Medicine Research: المرسلات الحديثة
السجلات المعروضة 1341 -- 1360 من 1449
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Water-pipe smoking and serum testosterone levels in adult males in Qatar.
( European Publishing , 2019 , Article)Water-pipe (WP) smoking is the most common method of tobacco consumption in the Middle-East and is rapidly spreading on a global scale. Although, water-pipe smoking is linked to various diseases, such as emphysema and ... -
Novel therapeutic targets in salivary duct carcinoma uncovered by comprehensive molecular profiling.
( Wiley Open Access , 2019 , Article)Salivary duct carcinoma (SDC) is a rare, aggressive salivary gland malignancy, which often presents at an advanced stage. A proportion of SDC are characterized by HER2 amplification and/or overexpression of androgen receptor ... -
Molecular profiling reveals novel targetable biomarkers in neuroendocrine carcinoma of the uterine cervix
( Oxford University Press , 2019 , Conference Paper)Background Neuroendocrine carcinoma of the uterine cervix (NEC) is a rare cervical malignancy, accounting for 0.9% of all cervical carcinomas. Cervical NEC is a high-grade cancer with an aggressive clinical course and ... -
Mucocele of the appendix presenting as an exacerbated chronic tubo-ovarian abscess: A case report and comprehensive review of the literature.
( Lippincott, Williams & Wilkins , 2019 , Article)Appendiceal mucocele is a rare entity of mucinous cystic dilatation of the appendix. It has no typical clinical presentation and is considered a potentially premalignant condition. We present a case of accidental intraoperative ... -
Comprehensive analysis of cancers of unknown primary for the biomarkers of response to immune checkpoint blockade therapy
( Elsevier Ltd , 2018 , Article)Background: Cancer of unknown primary (CUP) accounts for approximately 3% of all malignancies. Avoiding immune destruction is a major cancer characteristic and therapies aimed at immune checkpoint blockade are in use for ... -
In Response: Heterogeneous and dynamic prevalence of asymptomatic influenza virus infections
( Centers for Disease Control and Prevention (CDC) , 2018 , Article)In Response: We thank Leung and Cowling (1) for taking time to comment on our article (2). One problem with the random effects model is the rapid decline in performance of the model as the heterogeneity within studies ... -
COL4A5 and LAMA5 variants co-inherited in familial hematuria: Digenic inheritance or genetic modifier effect?
( BioMed Central Ltd. , 2018 , Article)Background: About 40-50% of patients with familial microscopic hematuria (FMH) caused by thin basement membrane nephropathy (TBMN) inherit heterozygous mutations in collagen IV genes (COL4A3, COL4A4). On long follow-up, ... -
In vitro effects of hydrogen peroxide on rat uterine contraction before and during pregnancy
( Medicinska Naklada Zagreb , 2018 , Article)Aim To assess the in vitro effect of hydrogen peroxide (H 2 O 2 ) on uterine contractions in pregnant and non-pregnant rats. Methods The study was performed at the Department of Physiology, College of Medicine, King Saud ... -
In honour of Professor Leaf Huang, recipient of the Journal of Drug Targeting's life-time achievement award for 2018
( Taylor and Francis Ltd , 2018 , Article)[No abstract available] -
A History of Drug-Induced Torsades de Pointes Is Associated With T-wave Morphological Abnormalities
( Nature Publishing Group , 2018 , Article)The hypothesis of the study is that Torsades de pointes (TdP) history can be better identified using T-wave morphology compared to Fridericia-corrected QT interval (QTcF) at baseline. ECGs were recorded at baseline and ... -
Cytokine responses in campylobacteriosis: Linking pathogenesis to immunity
( Elsevier Ltd , 2018 , Article Review)Campylobacter jejuni is an important enteric pathogen that causes diarrheas of different degrees of severity and several extra-intestinal manifestations, including Guillain-Barre syndrome. The variability of disease outcomes ... -
A novel in ovo model to study cancer metastasis using chicken embryos and GFP expressing cancer cells.
( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2019 , Article)Cancer metastasis is the leading cause of cancer-related mortality worldwide. To date, several in vitro methodologies have been developed to understand the mechanisms of cancer metastasis and to screen various therapeutic ... -
Measurements of the talus in the assessment of population affinity
( Elsevier Ltd , 2018 , Article)© 2018 Elsevier B.V. As part of their routine work, forensic anthropologists are expected to report population affinity as part of the biological profile of an individual. The skull is the most widely used bone for the ... -
Dimensions around the nutrient foramina of the tibia and fibula in the estimation of sex
( Elsevier Ltd , 2018 , Article)© 2018 Elsevier B.V. Sex estimation from skeletal remains is one of the key components in establishing a biological profile and consequent identification of an individual in a forensic and medico-legal practice. The use ... -
Fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in castration-resistant prostate cancer cells: a potential therapeutic target
( Oxford University Press , 2019 , Article Review)In this short communication, a novel fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in prostate cancer is reviewed. In castration-resistant prostate cancer (CRPC) cells, the FABP5-related signal ... -
Detection of β-Arrestin-Mediated G Protein-Coupled Receptor Ubiquitination Using BRET.
( Humana Press, New York, NY , 2019 , Book chapter)Ubiquitination of G protein-coupled receptors (GPCRs) is an important dynamic posttranslational modification that has been linked to the intracellular trafficking of internalized GPCRs to lysosomes. Ubiquitination of GPCRs ... -
Molecular aspects of delta opioid receptors.
( Elsevier , 2019 , Article)The delta opioid receptor (DOP) belongs to the Class A, rhodopsin-like family of G protein-coupled receptors. Although this receptor has a high level of similarity with the other opioid receptors, it displays unique aspects ... -
Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.
( Springer Nature , 2019 , Article)Signaling diversity of G protein-coupled (GPCR) ligands provides novel opportunities to develop more effective, better-tolerated therapeutics. Taking advantage of these opportunities requires identifying which effectors ... -
Biomarkers of Targeted Therapy and Immuno-Oncology in Cancers Metastatic to the Breast.
( Lippincott, Williams & Wilkins , 2019 , Article)The breast is a rare site for metastases, and their molecular characteristics have not been studied yet. Intrinsic molecular genetics, cancer characteristics, and breast tissue immune responses in diverse metastases to the ... -
Changing Trends in the Referral and Timing of Treatment for Congenital Cryptorchidism: A Single-Center Experience from Bosnia and Herzegovina.
( Elsevier , 2019 , Article)Cryptorchidism is the most common male urogenital tract disorder identified at birth. Treatment delays of cryptorchidism may be associated with significant complications such as subfertility and testicular cancer. The ...