تصفح Central Laboratories Unit Research حسب المؤلف "Haque, Anzarul"
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Development of novel nanoemulsion of pioglitazone used in the treatment of diabetes and its gel form for the treatment of skin diseases
Niyaz, Ahmad; Ansari, Khalid; Alamoudi, Mariam K.; Ullah, Zabih; Haque, Anzarul; Ibrahim, Hisham Osman... more authors ... less authors ( Elsevier , 2024 , Article)Pioglitazone (PGL), an antidiabetic drug within the thiazolidinedione class, is utilized in managing type-2-diabetes-mellitus. Additionally, it has been observed to exhibit therapeutic effects on various inflammatory ... -
Eco-friendly green synthesis of silver nanoparticles utilizing olive oil waste by-product and their incorporation into a chitosan-aloe vera gel composite for enhanced wound healing in acid burn injuries
Basel A., Abdel-Wahab; Haque, Anzarul; Faris Alotaibi, Hadil; Alasiri, Ali S.; AE Elnoubi, Osman; Zaki Ahmad, Mohammad; Pathak, Kalyani; Albarqi, Hassan A.; Walbi, Ismail A.; Wahab, Shadma... more authors ... less authors ( Elsevier , 2024 , Other)This study focused on the green synthesis of silver nanoparticles (AgNPs) using olive oil waste by-product and their incorporation into Chitosan-Aloe-Vera gel (AgNPs/AV-CS gel). The synthesized AgNPs exhibited a hydrodynamic ... -
In-Vitro Dissolution Study of Solid Dispersion Adsorbate of Nateglinide by Eco-Friendly Liquid Chromatography-Tandem Mass Spectrometric Method through Harmonized Approach of White Analytical Chemistry and Analytical Quality by Design
Prajapati, Pintu; Dhameliya, Rutvik; Jha, Rahul; Shah, Pranav; Pulusu, Veera Shakar; Haque, Anzarul; Ahmad, Sarfaraz; Shah, Shailesh... more authors ... less authors ( Springer Nature , 2024 , Article)Purpose: Nateglinide, a member of the meglitinide class, is used as an oral antihyperglycemic agent to treat non-insulin-dependent diabetes mellitus. It falls under the BCS class II category and has a low solubility ... -
In-vivo pharmacokinetic study of ibrutinib-loaded nanostructured lipid carriers in rat plasma by sensitive spectrofluorimetric method using harmonized approach of quality by design and white analytical chemistry
Pintu, Prajapati; Patel, Anjali; Desai, Aneri; Shah, Pranav; Pulusu, Veera Shakar; Haque, Anzarul; Kalam, Mohd Abul; Shah, Shailesh... more authors ... less authors ( Elsevier , 2024 , Article)Ibrutinib, an antineoplastic agent tackling chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom’s Macroglobulinemia, falls under the category of BCS class II drugs, characterized by a puzzling combination ... -
Integrated approach of white analytical chemistry and design of experiments to microwave-assisted sensitive and eco-friendly spectrofluorimetric estimation of mirabegron using 4-chloro-7-nitrobezofuran as biosensing fluorescent probe
Pintu, Prajapati; Patel, Krishna; Patel, Ankita; Shakar Pulusu, Veera; Haque, Anzarul; Ahmad, Sarfaraz; Shah, Shailesh... more authors ... less authors ( Elsevier , 2024 , Article)The USFDA recently approved mirabegron, a novel once-daily β-3 adrenoceptor agonist for oral administration, as a transformative treatment for overactive bladder. Despite the existence of numerous analytical methods for ... -
A novel mucoadhesive paliperidone-nanoemulsion developed using the ultrasonication method in the treatment of schizophrenia
Ahmad, Niyaz; Ansari, Khalid; Alamoudi, Mariam K.; Haque, Anzarul; Ullah, Zabih; Khalid, Mohammed Saifuddin; Ahmad, Sarfaraz... more authors ... less authors ( Royal Society of Chemistry , 2024 , Article)Aim: To develop paliperidone mucoadhesive-nanoemulsion (PLP-NE) to enhance brain bioavailability. To evaluate comparative effects of PLP-NE and CS-PLP-NE in the treatment of schizophrenia, followed by a toxicity study of ... -
Significance of Triazole in Medicinal Chemistry: Advancement in Drug Design, Reward and Biological Activity.
Ajmal, Mohammad; Mahato, Arun Kumar; Khan, Mausin; Rawat, Shivani; Husain, Asif; Almalki, Emad Bakheet; Alzahrani, Mohammed Ahmed; Haque, Anzarul; Hakme, Mohammed Japer Mohammed; Albalawi, Ahmed Suleman; Rashid, Mohd... more authors ... less authors ( Wiley , 2024 , Article Review)One of the triazole tautomers, 1,2,4-triazole derivatives, has a wide range of biological activities that suggest its potential therapeutic utility in medicinal chemistry. These actions include anti-inflammatory, anti-cancer, ... -
Targeting protein receptors and enzymes for precision management of urolithiasis: A comprehensive review
Ziyaul, Haque; Taleuzzaman, Mohamad; Jamal, Ruqaiya; Al-Qahtani, Noora H.; Haque, Anzarul ( Elsevier , 2024 , Article)Urolithiasis, characterized by the formation of solid crystalline structures within the urinary tract, presents a significant global health burden with high recurrence rates and limited treatment efficacy. Recent research ...