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AuthorLuka, George
AuthorAhmadi, Ali
AuthorNajjaran, Homayoun
AuthorAlocilja, Evangelyn
AuthorDeRosa, Maria
AuthorWolthers, Kirsten
AuthorMalki, Ahmed
AuthorAziz, Hassan
AuthorAlthani, Asmaa
AuthorHoorfar, Mina
Available date2015-11-04T20:06:42Z
Publication Date2015-12
Publication NameSensors
CitationLuka, G., Ahmadi, A., Najjaran, H., Alocilja, E., DeRosa, M., Wolthers, K., Malki, A., Aziz, H., Althani, A., Hoorfar, M. (2015), "Microfluidics integrated biosensors: A leading technology towards lab-on-a-chip and sensing applications", Sensors, 15(12): 30011–30031
ISSN1424-8220
URIhttp://hdl.handle.net/10576/3626
URIhttp://dx.doi.org/10.3390/s151229783
AbstractA biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. Microfluidic systems, on the other hand, provide throughput processing, enhance transport for controlling the flow conditions, increase the mixing rate of different reagents, reduce sample and reagents volume (down to nanoliter), increase sensitivity of detection, and utilize the same platform for both sample preparation and detection. In view of these advantages, the integration of microfluidic and biosensor technologies provides the ability to merge chemical and biological components into a single platform and offers new opportunities for future biosensing applications including portability, disposability, real-time detection, unprecedented accuracies, and simultaneous analysis of different analytes in a single device. This review aims to represent advances and achievements in the field of microfluidic-based biosensing. The review also presents examples extracted from the literature to demonstrate the advantages of merging microfluidic and biosensing technologies and illustrate the versatility that such integration promises in the future biosensing for emerging areas of biological engineering, biomedical studies, point-of-care diagnostics, environmental monitoring, and precision agriculture.
SponsorNatural Sciences and Engineering Research Council of Canada (NSERC) and India-Canada Centre for Innovative Multidisciplinary Partnerships to Accelerate Community Transformation & Sustainability (IC-IMPACTS)
Languageen
PublisherMultidisciplinary Digital Publishing Institute (MDPI)
SubjectMicrofluidic
biosensor
lab-on-a-chip
microfluidic-based biosensor
Micro total analysis systems (μTAS)
TitleMicrofluidics integrated biosensors: A leading technology towards lab-on-a-chip and sensing applications
TypeArticle
Pagination30011–30031
Issue Number12
Volume Number15
dc.accessType Open Access


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