Show simple item record

AuthorJatau, Abubakar Ibrahim
AuthorShitu, Zayyanu
AuthorKhalid, Garba Mohammed
AuthorYunusa, Ismaeel
AuthorAwaisu, Ahmed
Available date2022-12-15T07:16:24Z
Publication Date2019
Publication NameTherapeutic Advances in Drug Safety
ResourceScopus
URIhttp://dx.doi.org/10.1177/2042098619852552
URIhttp://hdl.handle.net/10576/37332
AbstractBackground: The burden of adverse drug event (ADE)-related emergency department (ED) visits is increasing despite several preventive measures. The objective of this paper was to develop and validate a conceptual model for a better understanding of ADE-related ED visits and to guide the design and implementation of effective interventions. Methods: The development of the model involved a systematic review of the literature using PubMed and Embase databases. Studies reporting the risk factors associated with ADE-related ED visits were included. The methodological qualities of the included studies were assessed using the Mixed Methods Appraisal Tool (MMAT). The model was mapped and validated using face and content validity by an expert panel. Deficiencies and targeted interventions were identified, and steps for the design and implementation were recommended. Results: The literature search generated 1361 articles, of which 38 were included in the review; 41 risk factors associated with ADE-related ED visits were identified. All factors were mapped, and the model was validated through face and content validity. The model consisted of six concepts related to sociodemographic factors, clinical factors, ADE-related to ED visits, ADE while in the ED, outcomes, and consequences. Interventions could be targeted at the factors identified in each concept to prevent ADE-related ED burden. Conclusion: A conceptual model to guide the successful design and implementation of strategies to prevent ADE-related ED visits and the occurrence of ADE at ED was developed. Clinicians should take these factors into consideration to prevent untoward events, especially when treating high-risk patients. The Author(s), 2019.
SponsorADE: adverse drug event; ED: emergency department; NHAMCS: National Hospital Ambulatory Medical Care Survey; NESARC: National Epidemiology Survey on Alcohol and Related Conditions; NEISS-CADES: National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance project; CVS: cardiovascular system; AHCA: Agency for Health Care Administration; RAS: renin-angiotensin system; NSAIDS: nonsteroidal anti-inflammatory drugs; ACE: angiotensin-converting-enzyme; NEISS: National Electronic Injury Surveillance System; US United States; NR: not reported. aNational Health and Medical Research Council level of evidence. bMixed Methods Appraisal Tool score.
Languageen
PublisherSAGE Publications Ltd
SubjectAdverse drug events
Drug-related problem
Emergency department
Pharmacoepidemiology
TitleUnderstanding adverse drug-related emergency department visits: Development of a conceptual model through a systematic review
TypeArticle Review
Pagination18-Jan
Volume Number10


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record