Browsing Mechanical & Industrial Engineering by Author "Mraiche, Fatima"
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Cisplatin encapsulated nanoparticles from polymer blends for anti-cancer drug delivery
Joshy, K.S.; Augustine, Robin; Hasan, Anwarul; Ali Zahid, Alap; Alex, Susan M.; Dalvi, Yogesh B.; Mraiche, Fatima; Thomas, Sabu; Kalarikkal, Nandakumar; Chi, Hong... more authors ... less authors ( Royal Society of Chemistry , 2022 , Article)Developing novel nanocarriers for anticancer drug delivery has become a ‘promising niche’. The toxicity of the carrier and its efficacy in treatment modalities have become cardinal points as they can impede the progress ... -
Crosstalk between Sodium–Glucose Cotransporter Inhibitors and Sodium–Hydrogen Exchanger 1 and 3 in Cardiometabolic Diseases
Al-Shamasi, Al-Anood; Elkaffash, Rozina; Mohamed, Meram; Rayan, Menatallah; Al-Khater, Dhabya; Gadeau, Alain-Pierre; Ahmed, Rashid; Hasan, Anwarul; Eldassouki, Hussein; Yalcin, Huseyin Cagatay; Abdul-Ghani, Muhammad; Mraiche, Fatima... more authors ... less authors ( MDPI , 2021 , Article)Abnormality in glucose homeostasis due to hyperglycemia or insulin resistance is the hallmark of type 2 diabetes mellitus (T2DM). These metabolic abnormalities in T2DM lead to cellular dysfunction and the development of ... -
Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression
Abdulrahman, Nabeel; Ibrahim, Meram; Joseph, Jensa Mariam; Elkoubatry, Hanan Mahmoud; Al-Shamasi, Al Anood; Rayan, Menatallah; Gadeau, Alain Pierre; Ahmed, Rashid; Eldassouki, Hussein; Hasan, Anwarul; Mraiche, Fatima... more authors ... less authors ( Springer , 2022 , Article)Diabetes mellitus (DM)-induced cardiac morbidities have been the leading cause of death among diabetic patients. Recently, sodium-glucose cotransporter-2 (SGLT-2) inhibitors including empagliflozin (EMPA), which have been ... -
Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues
Ahmed, Rashid; Zaman, Tariq; Chowdhury, Farhan; Mraiche, Fatima; Tariq, Muhammad; Ahmad, Irfan S.; Hasan, Anwarul... more authors ... less authors ( MDPI , 2022 , Article Review)Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at the single-cell level and possess an unprecedented potential for exploring signatures involved in tumor development and progression. ...