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AuthorFernandes, Queenie
AuthorAllouch, Soumaya
AuthorGupta, Ishita
AuthorElmakaty, Ibrahim
AuthorElzawawi, Khaled E
AuthorAmarah, Ahmed
AuthorAl-Thawadi, Hamda
AuthorAl-Farsi, Halema
AuthorVranic, Semir
AuthorAl Moustafa, Ala-Eddin
Available date2022-11-28T06:03:00Z
Publication Date2022-11-19
Publication NamePathogens
Identifierhttp://dx.doi.org/10.3390/pathogens11111380
CitationFernandes, Q.; Allouch, S.; Gupta, I.; Elmakaty, I.; Elzawawi, K.E.; Amarah, A.; Al-Thawadi, H.; Al-Farsi, H.; Vranic, S.; Al Moustafa, A.-E. Human Papillomaviruses-Related Cancers: An Update on the Presence and Prevention Strategies in the Middle East and North African Regions. Pathogens 2022, 11, 1380. https://doi.org/10.3390/pathogens11111380
URIhttp://hdl.handle.net/10576/36731
AbstractThe human papillomavirus (HPV) is a non-enveloped double-stranded DNA virus capable of infecting skin and mucosa epithelial cells. Commonly, HPV infection is associated with sexually transmitted diseases and is considered the leading cause of cervical cancer and other carcinomas of the anogenital tract. However, several studies reported their involvement in cancers of non-sexual regions, including colorectal, head and neck, and breast cancers. There are several studies from the Middle East and North Africa (MENA) regions on the potential association between high-risk HPVs and cancer; nevertheless, there are limited studies that address the significance of HPV vaccination as a potential guard against these cancers. In the current review, we present a comprehensive description of the current HPV-associated cancers prevalence rates in the MENA region, demonstrating their steady increase with time, especially in African regions. Moreover, we discuss the potential impact of vaccination against HPV infections and its outcome on human health in this region.
SponsorOur lab is supported by grants from Qatar University: QUCP-CMED-2021-1 and QUCP-CMED-2022/23-529.
Languageen
PublisherMDPI
Subjectbreast cancer
cervical cancer
colorectal cancer
head and neck cancer
human papillomaviruses
the Middle East and North African region
TitleHuman Papillomaviruses-Related Cancers: An Update on the Presence and Prevention Strategies in the Middle East and North African Regions.
TypeArticle Review
Issue Number11
Volume Number11
ESSN2076-0817
dc.accessType Open Access


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