Faculty Contributions: Recent submissions
Now showing items 401-420 of 19920
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Impact of Previous Alopecia Areata Treatment on Efficacy Responses up to Week 48 Following Ritlecitinib Treatment: A Post Hoc Analysis
( Springer , 2024 , Article)Introduction Patients with alopecia areata (AA) may have received several therapies for management of AA during their lives. In the ALLEGRO phase 2b/3 (NCT03732807) study, the oral JAK3/TEC family kinase inhibitor ... -
Formulations and mechanisms of action of novel vaccine adjuvants
( Elsevier , 2024 , Book chapter)Vaccine adjuvants play a critical role in inducing optimal adaptive immune responses. Vaccine adjuvants can be lipids, metal-based, pathogen-based, and plant-based compounds. Few vaccine adjuvants are licensed for use in ... -
Anti-Neuralgic Medications
( wiley , 2024 , Book chapter)This chapter discusses the common types of oral medications used in the management of neuralgic pain with a focus on trigeminal neuralgia. The general principles of management of orofacial pain are outlined followed by a ... -
Management of Medical Emergencies
( wiley , 2024 , Book chapter)This chapter discusses the recognition and management of common medical emergencies which may be encountered in dental practice. General guidelines on prevention and management of medical emergencies are considered along ... -
The dynamic role of immune checkpoint molecules in diagnosis, prognosis, and treatment of head and neck cancers
( Elsevier , 2024 , Article Review)Head and neck cancer (HNC) is the sixth most common cancer type, accounting for approximately 277,597 deaths worldwide. Recently, the Food and Drug Administration (FDA) has approved immune checkpoint blockade (ICB) agents ... -
Emerging Role of the IL-36/IL-36R Axis in Multiple Inflammatory Skin Diseases
( Elsevier , 2024 , Article Review)IL-36 is a most recent member of the IL-1 cytokine family, primarily expressed at barrier sites of the body such as the skin, lungs, and intestine. It plays a vital role in inflammation and is implicated in the development ... -
Chronic inflammation and cancer; the two sides of a coin
( Elsevier , 2024 , Article Review)The correlation between chronic inflammation and cancer was initially identified in the 19th century. Biomolecules like interleukins, chemokines, tumor necrosis factors, growth factors, and adhesion molecules, which regulate ... -
Urologist validation of an artificial intelligence-based tool for automated estimation of penile curvature
( Elsevier , 2024 , Article)Introduction Severity of penile curvature (PC) is commonly used to select the optimal surgical intervention for hypospadias, either alone or in conjunction with other phenotypic characteristics. Despite this, current ... -
Flushing New Light on Rosacea
( Elsevier , 2024 , Article)The study "Integrated omics reveal the molecular characterization and pathogenic mechanism of rosacea" (Zhang et al, 2023) presents the first multiomics integrative analysis comparing proteomic and transcriptomic signatures ... -
Reply to Letter to the Editor by Snodgrass et al. Re "Plate Objective Scoring Tool (POST) in distal hypospadias: Correlation with POST-repair complications
( Elsevier , 2024 , Article)Despite the popularity of TIP correction for distal hypospadias, certain publications have raised concerns about the accuracy of statements regarding its low complication rate [1]. Even skilled surgeons have observed a ... -
The role of preoperative transfusion in sickle cell disease, a systematic review and meta-analysis
( Elsevier , 2024 , Article Review)This systematic review and meta-analysis aimed to provide guidance on preoperative blood transfusion strategies for patients with sickle cell disease (SCD). We included all randomized controlled and observational studies ... -
Plate Objective Scoring Tool (POST) in distal hypospadias: Correlation with post-repair complications
( Elsevier , 2024 , Article)Objectives The Plate Objective Scoring Tool (POST) accurately reflects configuration of the urethral plate in distal hypospadias. Here we assessed whether POST score also correlates with patient risk of complications after ... -
Determinants and prediction of hypertension among Chinese middle-aged and elderly adults with diabetes: A machine learning approach
( Elsevier , 2024 , Article)Objective: Multimorbidity, particularly diabetes combined with hypertension (DCH), is a significant public health concern. Currently, there is a gap in research utilizing machine learning (ML) algorithms to predict ... -
A multi-objective planning and scheduling model for elective and emergency cases in the operating room under uncertainty
( Elsevier , 2024 , Article)Hospitals are paramount hubs for delivering healthcare services, with their Operating Rooms (ORs) as a pivotal and financially substantial component. Efficient surgery ward planning is crucial in healthcare institutions, ... -
Hypospadias-associated penile curvature assessment and management: A global survey of current practice
( Elsevier , 2024 , Article)Introduction: Our goal was to assess how surgical management of hypospadias-associated penile curvature (HAPC) varies across continents, focusing on factors that influence assessment and decision-making. Methods: Members ... -
The effect of colchicine on myocardial infarction: An updated systematic review and meta-analysis of randomized controlled trials
( Elsevier , 2025 , Article)INTRODUCTION: Myocardial infarction (MI) is associated with a significant post-event inflammatory response which further contributes to post-MI prognosis. Colchicine, an anti-inflammatory agent, exhibits potential benefits ... -
Efficacy and safety of norepinephrine versus phenylephrine for post-spinal hypotension in preeclamptic patients: A systematic review and meta-analysis
( Elsevier , 2024 , Article Review)Objective: We conducted a systematic review and meta-analysis to evaluate the fetomaternal outcomes after the administration of norepinephrine or phenylephrine for the treatment of post spinal hypotension in preeclamptic ... -
Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour
( Elsevier , 2024 , Article)Early implant failure and bone resorption may occur in load-bearing conditions as a result of stress shielding brought on by a mismatch in the bone-Ti-implant modulus. A review with a novel multidisciplinary perspective ... -
Pathogenic mechanisms, diagnostic, and therapeutic potential of microvesicles in diabetes and its complications
( Elsevier , 2024 , Article Review)Extracellular vesicles (EVs), particularly microvesicles (MVs), have gained significant attention for their role as mediators of intercellular communication in both physiological and pathological contexts, including diabetes ... -
Flavonoids, gut microbiota and cardiovascular disease: Dynamics and interplay
( Elsevier , 2024 , Article Review)Cardiovascular disease (CVD) remains the leading cause of global morbidity and mortality. Extensive efforts have been invested to explicate mechanisms implicated in the onset and progression of CVD. Besides the usual ...
