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25-Hydroxyvitamin D serum levels inversely correlate to disease severity and serum C-reactive protein levels in patients with hidradenitis suppurativa
(
Wiley
, 2021 , Other)
Vitamin D exerts functions in skin physiology by modulating keratinocyte proliferation and different immunoregulatory processes.1 In several dermatoses, vitamin D correlates to disease severity and is significantly lower ...
Proteomic study identifies glycolytic and inflammation pathways involved in recurrent otitis media
(
MDPI
, 2020 , Article)
Recurrent acute otitis media (RAOM) in children is clinically defined as the occurrence of at least three episodes of acute otitis media over a course of 6 months. A further common pathological condition of interest in the ...
Evaluation of residual infectivity after SARS-CoV-2 aerosol transmission in a controlled laboratory setting
(
MDPI
, 2021 , Article)
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is mainly transmitted through respiratory droplets, aerosols, or direct contact with fomites from an infected subject. It has been reported that SARS-CoV-2 ...
Molecular detection of SARS-CoV-2 from indoor air samples in environmental monitoring needs adequate temporal coverage and infectivity assessment
(
Elsevier
, 2021 , Article)
The relevance of airborne exposure to SARS-CoV-2 in indoor environments is a matter of research and debate, with special importance for healthcare low-risk settings. Experimental approaches to the bioaerosol sampling are ...
Multiomics integration in skin diseases with alterations in notch signaling pathway: PlatOMICs phase 1 deployment
(
MDPI
, 2021 , Article Review)
The high volume of information produced in the age of omics was and still is an important step to understanding several pathological processes, providing the enlightenment of complex molecular networks and the identification ...
CIITA gene polymorphism (rs3087456) in systemic lupus erythematosus and rheumatoid arthritis: A population-based cohort study
(
Wiley
, 2021 , Other)
Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are influenced by genetic variants in immune system HLA genes. The Class II Major Histocompatibility Complex Transactivator (CIITA) is an important co-activator ...
In silico analysis of molecular interactions between HIV-1 glycoprotein gp120 and TNF receptors
(
Elsevier
, 2021 , Article)
Proinflammatory microenvironmental is crucial for the Human Immunodeficiency Virus Type 1 (HIV-1) pathogenesis. The viral glycoprotein 120 (gp120) must interact with the CD4+ T cell chemokine receptor (CCR5) and a co-receptor ...
Blue photobiomodulation LED therapy impacts SARS-CoV-2 by limiting its replication in Vero cells
(
Wiley
, 2021 , Other)
The study of any intervention able to counteract SARS-CoV-2 pandemic is considerably envisaged. It was previously shown, in in vitro models of infections, that the LED blue light is able to decrease the viral load of HSV-1 ...
Lipid transfer proteins (Ltps)- structure, diversity and roles beyond antimicrobial activity
(
MDPI
, 2021 , Article Review)
Lipid transfer proteins (LTPs) are among the most promising plant-exclusive antimicrobial peptides (AMPs). They figure among the most challenging AMPs from the point of view of their structural diversity, functions and ...
Biological Pathways Associated With the Development of Pulmonary Toxicities in Mesothelioma Patients Treated With Radical Hemithoracic Radiation Therapy: A Preliminary Study.
(
Frontiers Media
, 2021 , Article)
Radical hemithoracic radiotherapy (RHR), after lung-sparing surgery, has recently become a concrete therapeutic option for malignant pleural mesothelioma (MPM), an asbestos-related, highly aggressive tumor with increasing ...