Medicine Research: Recent submissions
Now showing items 1021-1040 of 1448
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The prevalence of HEV among non-A-C hepatitis in Qatar and efciency of serological markers for the diagnosis of hepatitis E
( BMC , 2021 , Article)Background: The rapid growth of Qatar in the last two decades has attracted a large influx of immigrant workers who mostly come from HEV-hyperendemic countries. Thus, we aim to investigate the prevalence of HEV among acute ... -
Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress
( Elsevier , 2021 , Article)Endoplasmic reticulum (ER) stress is an inflammatory response that contributes to endothelial dysfunction, a hallmark of cardiovascular diseases, in close interplay with oxidative stress. Recently, Sestrin2 (SESN2) emerged ... -
Advances in Diagnostic and Molecular Pathology
( NLM (Medline) , 2021 , Other)No abstract available -
The Role of Pathology in the Era of Personalized (Precision) Medicine: A Brief Review.
( NLM (Medline) , 2021 , Article)This review provides a brief overview of the state-of-the-art molecular pathology approaches emphasizing the increasingly important pathology role in clinical precision cancer medicine. Recent advances in molecular biology ... -
Serum 25-Hydroxyvitamin D Is Inversely Associated with Monocyte Percentage to HDL Cholesterol Ratio among Young Healthy Adults in Qatar
( MDPI , 2021 , Article)Low serum 25-hydroxyvitamin D [25(OH)D] is linked to an altered lipid profile. Monocytes play an important role in inflammation and lipid metabolism. Recently, monocyte percentage to HDL-cholesterol ratio (MHR) has emerged ... -
High-risk human papillomaviruses and Epstein-Barr virus in breast cancer in Lebanese women and their association with tumor grade: a molecular and tissue microarray study.
( BMC , 2021 , Article)High-risk human papillomaviruses (HPVs) are present and can cooperate with Epstein-Barr virus (EBV) to initiate and/or enhance the progression of several types of human carcinomas including cervical as well as head and ... -
Bias Assessment in Outcomes Research: The Role of Relative Versus Absolute Approaches
(2021 , Article)ObjectivesBias assessment tools vary in content and detail, and the method used for assessment may produce different assessment results in a study if not carefully considered. Therefore, taking an approach to the assessment ... -
Gravitational Influence on Human Living Systems and the Evolution of Species on Earth
( MDPI , 2021 , Article Review)Gravity constituted the only constant environmental parameter, during the evolutionary period of living matter on Earth. However, whether gravity has affected the evolution of species, and its impact is still ongoing. The ... -
A Rare Sequela of Constriction Band Syndrome: Case Report.
( Lippincott, Williams & Wilkins , 2021 , Report)The patient in this case report is a 19-year-old man who presented with left foot cauliflower lesion. He complained of an inability to wear proper shoes, in addition to an unpleasant appearance of his foot. The lesion was ... -
Intestinal obstruction caused by a clamped persistent omphalomesenteric duct in congenital hernia into the umbilical cord.
( Wiley , 2021 , Article)A congenital hernia into the umbilical cord (CHUM) is often misinterpreted as a mild form of omphalocele. Herniated content in CHUM can be either the solitary intestinal loop or persistent omphalomesenteric duct (POMD) ... -
Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
( Elsevier , 2021 , Article)HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. It is characterized by aggressive behavior and treatment resistance. On the other hand, poly (amidoamine) (PAMAM) ... -
Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment.
( Springer , 2021 , Article)Metabolic dysregulation in the hypoxic tumor microenvironment (TME) is considered as a hallmark of solid tumors, leading to changes in biosynthetic pathways favoring onset, survival and proliferation of malignant cells. ... -
An Early Warning Tool for Predicting Mortality Risk of COVID-19 Patients Using Machine Learning
( Springer , 2021 , Article)COVID-19 pandemic has created an extreme pressure on the global healthcare services. Fast, reliable, and early clinical assessment of the severity of the disease can help in allocating and prioritizing resources to reduce ... -
Microneedles: A new generation vaccine delivery system
( MDPI , 2021 , Article Review)Transdermal vaccination route using biodegradable microneedles is a rapidly progressing field of research and applications. The fear of painful needles is one of the primary reasons most people avoid getting vaccinated. ... -
Exploring the effect of image enhancement techniques on COVID-19 detection using chest X-ray images
( Elsevier , 2021 , Article)Computer-aided diagnosis for the reliable and fast detection of coronavirus disease (COVID-19) has become a necessity to prevent the spread of the virus during the pandemic to ease the burden on the healthcare system. Chest ... -
Oncoproteins of High-Risk HPV and EBV Cooperate to Enhance Cell Motility and Invasion of Human Breast Cancer Cells Erk1/Erk2 and β-Catenin Signaling Pathways.
( Frontiers Media , 2021 , Article)Breast cancer is a leading cause of death in women around the world. Most breast cancer-related deaths are a result of complications from the metastatic spread. Several recent studies reported that high-risk human ... -
Regulation of NKG2D by RKIP: Implications on NK-mediated cytotoxicity and cytokine production
( Elsevier , 2021 , Book chapter)RKIP (Raf kinase inhibitory protein) is a metastatic suppressor and a chemo-immuno-sensitizer. The deficiency or loss of RKIP has been linked with different cancer types, resulting in the activation of the MAPK pathway, ... -
Information, Thermodynamics and Life: A Narrative Review
( MDPI , 2021 , Article Review)Information is probably one of the most difficult physical quantities to comprehend. This applies not only to the very definition of information, but also to the physical entity of information, meaning how can it be ... -
Personalized telehealth in the future: A global research agenda
( JMIR Publications Inc. , 2016 , Article Review)As telehealth plays an even greater role in global health care delivery, it will be increasingly important to develop a strong evidence base of successful, innovative telehealth solutions that can lead to scalable and ...