Medicine Research: المرسلات الحديثة
السجلات المعروضة 101 -- 120 من 1509
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Hope on the Horizon: Promising Therapies for Steatotic Liver Disease
( The American Society for Pharmacology and Experimental Therapeutics , 2024 , Article Review)Steatotic liver disease (SLD) is a highly prevalent chronic liver disease with significant challenges for global health. The pathophysiology of SLD involves an interplay among genetic, endocrine, and metabolic factors. ... -
The Safety of Novel Therapies in Chronic Lymphocytic Leukemia in the Era of Intermittent Fasting: A Pharmacology-Based Review
( MDPI , 2024 , Article Review)Intermittent fasting (IF) has recently gained popularity due to its emerging benefits in reducing weight and improving metabolic health. Concurrently, novel agents (NAs) like venetoclax and Bruton tyrosine kinase inhibitors ... -
A malignant spiradenoma of the forehead: a case report and literature review
( Oxford University Press , 2024 , Article)Spiroadenomas, arising from sweat glands, are rare benign skin tumors primarily found as solitary nodules on the head, neck, and trunk. The malignant subtype, Spiradenocarcinoma (MSA), originating from benign spiradenomas, ... -
Brachydactyly type B: A rare case report and literature review
( Oxford University Press , 2024 , Article)Brachydactyly is a genetic condition leading to shortened or absent digits in hands or feet. It can occur independently or as part of syndromes. This case focuses on Brachydactyly type B, the rarest form. An 8-month-old ... -
Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight-loss interventions
( John Wiley and Sons Inc , 2024 , Article Review)Childhood obesity represents a significant public health concern, imposing a substantial burden on the healthcare system. Furthermore, weight-loss programs often exhibit reduced effectiveness in adults who have a history ... -
Comparing the metabolic signatures of obesity defined by waist circumference, waist-hip ratio, or BMI
( John Wiley and Sons Inc , 2024 , Article)Objective: Measuring obesity is crucial for assessing health risks and developing effective prevention and treatment strategies. The most common methods used to measure obesity include BMI, waist circumference, and waist-hip ... -
Short-term side effects of BNT162b2 vaccine in primary care settings in Qatar: a retrospective study
( Frontiers Media SA , 2024 , Article)Background: Despite the established effectiveness of the BNT162b2 Vaccine, the novel technology demands careful safety monitoring. While global studies have explored its safety, local data remains limited and exhibits some ... -
Out of the dark: the emerging roles of lncRNAs in pain
( Elsevier , 2024 , Article Review)The dark genome, the nonprotein-coding part of the genome, is replete with long noncoding RNAs (lncRNAs). These functionally versatile transcripts, with specific temporal and spatial expression patterns, are critical gene ... -
Report from the World Health Organization's immunization and vaccines-related implementation research advisory committee (IVIR-AC) meeting, virtual gathering, 26 February-1 March 2024
( Elsevier , 2024 , Conference Paper)The Immunization and Vaccine-related Implementation Research Advisory Committee (IVIR-AC) is the World Health Organization's key standing advisory body to conduct an independent review of research, particularly of transmission ... -
Corrigendum to "Report from the World Health Organization's immunization and vaccines-related implementation research advisory committee (IVIR-AC) meeting, virtual gathering, 26 February-1 March 2024" [Vaccine 42(15) (2024) 3379-3383, (S0264410X24004948), (10.1016/j.vaccine.2024.04.057)]
( Elsevier , 2024 , Article)The authors regret an incorrect affiliation (j) for co-author Dr. Kathy Leung, which should be corrected to School of Public Health, The University of Hong Kong, Hong Kong SAR, China. The authors would like to apologise ... -
Association between COVID-19 vaccination and stroke: a nationwide case-control study in Qatar
( Elsevier , 2024 , Article)Objective: This study investigated the association between Coronavirus Disease 2019 mRNA vaccination and stroke in Qatar. Methods: Between December 1, 2020, and April 11, 2023, a matched case-control study was conducted ... -
The effectiveness of the WHO school mental health package in promoting mental health literacy among secondary school teachers in Qatar: a randomized controlled trial
( BioMed Central Ltd , 2024 , Article)Teachers' mental health literacy (MHL) is fundamental for recognizing and assisting students with mental disorders. The aim of this study was to assess the effectiveness of the World Health Organization School Mental Health ... -
Kv7 Channel Activators Flupirtine and ML213 Alleviate Neuropathic Pain Behavior in the Streptozotocin Rat Model of Diabetic Neuropathy
( Dove Press Ltd , 2024 , Article)Background & Objective: Chronic peripheral neuropathic pain (PNP) is a debilitating condition that is associated with many types of injury/diseases, including diabetes mellitus. Patients with longstanding diabetes develop ... -
Adrenoceptor Desensitization: Current Understanding of Mechanisms
( The American Society for Pharmacology and Experimental Therapeutics , 2024 , Article Review)G-protein coupled receptors (GPCRs) transduce a wide range of extracellular signals. They are key players in the majority of biologic functions including vision, olfaction, chemotaxis, and immunity. However, as essential ... -
Tumor-type agnostic, targeted therapies make a new step forward: The first tumor-agnostic approval of a HER2-targeted therapy
( the Association of Basic Medical Sciences , 2024 , Article)Oncologic treatment has recently undergone substantial therapeutic paradigm shifts, from classical tumor-specific and biomarker-agnostic approaches to more molecular, biomarker-specific, and tumor-agnostic. Tumor-type ... -
Proteomic Analysis of Prehypertensive and Hypertensive Patients: Exploring the Role of the Actin Cytoskeleton
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Hypertension is a pervasive and widespread health condition that poses a significant risk factor for cardiovascular disease, which includes conditions such as heart attack, stroke, and heart failure. Despite its widespread ... -
Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health
( Springer , 2024 , Article Review)Obesity is a leading cause of morbidity and mortality globally. While the prevalence of obesity has been increasing, the incidence of its related complications including dyslipidemia and cardiovascular disease (CVD) has ... -
Impact of Obesity-Related Endoplasmic Reticulum Stress on Cancer and Associated Molecular Targets
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Obesity, characterized by excessive body fat, is closely linked to endoplasmic reticulum (ER) stress, leading to insulin resistance and type 2 diabetes. Inflammatory pathways like c-Jun N-terminal kinase (JNK) worsen insulin ... -
Association between Serum Vitamin D Status and Circadian Syndrome: A Cross-Sectional Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Background: Circadian Syndrome (CircS) encompasses cardiometabolic risk factors and comorbidities, indicating an elevated susceptibility to cardiovascular disease and type 2 diabetes. Methods: This cross-sectional study ... -
Metabolomics Profiling of Stages of Coronary Artery Disease Progression
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Coronary artery disease (CAD) and atherosclerosis pose significant global health challenges, with intricate molecular changes influencing disease progression. Hypercholesterolemia (HC), hypertension (HT), and diabetes are ...
