Elgamal M, Usai D, Zanetti S, Zughaier SM. Antibacterial activity of Myrtus communis L. and Melaleuca leucadendron var. cajaputi essential oils against antibiotic-resistant bacterial strains, Journal of Emergency Medicine, Trauma & Acute Care 2022:36 http://dx.doi.org/10.5339/jemtac.2022.qhc.36
ISSN1999-7086
ISSN1999-7094
URIhttps://doi.org/10.5339/jemtac.2022.qhc.36
URIhttp://hdl.handle.net/10576/28979
AbstractBackground: Antimicrobial resistance (AMR) is a global threat to public health. There is a dire need for new antibiotics as AMR threatens our last-resort antibiotics efficacy. 1,2 Myrtle plants have been used in folk medicine for centuries. Essential oils from these plants demonstrated therapeutics effects. This study aims to examine the antibacterial activity of essential oils extracted from Myrtus communis L and Melaleuca leucadendron against clinically relevant bacterial pathogens. 3 Methods: Bacterial growth curves and bactericidal assays were performed on antibiotic-sensitive Staphylococcus aureus (SA) and antibiotic low and high resistant Methicillin-resistant Staphylococcus aureus (MRSA) strains; sensitive and resistant Klebsiella pneumoniae strains (KPS and KPR). Minimum bactericidal concentration (MBC) was performed on 4 strains of colistin sensitive E. coli and 4 colistin resistant E. coli strains. Results: Myrtle essential oils demonstrated a dose-dependent antibacterial activity against all tested strains and inhibited growth even after 24 hours. The tested oils dilutions ranged from 6.15 ?l/ml up to 50 ?l/ml and inhibited bacterial growth of both antibiotic sensitive and resistant strains of SA, MRSA (Figure 1), and Klebsiella. Further, the incubation of colistin sensitive and colistin-resistant E. coli strains with 50 ?l/ml of Myrtle oil for one hour inhibited the growth of all tested strains. The viability of bacteria was tested by spotting on agar plates and further incubation overnight. The data suggest that Myrtle essential oils can effectively kill bacterial pathogens. Conclusion: Essential oils from Myrtus communis L. and Melaleuca leucadendron var. cajaputi possess potent antibacterial activity against antibiotic sensitive and resistant bacterial pathogens. There is a potential for utilizing these antibacterial oils as topical treatment of wound infections.
Languageen
PublisherHamad bin Khalifa University Press (HBKU Press)
SubjectAntimicrobial resistance
Antibacterial activity
Staphylococcus aureus
Klebsiella pneumonia
Myrtle essential
TitleAntibacterial activity of Myrtus communis L. and Melaleuca leucadendron var. cajaputi essential oils against antibiotic-resistant bacterial strains
TypeArticle
Issue Number1
Volume Number2022
dc.accessType Open Access


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