Algae-derived bioactive compounds with anti-lung cancer potential
Author | Saadaoui, Imen |
Author | Rasheed, Rihab |
Author | Abdulrahman, Nabeel |
Author | Bounnit, Touria |
Author | Cherif, Maroua |
Author | Al Jabri, Hareb |
Author | Mraiche, Fatima |
Available date | 2023-02-20T04:49:43Z |
Publication Date | 2020-01-01 |
Publication Name | Marine Drugs |
Identifier | http://dx.doi.org/10.3390/md18040197 |
Citation | Saadaoui, I.; Rasheed, R.; Abdulrahman, N.; Bounnit, T.; Cherif, M.; Al Jabri, H.; Mraiche, F. Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential. Mar. Drugs 2020, 18, 197. https://doi.org/10.3390/md18040197 |
Abstract | Lung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of the conventional drugs. Recently, algae as source of high value-added compounds are considered as very promising source of these bioactive molecules. These are secondary metabolites that consist mainly of derivatives of peptides, carbohydrates, and lipids with various structures. Accordingly, various mechanisms by which different algae molecules demonstrate attenuation of tumor angiogenesis were stated and discussed. The mode of action of the algae bioactives is closely related to their nature and chemical structure. Furthermore, this literature review considers the synergistic effect between microalgae bioactives and conventional drugs and discuss the economic feasibility of producing microalgae bioactives at large scale to conclude with some future perspectives related to algae-based drug discovery. |
Sponsor | This research was funded by Qatar National Research Fund, grant number “NPRP8-1087-1-207”. |
Language | en |
Publisher | MDPI |
Subject | Bioactives Drug discovery Lung cancer Marine algae Mode of action Molecular target |
Type | Article Review |
Issue Number | 4 |
Volume Number | 18 |
ESSN | 1660-3397 |
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Center for Sustainable Development Research [317 items ]
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