Research Units: المرسلات الحديثة
السجلات المعروضة 1 -- 20 من 5639
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Exploiting transcription factors to target EMT and cancer stem cells for tumor modulation and therapy
( Elsevier , 2024 , Article)Transcription factors (TFs) are essential in controlling gene regulatory networks that determine cellular fate during embryogenesis and tumor development. TFs are the major players in promoting cancer stemness by regulating ... -
Deregulated transcription factors in the emerging cancer hallmarks
( Elsevier , 2024 , Article)Cancer progression is a multifaceted process that entails several stages and demands the persistent expression or activation of transcription factors (TFs) to facilitate growth and survival. TFs are a cluster of proteins ... -
Signaling networks guiding erythropoiesis
( Lippincott Williams and Wilkins , 2024 , Article Review)Purpose of reviewCytokine-mediated signaling pathways, including JAK/STAT, PI3K/AKT, and Ras/MAPK pathways, play an important role in the process of erythropoiesis. These pathways are involved in the survival, proliferation, ... -
Combining Gram stain and 16S qPCR improved diagnostic accuracy for suspected pneumonia and could become a new metric in the rapid diagnosis of lower respiratory tract infections
( Microbiology Society , 2024 , Article)Introduction. The frequency of multidrug-resistant organisms (MDROs) in hospitals and the risk of delaying effective treatment result in the culture of respiratory secretions for nearly all patients with suspected pneumonia. ... -
The cross-talk between miRNAs and JAK/STAT pathway in cutaneous T cell lymphoma: Emphasis on therapeutic opportunities
( Elsevier , 2024 , Article Review)Mycosis Fungoides (MF) and Sézary Syndrome (SS) belong to a wide spectrum of T cell lymphoproliferative disorders collectively termed cutaneous T cell lymphomas (CTCL). CTCLs represent an archetype of heterogeneous and ... -
Epigenetic control of inflammation in Atopic Dermatitis
( Elsevier , 2024 , Article Review)Atopic dermatitis (AD), also known as atopic eczema, is a common but also complex chronic, itchy skin condition with underlying inflammation of the skin. This skin ailment is prevalent worldwide and affects people of all ... -
Population-Based Norms for the Montreal Cognitive Assessment in Arab Adults
( John Wiley and Sons Ltd , 2025 , Article)Objective: The Montreal Cognitive Assessment (MoCA) is a brief screening instrument for detecting mild cognitive dysfunction, a precursor to many cognitive disorders, such as dementia, which have increased in prevalence ... -
Beyond nutrition: The emerging therapeutic potential landscape of breast milk-derived extracellular vesicles
( Elsevier , 2025 , Article)Breastfeeding is widely recognized for its essential nutritional benefits and broader biological impacts. Beyond providing infants with a balanced mix of vitamins, proteins, and fats critical for growth and development, ... -
Editorial: Experimental and computational methods in the development of diagnostics and therapeutics for colon cancer
( Frontiers Media SA , 2025 , Article)Cancer continues to be one of the major causes of illness and death worldwide. It is growing an alarming rate, and affects every geographic region of the world. Therefore, the goal is to investigate novel biomarkers both ... -
Understanding Heritable Variation Among Hosts in Infectious Diseases Through the Lens of Twin Studies
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article Review)Genetic factors have been hypothesized to contribute to the heterogeneity in the response to infectious diseases (IDs). The classical twin design provides a powerful tool to estimate the role of genetic contributions to ... -
The influence of circadian rhythm disruption during Ramadan on metabolic responses to physical activity: a pilot study
( Frontiers Media SA , 2025 , Article)Background: Circadian rhythms and sleep patterns are important regulators of metabolic health. During Ramadan intermittent fasting (RIF), the sleep–wake cycles are often disrupted, which can affect physical activity (PA) ... -
Chromosome-level reference genome assembly of the gyrfalcon (Falco rusticolus) and population genomics offer insights into the falcon population in Mongolia
( Nature Research , 2025 , Article)The taxonomic classification of a falcon population found in the Mongolian Altai region in Asia has been heavily debated for two centuries and previous studies have been inconclusive, hindering a more informed conservation ... -
Plant Coping with Cold Stress: Molecular and Physiological Adaptive Mechanisms with Future Perspectives
( MDPI , 2025 , Article Review)Cold stress strongly hinders plant growth and development. However, the molecular and physiological adaptive mechanisms of cold stress tolerance in plants are not well understood. Plants adopt several morpho-physiological ... -
Comparative metabolomics elucidates the early defense response mechanisms to Plutella xylostella infestation in Brassica napus
( Elsevier , 2025 , Article)Plutella xylostella (diamondback moth; DBM) is a significant pest of Brassica crops, causing billions of dollars in annual global damage and developing resistance to many insecticides. Climate change is increasing the ... -
Enhancing eggplant (Solanum melongena L.) yield and water use efficiency through optimized irrigation and nitrogen practices in open field conditions
( Elsevier , 2024 , Article)This study evaluated the interactive effects of deficit irrigation and nitrogen application on eggplant growth and yield under water scarcity in Northern Qatar (2022–2023). Two irrigation regimes were tested: full irrigation ... -
Isolation and Characterization of a Novel Silicate-Solubilizing Bacterial Strain Staphylococcus ureilyticus MV-1 Associated with Grape Wine
( Springer , 2025 , Article)This research aimed to isolate Staphylococcus ureilyticus MV-1 bacteria and evaluate their potential for soil application. These bacteria can solubilize silicate minerals up to 25 µg/mL in the first 10 h utilizing magnesium ... -
First report of serological, molecular detection, and characterization of human parvovirus B19 infections among sickle cell anaemia patients in Khartoum State, Sudan
( Elsevier , 2025 , Article)BackgroundPatients with haematological disorders, such as sickle cell anaemia, are at an elevated risk of transient aplastic crisis due to parvovirus B19 infection. The virus targets specific integration sites in the human ... -
Orf116b Induces Pollen Abortion in a Novel Cotton (Gossypium hirsutum L.) Cytoplasmic Male Sterile Line J4A
( MDPI , 2024 , Article)Cytoplasmic male sterile (CMS) systems have great potential in hybrid seed production in many plants. However, the incompatibility between the cytoplasmic and nuclear genes and the availability of fewer CMS lines limit the ... -
Nitrogen Deficiency Accelerates Rice Leaf Senescence Through ABA Signaling and Sugar Metabolic Shifts
( Wiley , 2025 , Article)Nitrogen (N) deficiency is one of the critical factors that induce leaf senescence by integrating with abscisic acid (ABA) metabolism, which results in a shortened leaf photosynthetic period and markedly lowered grain ... -
Study on application of green-synthesized ZnO and Si nanoparticles in enhancing aquaculture sediment quality
( Springer , 2025 , Article)Background: Fishpond sediments (FPS) are rich in organic carbon and nutrients, making them valuable as fertilizers and soil conditioners. Stabilizing heavy metals like chromium (Cr), copper (Cu), and zinc (Zn) is essential ...
