Electrochemical Analysis of Sulfisoxazole Using Glassy Carbon Electrode (GCE) and MWCNTs/Rare Earth Oxide (CeO2 and Yb2O3) Modified-GCE Sensors
Author | El-Azazy, Marwa |
Author | Ahsan, Insharah |
Author | Bensalah, Nasr |
Available date | 2022-12-11T04:01:15Z |
Publication Date | 2022-03-21 |
Publication Name | Molecules |
Identifier | http://dx.doi.org/10.3390/molecules27062033 |
Citation | El-Azazy, M., Ahsan, I., & Bensalah, N. (2022). Electrochemical Analysis of Sulfisoxazole Using Glassy Carbon Electrode (GCE) and MWCNTs/Rare Earth Oxide (CeO2 and Yb2O3) Modified-GCE Sensors. Molecules, 27(6), 2033. |
ISSN | 1420-3049 |
Abstract | In this work, new electrochemical sensors based on the modification of glassy carbon electrode (GCE) with multiwalled carbon nanotubes (MWCNTs)—rare metal oxides (REMO) nanocomposites were fabricated by drop-to-drop method of MWCNTs-REMO dispersion in ethanol. REMO nanoparticles were synthesized by precipitation followed by hydrothermal treatment at 180◦C in absence and presence of Triton™ X-100 surfactant. Cyclic voltammetry (CV) analysis using MWCNTs-CeO2@GCE and MWCNTs-Yb2O3@GCE sensors were used for the analysis of sulfisoxazole (SFX) drug in water samples. The results of CV analysis showed that MWCNTs-REMO@GCE sensors have up to 40-fold higher sensitivity with CeO2 compared to the bare GCE sensor. The estimated values of the limit of detection (LoD) of this electrochemical sensing using MWCNTs-CeO2@GCE and MWCNTs-Yb2O3@GCE electrodes reached 0.4 and 0.7 µM SFX in phosphate buffer pH = 7, respectively. These findings indicate that MWCNTs-REMO@GCE electrodes are potential sensors for analysis of sulfonamide drugs in water and biological samples. |
Sponsor | Qatar University Internal Student Grant - No. QUST-1-CAS-2022-338 |
Language | en |
Publisher | MDPI |
Subject | electroanalysis limit of detection modified electrode multiwalled carbon nanotubes (MWCNTs) peak current rare earth metal oxides (REMO) sulfisoxazole |
Type | Article |
Issue Number | 6 |
Volume Number | 27 |
ESSN | 1420-3049 |
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