Mechanical & Industrial Engineering: Recent submissions
Now showing items 741-760 of 1396
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3D printed nanocomposites for tailored cardiovascular tissue constructs: A minireview
( Elsevier B.V. , 2021 , Article)Cardiovascular diseases (CVD) with escalating death rates pose one of the greatest threats to global health and well-being. Thus, developing effective interventions to combat CVD are of critical importance. 3D printing ... -
Exploring the interaction of quercetin-3-O-sophoroside with SARS-CoV-2 main proteins by theoretical studies: A probable prelude to control some variants of coronavirus including Delta
( Elsevier B.V. , 2021 , Article)The aim of this study was to investigate the mechanism of interaction between quercetin-3-O-sophoroside and different SARS-CoV-2?s proteins which can bring some useful details about the control of different variants of ... -
An engineered microfluidic blood-brain barrier model to evaluate the anti-metastatic activity of β-boswellic acid
( John Wiley and Sons Inc , 2021 , Article)Background The development of anti-cancer drugs with the ability to inhibit brain metastasis through the blood-brain barrier (BBB) is substantially limited due to the lack of reliable in vitro models. Main Methods In ... -
Increased complications of COVID-19 in people with cardiovascular disease: Role of the renin-angiotensin-aldosterone system (RAAS) dysregulation
( Elsevier Ireland Ltd , 2022 , Article)The rapid spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID?19), has had a dramatic negative impact on public health and economies worldwide. Recent studies ... -
Investigating the Properties of Electrodeposited of Ni-P-ZrC Nanocomposite Coatings
( American Chemical Society , 2021 , Article)Superior corrosion resistance along with higher mechanical performance is becoming a primary requirement to decrease operational costs in the industries. Nickel-based phosphorus coatings have been reported to show better ... -
Spatial mapping of cancer tissues by OMICS technologies
( Elsevier B.V. , 2022 , Article)Spatial mapping of heterogeneity in gene expression in cancer tissues can improve our understanding of cancers and help in the rapid detection of cancers with high accuracy and reliability. Significant advancements have ... -
Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
( Elsevier B.V. , 2021 , Article)Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance. An N141I missense ... -
Sulfated alginate/polycaprolactone double-emulsion nanoparticles for enhanced delivery of heparin-binding growth factors in wound healing applications
( Elsevier B.V. , 2021 , Article)Diabetic foot ulcers (DFUs) that are not effectively treated could lead to partial or complete lower limb amputations. The lack of connective tissue growth factor (CTGF) and insulin-like growth factor (IGF-I) in DFUs results ... -
Enzyme?polymeric/inorganic metal oxide/hybrid nanoparticle bio-conjugates in the development of therapeutic and biosensing platforms
( Elsevier B.V. , 2021 , Article)Background: Because enzymes can control several metabolic pathways and regulate the production of free radicals, their simultaneous use with nanoplatforms showing protective and combinational properties is of great interest ... -
Diagnostic and drug release systems based on microneedle arrays in breast cancer therapy
( Elsevier B.V. , 2021 , Article)Microneedle arrays have recently received much attention as cancer detection and treatment platforms, because invasive injections and detection of the biopsy are not needed, and drug metabolism by the liver, as well as ... -
Enhancement of mechanical and corrosion resistance properties of electrodeposited NiP-TiC composite coatings
( Nature Research , 2021 , Article)In the present study, the effect of concentration of titanium carbide (TiC) particles on the structural, mechanical, and electrochemical properties of Ni–P composite coatings was investigated. Various amounts of TiC particles ... -
p53 signaling in cancer progression and therapy
( BioMed Central Ltd , 2021 , Article)The p53 protein is a transcription factor known as the "guardian of the genome" because of its critical function in preserving genomic integrity. The TP53 gene is mutated in approximately half of all human malignancies, ... -
The therapeutic effects of tumor treating fields on cancer and noncancerous cells
( Elsevier B.V. , 2021 , Article)Tumor treating fields (TTFields) are among clinically active anticancer modalities that utilize low?intensity, intermediate frequency (IF), and alternating electric fields (AEFs) to selectively disrupt mitosis in cancerous ... -
Exome sequencing of glioblastoma-derived cancer stem cells reveals rare clinically relevant frameshift deletion in MLLT1 gene
( BioMed Central Ltd , 2022 , Article)Background: Glioblastoma multiforme (GBM) is a heterogeneous CNS neoplasm which causes significant morbidity and mortality. One reason for the poor prognostic outcome of GBM is attributed to the presence of cancer stem ... -
Design of Titanium Alloy Femoral Stem Cellular Structure for Stress Shielding and Stem Stability: Computational Analysis
( MDPI , 2022 , Article)The main objective of this study is to design titanium alloy femoral stems with cubic porous structures that will be able to reduce stress shielding and promote stem stability. These porous structure designs were introduced ... -
Using Conditional Generative Adversarial Networks in Computational Mechanics -- Code
(2022 , Dataset)We use cGANs to solve computational mechanics. We model a structure using FEA and generate simulations results (deflection and stress). We then transform the FEA results into images where the colour channels correspond to ... -
Deep Learning for Reliable Classification of COVID-19, MERS, and SARS from Chest X-ray Images
( Springer , 2022 , Article)Novel coronavirus disease (COVID-19) is an extremely contagious and quickly spreading coronavirus infestation. Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), which outbreak in 2002 ... -
One-Dimensional Convolutional Neural Networks for Real-Time Damage Detection of Rotating Machinery
( Springer , 2022 , Conference Paper)This paper presents a novel real-time rotating machinery damage monitoring system. The system detects, quantifies, and localizes damage in ball bearings in a fast and accurate way using one-dimensional convolutional neural ... -
A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
( Elsevier B.V. , 2022 , Article)Cuttings removal out of the wellbore represents a real barrier for successful drilling operations. The performance of hole cleaning is determined by several factors. The current article provides a theoretical study of the ... -
Influence of fuel ratio on the performance of combustion synthesized bifunctional cobalt oxide catalysts for fuel cell application
( Elsevier Ltd , 2019 , Article)Solution combustion synthesis was used to prepare cobalt oxide nanoparticles at different fuel ratio (φ = 0.5, 1, and 1.75). The synthesized particles were characterized using XRD, SEM, TEM, FTIR and XPS to study the ...
