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المؤلفTamimi, Faleh
المؤلفAltigani, Shiraz
المؤلفSanz, Mariano
تاريخ الإتاحة2022-05-16T04:25:56Z
تاريخ النشر2022-06-01
اسم المنشورPeriodontology 2000
المعرّفhttp://dx.doi.org/10.1111/prd.12434
الاقتباسTamimi, F, Altigani, S, Sanz, M. Periodontitis and coronavirus disease 2019. Periodontol 2000. 2022; 98: 207– 214. doi:10.1111/prd.12434
الرقم المعياري الدولي للكتاب09066713
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85125592119&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/30899
الملخصThe coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 is usually a mild condition; however, in some cases it can result in severe sickness and even death. Thus, understanding the reasons behind these grave outcomes is of great importance. Coronavirus disease 2019 and periodontitis share some intriguing characteristics. They can both lead to systemic inflammation and alterations of coagulation pathways, and both share confounding factors, such as diabetes, hypertension, and obesity. Accordingly, a possible association between these conditions has been hypothesized in the literature. The objective of this review was to evaluate the scientific evidence linking these diseases and the possible underlying mechanisms. Evidence has shown that coronavirus disease 2019 presents oral manifestations and can even affect periodontal tissues. Moreover, some studies have shown a possible association between coronavirus disease 2019 severity and the presence of periodontitis. Current evidence suggests that this association could be explained through the direct role of periodontal bacteria in aggravating lung infections, as well as through the indirect effect of periodontitis in inducing systemic inflammation and priming of the immune system to an exacerbated reaction to severe acute respiratory syndrome coronavirus 2 infection. Future research is needed to confirm these observations and explore the possible role that periodontal care might play in the coronavirus disease 2019 pandemic.
راعي المشروعThe authors acknowledge support from the Hamad Medical Corporation Business Intelligence Center.
اللغةen
الناشرWiley
الموضوعCardiovascular diseases
COVID-19
Diabetes
Periodontitis
SARS-CoV-2
العنوانPeriodontitis and coronavirus disease 2019
النوعArticle Review
الصفحات207-214
رقم العدد1
رقم المجلد89
ESSN1600-0757
dc.accessType Open Access


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