Pharmacy Research: Recent submissions
Now showing items 61-80 of 1315
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Cost-effectiveness of l-glutamine versus crizanlizumab for adults with sickle cell disease: model focused on reducing pain episode costs from Qatar's healthcare perspective
( SAGE Publications Ltd , 2024 , Article)Objectives: Treatment options for preventing vaso-occlusive crises among sickle cell disease patients are on the rise, especially if hydroxyurea treatment has failed. This economic analysis is conducted to assess the ... -
Unlocking the Therapeutic Potential of BCL-2 Associated Protein Family: Exploring BCL-2 Inhibitors in Cancer Therapy
( Korean Society of Applied Pharmacology , 2024 , Article Review)Apoptosis, programmed cell death pathway, is a vital physiological mechanism that ensures cellular homeostasis and overall cellular well-being. In the context of cancer, where evasion of apoptosis is a hallmark, the ... -
Short-term side effects of BNT162b2 vaccine in primary care settings in Qatar: a retrospective study
( Frontiers Media SA , 2024 , Article)Background: Despite the established effectiveness of the BNT162b2 Vaccine, the novel technology demands careful safety monitoring. While global studies have explored its safety, local data remains limited and exhibits some ... -
Influence of automated indexing in Medical Subject Headings (MeSH) selection for pharmacy practice journals
( Elsevier , 2024 , Article)Background: The Medical Subject Headings (MeSH) thesaurus is the controlled vocabulary used to index articles in MEDLINE. MeSH were mainly manually selected until June 2022 when an automated algorithm, the Medical Text ... -
A Cross-Sectional Study of Vaccination-Related Education in Pharmacy Programs in the Middle East
( Elsevier , 2024 , Article)Objective: Pharmacists play pivotal roles in improving vaccination rates. However, absence of vaccination-related undergraduate education impedes their ability for these roles. The study aims were to scope vaccination-related ... -
Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
( Elsevier , 2024 , Report)BackgroundMicroRNAs (miRNAs) participate in diverse cellular changes following acute ischemic stroke (AIS). Circulating miRNAs, stabilized and delivered to target cells via extracellular vesicles (EVs), are potential ... -
Structural proteomics guided annotation of vaccine targets and designing of multi-epitopes vaccine to instigate adaptive immune response against Francisella tularensis
( Elsevier , 2024 , Article)Francisella tularensis can cause severe disease in humans via the respiratory or cutaneous routes and a case fatality ratio of up to 10 % is reported due to lack of proper antibiotic treatment, while F. novicida causes ... -
In silico design of multi-epitope vaccines against the hantaviruses by integrated structural vaccinology and molecular modeling approaches
( Public Library of Science , 2024 , Article)Hantaviruses are single-stranded RNA viruses belonging to the family Bunyaviridae that causes hantavirus cardiopulmonary syndrome (HCPS) and hemorrhagic fever with renal syndrome (HFRS) worldwide. Currently, there is no ... -
Integrated structural proteomics and machine learning-guided mapping of a highly protective precision vaccine against mycoplasma pulmonis
( Elsevier , 2024 , Article)Mycoplasma pulmonis (M. pulmonis) is an emerging respiratory infection commonly linked to prostate cancer, and it is classified under the group of mycoplasmas. Improved management of mycoplasma infections is essential due ... -
Kv7 Channel Activators Flupirtine and ML213 Alleviate Neuropathic Pain Behavior in the Streptozotocin Rat Model of Diabetic Neuropathy
( Dove Press Ltd , 2024 , Article)Background & Objective: Chronic peripheral neuropathic pain (PNP) is a debilitating condition that is associated with many types of injury/diseases, including diabetes mellitus. Patients with longstanding diabetes develop ... -
Inhibition of cytochrome P450 epoxygenase promotes endothelium-to-mesenchymal transition and exacerbates doxorubicin-induced cardiovascular toxicity
( Springer Nature , 2024 , Article)Background: Doxorubicin (DOX) is a potent chemotherapy widely used in treating various neoplastic diseases. However, the clinical use of DOX is limited due to its potential toxic effect on the cardiovascular system. Thus, ... -
Imatinib‑ and ponatinib‑mediated cardiotoxicity in zebrafish embryos and H9c2 cardiomyoblasts
( Spandidos Publications , 2024 , Article)Tyrosine kinase inhibitors (TKIs) offer targeted therapy for cancers but can cause severe cardiotoxicities. Determining their dose‑dependent impact on cardiac function is required to optimize therapy and minimize adverse ... -
The evolving role of pharmacists in depression care: a scoping review
( Springer Science and Business Media Deutschland GmbH , 2024 , Article Review)Background: Worldwide, depression is known to contribute significantly to the global burden of disease. Considering pharmacists are among the most approachable healthcare providers, they are well-placed to assist people ... -
Coronavirus Disease 2019 Knowledge, Its Vaccine Uptake Intentions, and the Influence of Personality Traits among Undergraduate Pharmacy Students in a University Setting: Findings and Implications
( Wolters Kluwer Medknow Publications , 2024 , Article)Context: Coronavirus disease 2019 (COVID-19) is the greatest global health catastrophe of the century, with its vaccine hesitancy compounding the woes. Relevant stakeholders, including pharmacy students (whose education ... -
A scoping review of the questionnaires used for the assessment of the perception of undergraduate students of the learning environment in healthcare professions education programs
( Springer Science and Business Media B.V. , 2024 , Article Review)The learning environment (LE) includes social interactions, organizational culture, structures, and physical and virtual spaces that influence the learning experiences of students. Despite numerous studies exploring the ... -
Exploring the perceptions of faculty members about research courses in undergraduate pharmacy curriculum: A qualitative study
( Public Library of Science , 2024 , Article)Introduction and objective The commitment of pharmacy graduates to patient care and research is crucial to advancing pharmaceutical science and practice. Consequently, the value of involving undergraduate pharmacy students ... -
Potential Anti-Tumorigenic Properties of Diverse Medicinal Plants against the Majority of Common Types of Cancer
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Globally, cancer is one of the primary causes of both morbidity and mortality. To prevent cancer from getting worse, more targeted and efficient treatment plans must be developed immediately. Recent research has demonstrated ... -
QPGx-CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies
( John Wiley and Sons Inc , 2024 , Article Review)Pharmacogenetic (PGx)-informed medication prescription is a cutting-edge genomic application in contemporary medicine, offering the potential to overcome the conventional "trial-and-error" approach in drug prescription. ... -
Impact of COVID-19 on antimicrobial stewardship program: Study protocol
( Elsevier , 2024 , Article)The coronavirus disease (COVID-19) pandemic affects the healthcare system worldwide and challenges many governments and institutions. Antimicrobial stewardship program advocating the wise use of antimicrobial agents. Its ... -
Patients' knowledge, attitude, and practices toward unused medications in Qatar: A cross-sectional survey
( Elsevier , 2024 , Article)Background: Global evidence has linked unused medications and their inappropriate disposal to adverse health, economic, environmental, and ethical impacts. However, such evidence is scarce in Qatar. This study explored ...
