Pharmacy Research: Recent submissions
Now showing items 521-540 of 1233
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A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country
( Springer Science and Business Media Deutschland GmbH , 2022 , Article)Background: Sodium glucose co-transporter 2 inhibitors (SGLT2is) are a novel class of oral antidiabetic drugs. To date, there are no pharmacoepidemiologic studies investigating the pattern of use of SGLT2is compared to ... -
Adding colchicine to tocilizumab in hospitalized patients with severe COVID-19 pneumonia: An open-label randomized controlled trial
( Lippincott Williams and Wilkins , 2022 , Article)Introduction: Colchicine acts upstream in the cytokines cascade by inhibiting the nod-like receptor protein 3 (NLRP3) inflammasome while interleukin 6 (IL-6) receptor antagonists, such as tocilizumab, block the end result ... -
An HIV-STI risk reduction program among undergraduate students at a northern Nigerian university: A randomized controlled field trial
(2012 , Article)Aim This study aims to evaluate the effectiveness of a peer-led human immunodeficiency virus-sexually transmitted infections (HIV-STI) intervention program based on the Information-Motivation-Behavioral Skills model among ... -
Attitudes and beliefs regarding the use of herbs and supplementary medications with COVID-19: A systematic review
( Elsevier , 2022 , Article)Background and aimThere is growing interest in using herbs and supplementary medications to treat and/or prevent COVID-19, evidenced by multiple reports exploring their effectiveness and safety. From a health psychology ... -
From an Apple to a Pear: Moving Fat around for Reversing Insulin Resistance.
( MDPI , 2022 , Article Review)Type 2 diabetes (T2D) is a chronic condition where the body is resistant to insulin, leading to an elevated blood glucose state. Obesity is a main factor leading to T2D. Many clinical studies, however, have described a ... -
Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells
( Taylor and Francis Group , 2021 , Article)Forkhead box M1 (FoxM1) is a transcription factor that plays an important role in the etiology of many cancers, however, its role has not been elucidated in B-precursor acute lymphoblastic leukemia (B-pre-ALL). In the ... -
Learning needs assessments in continuing professional development: A scoping review
( Taylor and Francis Group , 2022 , Article)Background: A rigorous learning needs assessment (LNA) is a crucial initial step in the Continuing Professional Development (CPD) process. This scoping review aimed to collate, summarize, and categorize the reported LNA ... -
Characteristics of drug-related problems and pharmacist’s interventions in hospitalized patients in Thailand: a prospective observational study
( Nature Portfolio , 2022 , Article)Drug-related problems (DRPs) are a major health concern. A better understanding of the characteristics of DRPs throughout the hospital stay may help to tailor pharmaceutical care services (PCS). This study aims to describe ... -
Amniotic stem cells as a source of regenerative medicine to treat female infertility
( Springer , 2022 , Article Review)Impaired reproductive health is a worldwide problem that affects the psychological well-being of a society. Despite the technological developments to treat infertility, the global infertility rate is increasing significantly. ... -
In Vitro and In Vivo Validation of GATA-3 Suppression for Induction of Adipogenesis and Improving Insulin Sensitivity
( MDPI , 2022 , Article)Impaired adipogenesis is associated with the development of insulin resistance and an increased risk of type 2 diabetes (T2D). GATA Binding Protein 3 (GATA3) is implicated in impaired adipogenesis and the onset of insulin ... -
Comparing the Metabolic Profiles Associated with Fitness Status between Insulin-Sensitive and Insulin-Resistant Non-Obese Individuals
( MDPI , 2022 , Article)(1) Background: Young non-obese insulin-resistant (IR) individuals could be at risk of developing metabolic diseases including type 2 diabetes mellitus. The protective effect of physical activity in this apparently healthy ... -
Molecular Modeling Guided Drug Designing for the Therapeutic Treatment of Rheumatoid Arthritis
( Hindawi , 2022 , Article)Rheumatoid arthritis (RA) is a systemic inflammatory disorder that can cause destructive joint disease, significant disability, and increased mortality. RA is the most frequent of all chronic inflammatory joint diseases, ... -
Formation of biocompatible MgO/cellulose grafted hydrogel for efficient bactericidal and controlled release of doxorubicin
( Elsevier B.V. , 2022 , Article)In this study, MgO-doped CNC-g-PAA hydrogel was synthesized by grafting poly (acrylic acid) (PAA) onto cellulose nanocrystals (CNC) and then doped Magnesium oxide (MgO) using pH 7.0 and 12.0 to obtain an efficient nanocomposite ... -
Antihypertensive potential of Brassica rapa leaves: An in vitro and in silico approach
( Frontiers Media , 2022 , Article)Aim: Plants contain many essential constituents and their optimization can result in the discovery of new medicines. One such plant is Brassica rapa that is commonly used as a vegetable to fulfill daily food requirements ... -
Effect of different antidiabetic medications on atherosclerotic cardiovascular disease (ASCVD) risk score among patients with type-2 diabetes mellitus: A multicenter noninterventional observational study
( PLOS , 2022 , Article)Objective The aim of this study was to compare the clinical outcomes associated with different combinations of oral diabetic drugs among patients with type 2 diabetes mellitus. Method A prospective multicenter longitudinal, ... -
Patient satisfaction with inpatient pharmacy services at tertiary care setting—a meta-analysis of recent literature
( Oxford University Press , 2022 , Article)Objectives This study aimed to determine patient satisfaction with the following pharmacist-led services for inpatients in tertiary care hospitals. Methods Studies were identified from different databases from 2012 ... -
Evaluation of self-reported knowledge and understanding towards a blended research course among pharmacy students: Objective Search Literature Evaluation (OSLE) method validation
( International Pharmaceutical Federation (FIP) , 2022 , Article)Background: The objective of the study was to evaluate the impact of classroom versus online Modular object-oriented dynamic learning environment (MOODLE)-based teaching on objective search literature evaluation (OSLE) ... -
Choice of Antimicrobials in Surgical Prophylaxis - Overuse and Surgical Site Infection Outcomes from a Tertiary-Level Care Hospital
( Frontiers Media , 2022 , Article)Background: This study was aimed to describe the choice of Surgical Antimicrobial Prophylaxis at a tertiary-level care hospital in United Arab Emirates. It also associated the choice between two leading antimicrobials for ... -
A Meta-Analysis on Clinical Outcomes of Ceftolozane versus Piperacillin in Combination with Tazobactam in Patients with Complicated Urinary Tract Infections
( Hindawi , 2022 , Article Review)Objective. To evaluate efficacy and adverse events of ceftolozane/tazobactam in complicated UTI including acute pyelonephritis. Method. Databases that include PubMed, Embase, Scopus, and TRIP were searched. All randomized ... -
Effects of polyphenol-rich traditional herbal teas on obesity and oxidative stress in rats fed a high-fat–sugar diet
( John Wiley & Sons, Ltd. , 2022 , Article)Hibiscus rosa-sinensis and Zingiber officinalis teas are traditionally used for the therapies of various diseases, including obesity. The present research work was planned to appraise the potential of polyphenol-rich ...