Browsing Pharmacy Research by Publisher "American Chemical Society (ACS)"

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6-Formylindolo(3,2-b)carbazole Dampens Inflammation and Reduces Endotoxin-Induced Kidney Injury via Nrf2 Activation

Dhulkifle, Hevna; Sayed, Tahseen S.; Abunada, Hanan H.; Abulola, Sara M.; Alhoshani, Ali; Korashy, Hesham M.; Maayah, Zaid H.... more authors ... less authors ( American Chemical Society (ACS) , 2023 , Article)
Patients with sepsis are at a high risk of morbidity and mortality due to multiple organ injuries caused by pathological inflammation. Although sepsis is accompanied by multiple organ injuries, acute renal injury is a ...
Apabetalone (RVX-208): A Potential Epigenetic Therapy for the Treatment of Cardiovascular, Renal, Neurological, Viral, and Cancer Disorders

Dhulkifle, Hevna; Diab, Mohammad Issam; Algonaiah, Majed; Korashy, Hesham M.; Maayah, Zaid H. ( American Chemical Society (ACS) , 2024 , Article)
Bromodomain and extra-terminal domain proteins (BET proteins) are epigenetic reader proteins that have been implicated in regulating gene expression through binding to chromatin and interaction with transcription factors. ...