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Haematological abnormalities and risk of covid-19 infection in adult patients attending primary healthcare settings
( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Centres for Disease Control and prevention (CDC) reports that there are limited data and information about the impact of underlying medical conditions and the risk of infection. To date, there are no studies that report ... -
Corrigendum to "Periprocedural Anticoagulation Management of Patients receiving Warfarin in Qatar: A Prospective Cohort Study". [Current Problems in Cardiology Volume 46, Issue 6, June 2021, 100816]
( Elsevier , 2021 , Article)Authors regret an affiliation was missed for Dr. Nabil Shallik in the original version. The affiliation "Faculty of Medicine, Tanta University, Tanta, Egypt" has now been added. And also the order of authors has been ... -
Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits
( Springer Nature , 2021 , Article)Clinical laboratory tests play a pivotal role in medical decision making, but little is known about their genetic variability between populations. We report a genome-wide association study with 45 clinically relevant traits ... -
Peri-renal adipose inflammation contributes to renal dysfunction in a non-obese prediabetic rat model: Role of anti-diabetic drugs
( Elsevier , 2021 , Article)Diabetic nephropathy is a major health challenge with considerable economic burden and significant impact on patients’ quality of life. Despite recent advances in diabetic patient care, current clinical practice guidelines ... -
Protein glycation – biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine
( Elsevier , 2021 , Article)Protein glycation provides a biomarker in widespread clinical use, glycated hemoglobin HbA1c (A1C). It is a biomarker for diagnosis of diabetes and prediabetes and of medium-term glycemic control in patients with established ... -
Metal-based nanoparticles: Promising tools for the management of cardiovascular diseases
( Elsevier , 2021 , Article)Cardiovascular disease (CVD) is the leading cause of death worldwide. A search for more effective treatments of CVD is increasingly needed. Major advances in nanotechnology opened new avenues in CVD therapeutics. Owing to ... -
Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress-impaired endothelial cell angiogenic response: A critical role for cell survival
( Spandidos publications , 2021 , Article)Endoplasmic reticulum (ER) stress contributes to endothelial dysfunction, which is the initial step in atherogenesis. Blockade of protein tyrosine phosphatase (PTP)1B, a negative regulator of insulin receptors that is ... -
Modulation of preeclampsia by the cholinergic anti-inflammatory pathway: Therapeutic perspectives
( Elsevier , 2021 , Article Review)The cholinergic anti-inflammatory pathway (CAP) is vital for the orchestration of the immune and inflammatory responses under normal and challenged conditions. Over the past two decades, peripheral and central circuits of ... -
The Effect of Chronic Endurance Exercise on Serum Levels of MOTS-c and Humanin in Professional Athletes
( IMR Press Limited , 2022 , Article)Background: Humanin and the mitochondrial open reading frame of the 12S rRNA-c (MOTS-c) are mitochondrial encoded peptides involved in energy metabolism, cytoprotection, longevity, insulin sensitivity and their expression ... -
Common indications for Referral to the Healthcare system for COVID-19 recovered patients versus Qatar Biobank study population: A descriptive analysis
( Mattioli1885 , 2022 , Article)Background and Aim of the Work: Qatar Biobank (QBB) is actively acquiring data on the range of short-and long-term health impacts associated with COVID-19. This is performed through the COVID-19 biorepository National ... -
mRNA-based COVID-19 Vaccines Booster Dose: BenefitRisks, and Coverage
( Mattioli1885 , 2022 , Article)The number of COVID-19 vaccine-rich countries that have started COVID-19 third-dose booster programs is growing dramatically despite the lack of robust evidence on the effectiveness, safety, and frequency of the required ... -
Exploring challenges and mitigation strategies towards practicing Teledentistry
( BioMed Central Ltd , 2022 , Article)Background: Since the beginning of the COVID-19 pandemic, many dentists have opted for Teledentistry as a mechanism for patient consultation, oral lesion evaluation, diagnosis, and monitoring. The current study explores ... -
Natural resorcylic acid lactones: A chemical biology approach for anticancer activity
( Elsevier , 2022 , Article)Resorcylic acid lactones (RALs) are fungal polyketides that consist of a β-resorcylic acid residue (2,4-dihydroxybenzoic acid) embedded in a macrolactone ring. RALs exhibit a broad range of biological activities, including ... -
Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells
( Elsevier , 2022 , Article)Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by ... -
Enteric pathogens modulate metabolic homeostasis in the Drosophila melanogaster host
( Elsevier , 2022 , Article)On quotidian basis, living beings work out an armistice with their microbial flora and a scuffle with invading pathogens to maintain a normal state of health. Although producing virulence factors and escaping the host's ... -
Nano-targeting vascular remodeling in cancer: Recent developments and future directions
( Elsevier , 2022 , Article Review)Tumor growth and progression are strictly dependent on the adequate blood supply of oxygen and nutrients. The formation of new blood vessels and vascular networks is essential to ensure this demand. Blood vessels also ... -
The impact of digital interventions on medication adherence in paediatric populations with attention deficit hyperactivity disorder, depression, and/or anxiety: A rapid systematic review and meta-analysis
( Elsevier , 2022 , Article Review)BackgroundThe growing prevalence of mental health disorders in children and adolescents coupled with poor medication adherence in the paediatric population is a major problem within healthcare systems affecting patient ... -
Psychometric Properties and Assessment of Knowledge, Attitude, and Practice Towards ChatGPT in Pharmacy Practice and Education: a Study Protocol
( Springer Science and Business Media Deutschland GmbH , 2023 , Article)ChatGPT represents an advanced conversational artificial intelligence (AI), providing a powerful tool for generating human-like responses that could change pharmacy prospects. This protocol aims to describe the development, ... -
Exploring the effects of health behaviors and mental health on students' academic achievement: a cross-sectional study on lebanese university students
( BioMed Central Ltd , 2023 , Article)Background High academic achievement, an important determinant of future success, is known to be influenced by many factors including dietary behavior, lifestyle and mental health, among others. The objectives of the ... -
Novel SPEA Superantigen Peptide Agonists and Peptide Agonist-TGFαL3 Conjugate. In Vitro Study of Their Growth-Inhibitory Effects for Targeted Cancer Immunotherapy
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Bacterial superantigens (SAgs) are effective T-cell stimulatory molecules that lead to massive cytokine production. Superantigens crosslink between MHC class II molecules on the Antigen Presenting Cells (APC) and TCR on ...
