Medicine Research: Recent submissions
Now showing items 961-980 of 1448
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Adrenal abscess in a preterm neonate with sepsis
( Elsevier , 2021 , Article)The adrenal abscess is a rare complication of adrenal hemorrhage in the neonatal period. Due to its rare occurrence and non-specific signs, diagnosing and treating an adrenal abscess in the neonatal period might be ... -
Characterising Alzheimer's disease through integrative NMR- and LC-MS-based metabolomics
( Elsevier , 2021 , Article)BackgroundAlzheimer's Disease (AD) is a complex and multifactorial disease and novel approaches are needed to illuminate the underlying pathology. Metabolites comprise the end-product of genes, transcripts, and protein ... -
Shotgun-based proteomics of extracellular vesicles in Alzheimer’s disease reveals biomarkers involved in immunological and coagulation pathways
( Nature Research , 2021 , Article)Alzheimer’s disease (AD) is the most common form of dementia and without readily available clinical biomarkers. Blood-derived proteins are routinely used for diagnostics; however, comprehensive plasma profiling is challenging ... -
Identifying metabolic alterations in newly diagnosed small cell lung cancer patients
( Elsevier , 2021 , Article)BackgroundSmall cell lung cancer (SCLC) is a malignant disease with poor prognosis. At the time of diagnosis most patients are already in a metastatic stage. Current diagnosis is based on imaging, histopathology, and ... -
Association between pre-existing conditions and hospitalization, intensive care services and mortality from COVID-19 - a cross sectional analysis of an international global health data repository
( Qatar University Press , 2021 , Poster)Objective: To investigate the association between pre-existing conditions and hospitalization, need for intensive care services (ICU) and mortality due to COVID-19. Methods: We used data on all cases recorded in the Global ... -
Proteomic profile in congenital microcephaly
( Qatar University Press , 2021 , Poster)Autosomal recessive primary microcephaly (MCPH) consists of a group of disorders characterized by microcephaly and intellectual disability. This study is essential to complement previous findings of MCPH as it helps clarify ... -
The prevalence of adaptive immunity to COVID-19 and reinfection after recovery - a comprehensive systematic review and meta-analysis of 12 011 447 individuals
( Qatar University Press , 2021 , Poster)Research purpose: The research aims to estimate the prevalence of detectable SARS-CoV-2 antibodies, T and B memory cells after recovery, to determine the prevalence of SARS-CoV-2 reinfection, and to investigate the protective ... -
The risk of severe COVID-19 and mortality from COVID-19 in people living with HIV compared to individuals without HIV - a systematic review and meta-analysis of 1 268 676 individuals.
( Qatar University Press , 2021 , Poster)Research Purpose: Findings from existing studies have shown conflicting evidence concerning the risk of severe COVID-19 and death from COVID-19 in people living with HIV (PLHIV) compared to people without HIV. The aim of ... -
Pyocyanin pigment from Pseudomonas aeruginosa modulates innate immune defenses in macrophages
( Qatar University Press , 2021 , Poster)Background: Pseudomonas aeruginosa is a well-known opportunistic pathogen. The gram-negative bacillus, commonly associated with hospital-acquired infections, utilizes the host's impaired immune responses to establish ... -
Prevalence of Asymptomatic Hyperuricemia and its Association with Prediabetes, Dyslipidemia and Subclinical Inflammation Markers among Young Healthy Adults in Qatar
( Qatar University Press , 2021 , Poster)Aim: To investigate the prevalence of asymptomatic hyperuricemia in Qatar and to examine its association with changes in markers of dyslipidemia, prediabetes and subclinical inflammation. Methods: A cross-sectional study ... -
Exploring QU Health Students' Experiences of Burnout, Anxiety, and Empathy during the COVID-19 Pandemic: A Mixed Method Study
( Qatar University Press , 2021 , Poster)Background Students' mental health is a growing concern. COVID-19 pandemic resulted in academic and non-academic challenges which caused students' burnout, anxiety, and reduced empathy. Objectives The study objectives were ... -
Comparison of Available Methods for Investigating The in vitro Activity of Colistin Against Different Gram-Negative Bacilli
( Qatar University Press , 2021 , Poster)Background: The surge in the prevalence of multidrug-resistant (MDR) Gram-negative bacterial infections with limited treatment options and the decrease in the development of new antibiotics are challenges that lead to the ... -
Barriers and Facilitators to Mental Health Help-seeking among Older Adults: A Systematic Review
( Qatar University Press , 2021 , Poster)Background: Older adults are very unlikely to seek mental health help. There are multiple factors that contribute to a person's final decision to seek formal help. The aim of this study is to systematically review and ... -
Development of Novel Chalcone Analogs as Potential Multi-Targeted Therapies for Castration-Resistant Prostate Cancer
( Qatar University Press , 2021 , Poster)Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of ... -
Evaluation of antiviral activity of Manuka honey against SARS-CoV-2.
( Qatar University Press , 2021 , Poster)Background and aims: In 2020 a global pandemic was declared caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2). The pandemic is still ongoing and continues to cause considerable mortality and morbidity ... -
The Combination of Dasatinib and PD L1 inhibitor prevents the progression of epithelial mesenchymal transition and dramatically blocks cell invasion of HER2 positive breast cancer cells
( Qatar University Press , 2021 , Poster)Introduction: Both Dasatinib (DA), a tyrosine kinase inhibitor that is used for targeted cancer therapy, and programmed death-ligand 1 (PD-1/PD-L1) inhibitor that is an immune checkpoint therapy, play a vital role in the ... -
Elaeagnus Angustifolia extract inhabits cell invasion of human colorectal cancer cells and increases the survival rate of the Drosophila colon cancer model
( Qatar University Press , 2021 , Poster)Colorectal cancer (CRC), the third most common type of cancer in the world, is an aggressive type of cancer with high tendency to metastasize and invade to other tissues and distant organs. Traditional CRC treatment regimen ... -
Risk prediction of early decline in renal function in diabetic kidney disease with algorithm including fractional excretion of glycated amino acids
( Qatar University Press , 2021 , Poster)Background and aims: Diabetic kidney disease occurs in ca. 40% patients with diabetes. Approximately 1 in 5 patients with type 1 diabetes mellitus (T1DM) and 1 in 3 patients with type 2 diabetes mellitus (T2DM) develop ... -
Pilot Evaluation of the “Practice Educators’ Academy” Preceptor Development Program for Continuing Health Professional Education Programs in Qatar
( Qatar University Press , 2021 , Poster)"The Practice Educators' Academy Program" is an innovative educational intervention developed following a preceptor-focused needs assessment. This study evaluated the program's effect on self-efficacy and knowledge amongst ... -
Contribution of Glycosaminoglycan binding in CCL21-mediated Migration of Breast Cancer cells
( Qatar University Press , 2021 , Poster)Lymph node metastasis constitutes a key event in Breast Cancer progression and it is a process at least partially mediated by the chemokine CCR7. Chemokine function is dependent upon their binding to both cell-surface ...