Medicine Research: المرسلات الحديثة
السجلات المعروضة 61 -- 80 من 1509
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Deciphering metabolomics and lipidomics landscape in zebrafish hypertrophic cardiomyopathy model
( Springer Nature , 2024 , Article)To elucidate the lipidomic and metabolomic alterations associated with hypertrophic cardiomyopathy (HCM) pathogenesis, we utilized cmybpc3-/- zebrafish model. Fatty acid profiling revealed variability of 10 fatty acids ... -
Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021
( Elsevier , 2024 , Article)BackgroundSmoking is the leading behavioural risk factor for mortality globally, accounting for more than 175 million deaths and nearly 4·30 billion years of life lost (YLLs) from 1990 to 2021. The pace of decline in smoking ... -
Erratum: Assessing the consistency of iPSC and animal models in cystic fibrosis modelling: A meta-analysis. (PLoS ONE (2022) 17:8 (e0272091) DOI: 10.1371/journal.pone.0272091)
( Public Library of Science , 2024 , Article)There are errors in the Funding section. The correct Funding statement is: The author acknowledges Qatar National Library for funding the publication of the article. -
Corrigendum to “P value–driven methods were underpowered to detect publication bias: analysis of Cochrane review meta-analyses”, Journal of Clinical Epidemiology, volume 118, (2020), 86-92.
( Elsevier , 2024 , Article)The authors regret Tinh Doan’s affiliation in the paper ‘‘Department of Statistics, Florida State University, Tallahassee, FL, USA’’ is incorrect. Tinh Doan’s correct affiliation is ‘‘ANU College of Health and Medicine, ... -
Defining the exit meta-Analysis
( Wolters Kluwer Health , 2024 , Article)Introduction: In recent decades, clinical research has seen significant advancements, both in the generation and synthesis of evidence through meta-Analyses. Despite these methodological advancements, there is a growing ... -
Sensitive objective markers for measuring aspirin responsiveness in pregnancy: An explorative scoping review
( Elsevier , 2024 , Article)BackgroundAspirin is frequently used in pregnancy to decrease the risk of developing pre-eclampsia. Studies have highlighted this potential benefit which in theory happens by inhibition of platelet function. However, ... -
Ischemic stroke as an initial presentation of neurosyphilis in a newly diagnosed HIV patient: A case report and literature review.
( Wiley , 2024 , Article)With syphilis resurgence, physicians should be more vigilant to infection-induced cerebral vasculitis in high-risk patients presenting with neurological symptoms. In this case, neurosyphilis should not be missed. Thorough ... -
Coexistence of brain capillary telangiectasia and venous angioma: A case report and literature review.
( Wiley , 2024 , Article)While Cerebral vascular malformations exhibit distinct clinical and radiographical features, rare instances of coexisting lesions occur. This case report sheds light on the rare coexistence of brain capillary telangiectasia ... -
Generation of human-induced pluripotent stem cells from a patient with homozygous I1234V mutation of cystic fibrosis.
( Hamad bin Khalifa University Press , 2024 , Article)Cystic fibrosis (CF) is an inherited autosomal recessive disorder. The most predominant mutation among Qatari patients with CF is the homozygous I1234V mutation, which is more prevalent in a Bedouin tribe.1 There are no ... -
Postoperative recovery after suspension suture placement at the site of esophagojejunal anastomosis after total gastrectomy: Comparison of two surgical techniques.
( IOS Press , 2024 , Article)Despite improvements, survival rates for gastric cancer remain low, even in developed countries, confirming the role of primary and secondary prevention. This study aims to demonstrate the role of additional suspension ... -
Impact of birth weight to placental weight ratio and other perinatal risk factors on left ventricular dimensions in newborns: A prospective cohort analysis
( Walter de Gruyter , 2024 , Article)Objectives: To investigate the association between birth weight to placental weight (BW/PW) ratio, and echocardiographic left ventricle (LV) morphology at birth, while accounting for other relevant perinatal factors. ... -
Impact of bariatric surgery on circulating irisin levels: a systematic review and meta‑analysis
( Springer Nature , 2024 , Article)This systematic review and meta-analysis evaluated changes in circulating irisin levels after bariatric surgery. A systematic search was performed across Embase, Scopus, PubMed, and Web of Science for this study. The ... -
The Impact of COVID-19 on the HIV Cascade of Care in Botswana – An Interrupted Time Series
( Springer Nature , 2024 , Article)Globally, Botswana has one of the highest burdens of HIV. This study estimated the impact of the COVID-19 pandemic on the HIV cascade of care in Sub-Saharan Africa. We conducted an interrupted time series analysis on ... -
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
( John Wiley & Sons , 2024 , Article)Calmodulin (CaM) is a ubiquitous, small cytosolic calcium (Ca2+)-binding sensor that plays a vital role in many cellular processes by binding and regulating the activity of over 300 protein targets. In cardiac muscle, CaM ... -
The Plasma Glucose Threshold Values Associated with Adverse Pregnancy Outcomes Among Asian Indian Pregnant Women: MAASTHI Birth Cohort Analysis.
( Dove Press Ltd , 2024 , Article)To assess the association of adverse pregnancy and infant outcomes with different cut-off levels of glucose intolerance during pregnancy in the MAASTHI cohort. Pregnant women (n = 1470) underwent Oral glucose tolerance ... -
The mammalian sperm factor phospholipase C zeta is critical for early embryo division and pregnancy in humans and mice
( Oxford University Press , 2024 , Article)STUDY QUESTION Are sperm phospholipase C zeta (PLCζ) profiles linked to the quality of embryogenesis and pregnancy? SUMMARY ANSWER Sperm PLCζ levels in both mouse and humans correlate with measures of ideal embryogenesis ... -
No Remdesivir Resistance Observed in the Phase 3 Severe and Moderate COVID-19 SIMPLE Trials
( MDPI , 2024 , Article)Remdesivir (RDV) is a broad-spectrum nucleotide analog prodrug approved for the treatment of COVID-19 in hospitalized and non-hospitalized patients with clinical benefit demonstrated in multiple Phase 3 trials. Here we ... -
Perceptions and Experiences of Pursuing Research Among Medical Students in Problem-Based Learning Curriculum: A Cross-Sectional Study from Qatar
( SAGE Publications , 2024 , Article)OBJECTIVES Early introduction to research prepares medical students for the practice of evidence-based medicine. Few studies have examined the experiences of research among medical students in the Arab region. This study ... -
Comprehensive genomic profiling of pediatric peritoneal mesothelioma: case report with a literature review
( Oxford University Press , 2024 , Article)Malignant peritoneal mesothelioma is an extremely rare and poorly recognized neoplasm in children. A 5-year-old boy presented with a 1-year history of progressive painless abdominal distension. A CT revealed a 19 x 19 x ... -
Phytochemical-mediated modulation of autophagy and endoplasmic reticulum stress as a cancer therapeutic approach
( John Wiley and Sons Ltd , 2024 , Article Review)Autophagy and endoplasmic reticulum (ER) stress are conserved processes that generally promote survival, but can induce cell death when physiological thresholds are crossed. The pro-survival aspects of these processes are ...
