Medicine Research: Recent submissions
Now showing items 1141-1160 of 1449
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Circulating miRNAs in HER2-Positive and Triple Negative Breast Cancers: Potential Biomarkers and Therapeutic Targets.
( MDPI , 2020 , Article)Breast cancer is one of the most prevalent diseases among women worldwide and is highly associated with cancer-related mortality. Of the four major molecular subtypes, HER2-positive and triple-negative breast cancer (TNBC) ... -
Decreased number of acute appendicitis cases in pediatric population during the COVID-19 pandemic: Any link?
( Elsevier , 2020 , Article)The reasons behind the decrease in AA frequency during the COVID-19 pandemic remain unclear. Some authors have proposed that milder forms can be treated conservatively at home [15] or using antibiotics. Snapiri et al. also ... -
Thujone inhibits the function of 7-nicotinic acetylcholine receptors and impairs nicotine-induced memory enhancement in one-trial passive avoidance paradigm
( Elsevier Ireland Ltd , 2017 , Article)Effects of thujone, a major ingredient of absinthe, wormwood oil and some herbal medicines, were tested on the function of 7 subunit of the human nicotinic acetylcholine (7 nACh) receptor expressed in Xenopus oocytes using ... -
In honour of Professor Ruth Duncan, recipient of the Journal of Drug Targeting's Lifetime Achievement Award for 2017
( Taylor and Francis Ltd , 2017 , Other)[No abstract available] -
Colonial management of death
( SAGE Publications , 2020 , Article)During the late 1960s, Israel had a policy of withholding Palestinian corpses in secret cemeteries, in which each corpse was designated by a number, called the ‘secret cemeteries of numbers’. During the last Palestinian ... -
Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats
( Elsevier B.V. , 2017 , Article)The critical role of α1-glycine receptor (α1-GLYRs) in pathological conditions such as epilepsy is well known. In the present study, structure-activity relations for a series of phenylalanine derivatives carrying selected ... -
This House believes that considering the continuous quarantine and precautionary measures should be of a priority over lifting the restrictions to avoid the negative economic and social consequences
( College of Medicine - Qatar University , 2020 , Video)NA -
Covid-19: Challenges & Perspectives
( College of Medicine - Qatar University , 2020 , Conference Program)A Virtual Conference to shed light on the QU's prominent trends and research efforts addressing Corona virus. -
What is open-access publishing and what it means for the forensic enterprise
( Elsevier B.V. , 2019 , Article)Science is a public endeavor the results of which are intended to be shared with other scientists, professionals, and the public [1]. This is viewed as a worldwide right: Article 27 of the United Nations Declaration of ... -
First sliding Amyand hernia harbouring appendicular schistosomiasis: Case report
( Elsevier Ltd , 2019 , Article)Introduction: Amyand's hernia (AH) is rare, schistosomiasis of the appendix is very uncommon, and both conditions coexisting together is an extremely rare event. Pre-operative diagnosis of each of the two conditions is ... -
Improved liquid phase separation processes for generating biodegradable microspheres loaded with high concentrations of drugs for tumor embolization
( Taylor and Francis Inc. , 2019 , Article)Drug-eluting microspheres are the most commonly used particulate embolic agents for transarterial chemoembolization of liver tumors. However, drug loading of degradable embolic particles is often insufficient. In the current ... -
Novel biomarkers for potential risk stratification of drug induced liver injury (DILI): A narrative perspective on current trends
( Lippincott Williams and Wilkins , 2019 , Article)Background:Drug induced liver injury (DILI) is an increasing cause of acute liver injury especially with increasing need for pharmacotherapy of widening comorbidities amongst our ever-aging population. Uncertainty however ... -
Primary vs Revisional Gastric Bypass for Weight Loss and Improvements in Comorbidities: Comparisons at Mid-term Follow-up
( Springer , 2019 , Article)Background: Revisional gastric bypass (R-RYGB) surgery is utilized for the management of inadequate weight loss or weight regain observed after some cases of bariatric surgeries. Data on the mid-term effectiveness of primary ... -
Proteomics of transforming growth factor ?1 (TGF ?1) signaling in 184A1 human breast epithelial cells suggests the involvement of casein kinase 2? in TGF ?1-dependent p53 phosphorylation at Ser392
( Morion LLC , 2019 , Article)Aim: Transforming growth factor ?1 (TGF ?1) is a potent regulator of breast tumorigenesis. It inhibits proliferation of carcinoma cells, but the strength of its inhibitory action varies for cells from benigh, non-metastatic ... -
Glycosylation is a novel TGF?1-independent post-translational modification of Smad2
( Elsevier B.V. , 2019 , Article)Smad2 is a crucial component of intracellular signaling by transforming growth factor-? (TGF?). Here we describe that Smad2 is glycosylated, which is a novel for Smad2 post-translational modification. We showed that the ... -
Prenatal alcohol exposure is associated with early motor, but not language development in a South African cohort
( Cambridge University Press , 2019 , Article)Objective:To investigate the association of prenatal alcohol exposure (PAE) and early neurodevelopment in the first 2 years of life, adjusting for maternal sociodemographic and psychosocial factors, in the Drakenstein Child ... -
It is all about patients' stories: Case-based learning in residents' education
( Hamad Medical Corporation , 2019 , Article)Background: Problem-based learning (PBL) is an inquiry-based learning strategy which is learner centered and facilitates group discussion and critical thinking. Case-based learning (CBL), which is a more guided approach ... -
Acquisition of invasiveness by breast adenocarcinoma cells engages established hallmarks and novel regulatory mechanisms
( International Institute of Anticancer Research , 2019 , Article)Background/Aim: Proteomics of invasiveness opens a window on the complexity of the metastasis-engaged mechanisms. The extend and types of this complexity require elucidation. Materials and Methods: Proteomics, immuno ... -
Co-presence of human papillomaviruses and Epstein-Barr virus is linked with advanced tumor stage: a tissue microarray study in head and neck cancer patients.
( BMC , 2020 , Article)Human papillomaviruses (HPVs) and Epstein-Barr virus (EBV), known oncoviruses, can be co-present and cooperate in the initiation and/or progression of human carcinomas, including head and neck. Based on this fact, we ... -
SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities.
( MDPI , 2020 , Article Review)Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to ...