Medicine Research
Recent Submissions
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Protocol of the Nutritional, Psychosocial, and Environmental Determinants of Neurodevelopment and Child Mental Health (COINCIDE) study
( F1000 Research Limited , 2024 , Article)Background: Over 250 million children are developing sub-optimally due to their exposure to early life adversities. While previous studies have examined the independent effects of nutritional status, psychosocial adversities, ... -
MSEUnet: Refined Intima-media segmentation of the carotid artery based on a multi-scale approach using patch-wise dice loss
( Elsevier , 2025 , Article)Carotid artery stenosis risk stratification is one of the most sought-after methods for diagnosing the chances of stroke. There is an inherent requirement to identify the risk before its onset through techniques such as ... -
A Decade of Discovery of Huntington's Disease Biomarkers: A Comprehensive Review of its Established and Emerging Bi-omarkers
( preprints , 2024 , Article Review)Neurodegenerative disorders (NDs) lead to progressive neuronal loss in various brain regions and are a significant public health concern, with NDs expected to become the second-leading cause of death globally within the ... -
Advances in Huntington’s Disease Biomarkers: A 10-Year Bibliometric Analysis and a Comprehensive Review
( MDPI , 2025 , Article Review)Neurodegenerative disorders (NDs) cause progressive neuronal loss and are a significant public health concern, with NDs projected to become the second leading global cause of death within two decades. Huntington’s disease ... -
Lifetime prevalence, risk, and treatment of mood and anxiety disorders in Qatar's national mental health study
( John Wiley and Sons Ltd , 2024 , Article)Objectives: To estimate lifetime prevalence, risk, and treatment for mental disorders and their correlates in Qatar's general population for the first time. Methods: We conducted a national phone survey of 5,195 Qatari and ... -
Ṯābit Ibn Qurrah’s contributions to toxicology
( Springer , 2024 , Article Review)Mankind has been familiar with poisons since ancient times. On the other hand, there is a wealth of knowledge in the medical books including medieval works of Middle Eastern polymaths such as Avicenna, “al-Rāzī,” and “Ṯābit ... -
Evaluating the accuracy of population-specific versus generic stature estimation regression equations in a South African sample
( Springer , 2024 , Article)Accurate estimates of stature play an important role in the personal identification of unknown decedents, however a drawback in the application of many stature estimation equations is the need for known sex and population, ... -
How global spine sagittal alignment and spinal degeneration affect locomotive syndrome risk in the elderly
( Springer , 2024 , Article)Background: The aim of this study was to delineate the features of the locomotive syndrome (LS) risk stage in the elderly population, encompassing global spine sagittal alignment, visible spinal degenerative changes on ... -
Cumulative Incidence of Venous Thromboembolic Events In-Hospital, and at 1, 3, 6, and 12 Months After Metabolic and Bariatric Surgery: Systematic Review of 87 Studies and Meta-analysis of 2,731,797 Patients
( Springer , 2024 , Article Review)Abstract: Systematic review/meta-analysis of cumulative incidences of venous thromboembolic events (VTE) after metabolic and bariatric surgery (MBS). Electronic databases were searched for original studies. Proportional ... -
Twelve-month prevalence, persistence, severity, and treatment of mood and anxiety disorders in Qatar's national mental health study
( John Wiley and Sons Ltd , 2024 , Article)Objectives To estimate 12-month prevalence, persistence, severity, and treatment of mental disorders and socio-demographic correlates in Qatar. Methods We conducted the first national population-based telephone survey ... -
Development of a 43 color panel for the characterization of conventional and unconventional T-cell subsets, B cells, NK cells, monocytes, dendritic cells, and innate lymphoid cells using spectral flow cytometry
( John Wiley and Sons Inc , 2024 , Article)Although many flow cytometers can analyze 30–50 parameters, it is still challenging to develop a 40+ color panel for the phenotyping of immune cells using fluorochrome conjugated antibodies due to limitations in the ... -
Recalcitrant pityriasis rubra pilaris in a Middle Eastern patient and arguments for early anti-IL-23 targeting
( John Wiley and Sons Inc , 2024 , Article)Pityriasis rubra pilaris (PRP) is a rare, chronic cutaneous inflammatory disorder of keratinization affecting adults, children and patients with HIV. The pathogenesis of PRP is not fully understood with clinical presentations, ... -
Impact of Previous Alopecia Areata Treatment on Efficacy Responses up to Week 48 Following Ritlecitinib Treatment: A Post Hoc Analysis
( Springer , 2024 , Article)Introduction Patients with alopecia areata (AA) may have received several therapies for management of AA during their lives. In the ALLEGRO phase 2b/3 (NCT03732807) study, the oral JAK3/TEC family kinase inhibitor ... -
Formulations and mechanisms of action of novel vaccine adjuvants
( Elsevier , 2024 , Book chapter)Vaccine adjuvants play a critical role in inducing optimal adaptive immune responses. Vaccine adjuvants can be lipids, metal-based, pathogen-based, and plant-based compounds. Few vaccine adjuvants are licensed for use in ... -
The dynamic role of immune checkpoint molecules in diagnosis, prognosis, and treatment of head and neck cancers
( Elsevier , 2024 , Article Review)Head and neck cancer (HNC) is the sixth most common cancer type, accounting for approximately 277,597 deaths worldwide. Recently, the Food and Drug Administration (FDA) has approved immune checkpoint blockade (ICB) agents ... -
Emerging Role of the IL-36/IL-36R Axis in Multiple Inflammatory Skin Diseases
( Elsevier , 2024 , Article Review)IL-36 is a most recent member of the IL-1 cytokine family, primarily expressed at barrier sites of the body such as the skin, lungs, and intestine. It plays a vital role in inflammation and is implicated in the development ... -
Chronic inflammation and cancer; the two sides of a coin
( Elsevier , 2024 , Article Review)The correlation between chronic inflammation and cancer was initially identified in the 19th century. Biomolecules like interleukins, chemokines, tumor necrosis factors, growth factors, and adhesion molecules, which regulate ... -
Urologist validation of an artificial intelligence-based tool for automated estimation of penile curvature
( Elsevier , 2024 , Article)Introduction Severity of penile curvature (PC) is commonly used to select the optimal surgical intervention for hypospadias, either alone or in conjunction with other phenotypic characteristics. Despite this, current ... -
Flushing New Light on Rosacea
( Elsevier , 2024 , Article)The study "Integrated omics reveal the molecular characterization and pathogenic mechanism of rosacea" (Zhang et al, 2023) presents the first multiomics integrative analysis comparing proteomic and transcriptomic signatures ... -
Reply to Letter to the Editor by Snodgrass et al. Re "Plate Objective Scoring Tool (POST) in distal hypospadias: Correlation with POST-repair complications
( Elsevier , 2024 , Article)Despite the popularity of TIP correction for distal hypospadias, certain publications have raised concerns about the accuracy of statements regarding its low complication rate [1]. Even skilled surgeons have observed a ...
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