Browsing Mechanical & Industrial Engineering by Author "Kobeissy F."
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Culture of PC12 neuronal cells in GelMA hydrogel for brain tissue engineering
Al Rifai, N.; Hasan, Anwarul; Kobeissy, F.; Gazalah, H.; Charara, J. ( Institute of Electrical and Electronics Engineers Inc. , 2015 , Conference Paper)Restoration of brain functions following trauma or degenerative neural diseases is considered among the greatest challenges in neurology due to the fact that the central nervous system (CNS) does not regenerate on its own. ... -
Hydrogels for Advanced Stem Cell Therapies: A Biomimetic Materials Approach for Enhancing Natural Tissue Function
Farhat W.; Hasan A.; Lucia L.; Becquart F.; Ayoub A.; Kobeissy F.... more authors ... less authors ( Institute of Electrical and Electronics Engineers , 2018 , Article)Stem-cell-based therapy is a promising approach for the treatment of a myriad of diseases and injuries. However, the low rate of cell survival and the uncontrolled differentiation of the injected stem cells currently remain ... -
Modulation of proteomic and inflammatory signals by Bradykinin in podocytes
Saoud R.; Jaffa M.A.; Habib A.; Zhao J.; Al Hariri M.; Zhu R.; Hasan, Anwarul; Ziyadeh F.N.; Kobeissy F.; Mechref Y.; Jaffa A.A.... more authors ... less authors ( Elsevier B.V. , 2020 , Article)Podocyte damage is one of the hallmarks of diabetic nephropathy leading to proteinuria and kidney damage. The underlying mechanisms of podocyte injury are not well defined. Bradykinin (BK) was shown to contribute to diabetic ... -
Vascular cells proteome associated with bradykinin and leptin inflammation and oxidative stress signals
Hariri M.A.; Jaffa M.A.; Saoud R.; Zhao J.; Zhu R.; Jaffa A.A.; El-Achkar G.A.; Moussa M.; Kobeissy F.; Hassan A.; Ziyadeh F.N.; Mechref Y.; Jaffa A.A.... more authors ... less authors ( MDPI , 2020 , Article)Among the primary contributors to cardiovascular diseases are inflammation and oxidative imbalance within the vessel walls as well as the fibrosis of rat aortic smooth muscle cell (RASMC). Bradykinin (BK) and leptin are ...