Pharmacy Research: المرسلات الحديثة
السجلات المعروضة 421 -- 440 من 1370
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Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation
( Elsevier , 2020 , Article)AimThe aim of this study was to improve the therapeutic index of chemotherapeutic drugs on glioblastoma cells through an improved co-drug delivery system. Materials and methodsMethotrexate (MTX) and paclitaxel (PTX) were ... -
Letter to the Editor Response
( Elsevier , 2020 , Article)To the Editor We thank Dr. Luis Rafael Moscote-Salazar and Dr. Amit Agrawal for their interest in our recently published article in the Journal.1 The authors do not raise any concerns about the scientific facts and the ... -
Regulation of Autophagy via Carbohydrate and Lipid Metabolism in Cancer
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Metabolic changes are an important component of tumor cell progression. Tumor cells adapt to environmental stresses via changes to carbohydrate and lipid metabolism. Autophagy, a physiological process in mammalian cells ... -
Applications of polydopaminic nanomaterials in mucosal drug delivery
( Elsevier , 2023 , Article Review)Polydopamine (PDA) is a biopolymer with unique physicochemical properties, including free-radical scavenging, high photothermal conversion efficiency, biocompatibility, biodegradability, excellent fluorescent and theranostic ... -
Following drug degradation and consequent taste deterioration of an oral reconstituted paediatric suspension during dosing interval via electronic tongue
( Elsevier , 2022 , Article)BackgroundThe taste of oral liquid dosage forms is a crucial factor that impacts pediatric patient compliance. Taste of suspensions can be typically evaluated by human volunteers. Recently, the electronic tongue (ET) has ... -
Phenethyisoquinoline alkaloids from the leaves of Androcymbium palaestinum
( Elsevier , 2020 , Article)Thirteen compounds were isolated from the methanolic extract of the leaves of Androcymbium palaestinum Baker (Colchicaceae). Of these, three were new, two were new natural products, and eight were known. The new isolated ... -
Analysis of fatalities involving amphetamine in Jazan, Saudi Arabia
( Elsevier , 2021 , Article)Amphetamine use is associated with high tendence of homicidal or suicidal deaths and fatalities making amphetamine a persistent area of concern. This study analyzed fatalities associated with amphetamine use in Jazan city, ... -
Knowledge, attitude, and readiness towards disaster management: A nationwide survey among healthcare practitioners in United Arab Emirates
( Public Library of Science , 2023 , Article)Health professionals are expected to be knowledgeable on disaster medicine and prepared to deal with medicine disasters. This study aimed to assess the level of knowledge, attitude, and readiness to practice disaster ... -
Recent developments on (−)-colchicine derivatives: Synthesis and structure-activity relationship
( Elsevier , 2020 , Article Review)(−)-Colchicine, an anti-microtubulin polymerization agent, is a valuable medication and the drug of choice for gout, Behçet’s disease and familial Mediterranean fever. It has a narrow therapeutic index due to its high ... -
Perceptions and expectations of health professionals regarding hospital pharmacy services and the roles of hospital pharmacists: A qualitative systematic review and meta-synthesis
( Elsevier , 2023 , Article)BackgroundPharmacists have become increasingly integrated within the interprofessional hospital team as their scope of practice expanded in recent decades. However, limited research has explored how the roles of hospital ... -
Materiovigilance in Perspective: Understanding Its Concept and Practice in the Global Healthcare System
( Springer , 2023 , Article)Materiovigilance (Mv) has the same purpose and approach in ensuring patient safety as pharmacovigilance but deals with medical devices associated with adverse events (MDAEs) and their monitoring. Mv has been instrumental ... -
Minimizing prescribing errors: A phenomenological exploration of the views and experiences of independent prescribing pharmacists
( Wiley-Blackwell , 2023 , Article)Aims: This study aims to explore the views and experiences of independent prescribing (IP) pharmacists regarding prescribing errors and strategies to mitigate errors in practice. Methods: One-to-one online semi-structured ... -
Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B
( Elsevier , 2020 , Article)Previous studies have established the role of Na+/H+ exchanger isoform-1 (NHE1) and cathepsin B (Cat B) in the development of cardiomyocyte hypertrophy (CH). Both NHE1 and Cat B are activated under acidic conditions ... -
Suicide literacy mediates the path from religiosity to suicide stigma among Muslim community adults: Cross-sectional data from four Arab countries.
( SAGE , 2023 , Article)The majority of research attention has been devoted to the link between religiosity and suicide risk, and a considerable amount of studies has been carried out on how stigma impacts individuals with mental health problems ... -
Antimicrobial stewardship programme implementation in the UAE: perspectives of key stakeholders using Consolidated Framework for Implementation Research
( Elsevier , 2023 , Article)BackgroundMany studies report antimicrobial stewardship programme (ASP) implementation, but these are limited by a lack of theoretical underpinning. This may lead to missing key factors that are likely to influence the ... -
A Qualitative Exploration of Health Profession Students’ Experiences of Resilience and Burnout Using the Coping Reservoir Model during the COVID-19 Pandemic
( Taylor & Francis , 2023 , Article)Phenomenon: The Coping Reservoir Model is a useful theoretical and analytical framework through which to examine student resilience and burnout. This model conceptualizes wellbeing as a reservoir which is filled or drained ... -
Pharmacist-driven antimicrobial stewardship interventions in patients with COVID-19: a scoping review
( Springer Nature , 2023 , Article)Background: Coronavirus Disease 2019 (COVID-19) is a highly infectious disease that can be treated with antivirals in addition to other antimicrobials in cases of secondary or concomitant infections. This creates potential ... -
Antibiotic Use Among Hospitalized Patients in Africa: A Systematic Review of Point Prevalence Studies
( Springer Nature , 2023 , Article)Background: There is paucity of data describing the rate and quality indices of antibiotics used among hospitalized patients at continental level in Africa. This systematic review evaluated the pooled prevalence, indications, ... -
Regulation of Autophagy via Carbohydrate and Lipid Metabolism in Cancer
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Metabolic changes are an important component of tumor cell progression. Tumor cells adapt to environmental stresses via changes to carbohydrate and lipid metabolism. Autophagy, a physiological process in mammalian cells ... -
Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues
( MDPI , 2022 , Article Review)Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at the single-cell level and possess an unprecedented potential for exploring signatures involved in tumor development and progression. ...
