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AuthorMasoudkabir, Farzad
AuthorMalekzadeh, Reza
AuthorYavari, Negin
AuthorZendehdel, Kazem
AuthorMani, Arya
AuthorVasheghani-Farahani, Ali
AuthorIgnaszewski, Andrew
AuthorToma, Mustafa
AuthorRoayaei, Pegah
AuthorTurk-Adawi, Karam
AuthorSarrafzadegan, Nizal
Available date2023-03-26T09:31:41Z
Publication Date2022-01
Publication NameArchives of Iranian Medicine
Identifierhttp://dx.doi.org/10.34172/AIM.2022.08
CitationMasoudkabir, F., Malekzadeh, R., Yavari, N., Zendehdel, K., Mani, A., Vasheghani-Farahani, A., ... & Sarrafzadegan, N. (2022). Does opium consumption have shared impact on atherosclerotic cardiovascular disease and cancer?. Archives of Iranian Medicine, 25(1), 50-63.
ISSN1029-2977
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85124184799&origin=inward
URIhttp://hdl.handle.net/10576/41322
AbstractAlthough atherosclerotic cardiovascular disease (ASCVD) and cancer are seemingly different types of disease, they have multiple shared underlying mechanisms and lifestyle-related risk factors like smoking, unhealthy diet, excessive alcohol consumption, and inadequate physical activity. Opium abuse is prevalent in developing countries, especially the Middle East region and many Asian countries. Besides recreational purposes, many people use opium based on a traditional belief that opium consumption may confer protection against heart attack and improve the control of the risk factors of ASCVD such as diabetes mellitus, hypertension, and dyslipidemia. However, scientific reports indicate an increased risk of ASCVD and poor control of ASCVD risk factors among opium abusers compared with nonusers. Moreover, there is accumulating evidence that opium consumption exerts potential carcinogenic effects and increases the risk of developing various types of cancer. We conducted a review of the literature to review the current evidence on the relationship between opium consumption and ASCVD as well as various kinds of cancer. In addition, we will discuss the potential shared pathophysiologic mechanisms underlying the association between opium abuse and both ASCVD and cancer.
Languageen
PublisherAcademy of Medical Sciences of I.R. Iran
SubjectAtherosclerosis
Cancer
Coronary artery disease
Opium
Tumor
TitleDoes Opium Consumption Have Shared Impact on Atherosclerotic Cardiovascular Disease and Cancer?
TypeArticle
Pagination50-63
Issue Number1
Volume Number25
ESSN1735-3947
dc.accessType Abstract Only


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