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AuthorTamimi, Faleh
AuthorAltigani, Shiraz
AuthorSanz, Mariano
Available date2022-05-16T04:25:56Z
Publication Date2022-06-01
Publication NamePeriodontology 2000
Identifierhttp://dx.doi.org/10.1111/prd.12434
CitationTamimi, F, Altigani, S, Sanz, M. Periodontitis and coronavirus disease 2019. Periodontol 2000. 2022; 98: 207– 214. doi:10.1111/prd.12434
ISSN09066713
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85125592119&origin=inward
URIhttp://hdl.handle.net/10576/30899
AbstractThe coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 is usually a mild condition; however, in some cases it can result in severe sickness and even death. Thus, understanding the reasons behind these grave outcomes is of great importance. Coronavirus disease 2019 and periodontitis share some intriguing characteristics. They can both lead to systemic inflammation and alterations of coagulation pathways, and both share confounding factors, such as diabetes, hypertension, and obesity. Accordingly, a possible association between these conditions has been hypothesized in the literature. The objective of this review was to evaluate the scientific evidence linking these diseases and the possible underlying mechanisms. Evidence has shown that coronavirus disease 2019 presents oral manifestations and can even affect periodontal tissues. Moreover, some studies have shown a possible association between coronavirus disease 2019 severity and the presence of periodontitis. Current evidence suggests that this association could be explained through the direct role of periodontal bacteria in aggravating lung infections, as well as through the indirect effect of periodontitis in inducing systemic inflammation and priming of the immune system to an exacerbated reaction to severe acute respiratory syndrome coronavirus 2 infection. Future research is needed to confirm these observations and explore the possible role that periodontal care might play in the coronavirus disease 2019 pandemic.
SponsorThe authors acknowledge support from the Hamad Medical Corporation Business Intelligence Center.
Languageen
PublisherWiley
SubjectCardiovascular diseases
COVID-19
Diabetes
Periodontitis
SARS-CoV-2
TitlePeriodontitis and coronavirus disease 2019
TypeArticle Review
Pagination207-214
Issue Number1
Volume Number89
ESSN1600-0757
dc.accessType Open Access


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