Faculty Contributions: Recent submissions
Now showing items 421-440 of 19948
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Universal Genetic Testing for Newly Diagnosed Invasive Breast Cancer
( American Medical Association , 2024 , Article)IMPORTANCE Between 5% and 10% of breast cancer cases are associated with an inherited germline pathogenic or likely pathogenic variant (GPV) in a breast cancer susceptibility gene (BCSG), which could alter local and systemic ... -
In vivo assessment of the nephrotoxic effects of the synthetic cannabinoid AB-FUBINACA
( Springer , 2024 , Article)Background: The widespread misuse of synthetic cannabinoids (SCs) has led to a notable increase in reported adverse effects, raising significant health concerns. SCs use has been particularly associated with acute kidney ... -
The Hall technique: knowledge, practice, and concerns of dentists in primary care settings in the State of Qatar-a questionnaire-based survey
( Springer , 2024 , Article)Purpose: To assess the knowledge, practice, and concerns about the Hall Technique among pediatric dentists (PDs) and general dental practitioners (GDPs) working in primary care settings in the State of Qatar. Methods: A ... -
Development of a 43 color panel for the characterization of conventional and unconventional T-cell subsets, B cells, NK cells, monocytes, dendritic cells, and innate lymphoid cells using spectral flow cytometry
( John Wiley and Sons Inc , 2024 , Article)Although many flow cytometers can analyze 30–50 parameters, it is still challenging to develop a 40+ color panel for the phenotyping of immune cells using fluorochrome conjugated antibodies due to limitations in the ... -
Recalcitrant pityriasis rubra pilaris in a Middle Eastern patient and arguments for early anti-IL-23 targeting
( John Wiley and Sons Inc , 2024 , Article)Pityriasis rubra pilaris (PRP) is a rare, chronic cutaneous inflammatory disorder of keratinization affecting adults, children and patients with HIV. The pathogenesis of PRP is not fully understood with clinical presentations, ... -
Ferulic acid: extraction, estimation, bioactivity and applications for human health and food
( John Wiley and Sons Ltd , 2024 , Article Review)Ferulic acid ((E)-3-(4-hydroxy-3-methoxy-phenyl) prop-2-enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of ... -
Medication-Related Osteonecrosis of Jaws
( wiley , 2024 , Book chapter)This chapter discusses the common types of medications associated with medication-related osteonecrosis of jaw (MRONJ) including bisphosphates, monoclonal antibodies and anti-angiogenic agents. Risk assessment of patients, ... -
Local Anaesthetics
( wiley , 2024 , Book chapter)This chapter discusses the common types of injectable and topical local anaesthetics used for pain control in clinical dentistry. The classification, mechanism of action, constituents, contraindications, side effects, ... -
Impact of Previous Alopecia Areata Treatment on Efficacy Responses up to Week 48 Following Ritlecitinib Treatment: A Post Hoc Analysis
( Springer , 2024 , Article)Introduction Patients with alopecia areata (AA) may have received several therapies for management of AA during their lives. In the ALLEGRO phase 2b/3 (NCT03732807) study, the oral JAK3/TEC family kinase inhibitor ... -
Formulations and mechanisms of action of novel vaccine adjuvants
( Elsevier , 2024 , Book chapter)Vaccine adjuvants play a critical role in inducing optimal adaptive immune responses. Vaccine adjuvants can be lipids, metal-based, pathogen-based, and plant-based compounds. Few vaccine adjuvants are licensed for use in ... -
Anti-Neuralgic Medications
( wiley , 2024 , Book chapter)This chapter discusses the common types of oral medications used in the management of neuralgic pain with a focus on trigeminal neuralgia. The general principles of management of orofacial pain are outlined followed by a ... -
Management of Medical Emergencies
( wiley , 2024 , Book chapter)This chapter discusses the recognition and management of common medical emergencies which may be encountered in dental practice. General guidelines on prevention and management of medical emergencies are considered along ... -
The dynamic role of immune checkpoint molecules in diagnosis, prognosis, and treatment of head and neck cancers
( Elsevier , 2024 , Article Review)Head and neck cancer (HNC) is the sixth most common cancer type, accounting for approximately 277,597 deaths worldwide. Recently, the Food and Drug Administration (FDA) has approved immune checkpoint blockade (ICB) agents ... -
Emerging Role of the IL-36/IL-36R Axis in Multiple Inflammatory Skin Diseases
( Elsevier , 2024 , Article Review)IL-36 is a most recent member of the IL-1 cytokine family, primarily expressed at barrier sites of the body such as the skin, lungs, and intestine. It plays a vital role in inflammation and is implicated in the development ... -
Chronic inflammation and cancer; the two sides of a coin
( Elsevier , 2024 , Article Review)The correlation between chronic inflammation and cancer was initially identified in the 19th century. Biomolecules like interleukins, chemokines, tumor necrosis factors, growth factors, and adhesion molecules, which regulate ... -
Urologist validation of an artificial intelligence-based tool for automated estimation of penile curvature
( Elsevier , 2024 , Article)Introduction Severity of penile curvature (PC) is commonly used to select the optimal surgical intervention for hypospadias, either alone or in conjunction with other phenotypic characteristics. Despite this, current ... -
Flushing New Light on Rosacea
( Elsevier , 2024 , Article)The study "Integrated omics reveal the molecular characterization and pathogenic mechanism of rosacea" (Zhang et al, 2023) presents the first multiomics integrative analysis comparing proteomic and transcriptomic signatures ... -
Reply to Letter to the Editor by Snodgrass et al. Re "Plate Objective Scoring Tool (POST) in distal hypospadias: Correlation with POST-repair complications
( Elsevier , 2024 , Article)Despite the popularity of TIP correction for distal hypospadias, certain publications have raised concerns about the accuracy of statements regarding its low complication rate [1]. Even skilled surgeons have observed a ... -
The role of preoperative transfusion in sickle cell disease, a systematic review and meta-analysis
( Elsevier , 2024 , Article Review)This systematic review and meta-analysis aimed to provide guidance on preoperative blood transfusion strategies for patients with sickle cell disease (SCD). We included all randomized controlled and observational studies ... -
Plate Objective Scoring Tool (POST) in distal hypospadias: Correlation with post-repair complications
( Elsevier , 2024 , Article)Objectives The Plate Objective Scoring Tool (POST) accurately reflects configuration of the urethral plate in distal hypospadias. Here we assessed whether POST score also correlates with patient risk of complications after ...
