College of Medicine: المرسلات الحديثة
السجلات المعروضة 1201 -- 1220 من 1449
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Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?
( Springer New York LLC , 2019 , Article)Background: Obesity is a risk for many different cancers. Laparoscopic sleeve gastrectomy (LSG) is common, and benign or pre-malignant histopathology types are reported in the removed gastric specimens. We assessed whether ... -
In honour of Professor Patrick Couvreur, recipient of the Journal Of Drug Targeting’s Lifetime Achievement Award For 2019
( Taylor and Francis Ltd , 2019 , Other)[No abstract available] -
Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity
( Elsevier Ltd , 2019 , Article)The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally ... -
Gallbladder cancer: 7-Year experience from Qatar
( Elsevier Ltd , 2019 , Article)Thirty-five patients presented with GC during the study period, 10 females (28.6%) and 25 males (71.4%). Fourteen patients (40%) were diagnosed incidentally after laparoscopic cholecystectomy, 16 (48.6%) were diagnosed ... -
The vascular glycocalyx is not a mechanosensor in conduit arteries in the anesthetized pig.
( PeerJ , 2020 , Article)The role of the glycocalyx as the endothelial sensor of an increase in blood flow was assessed in the iliac artery in vivo. Acetylcholine-induced flow mediated dilation was evaluated before and after vascular glycocalyx ... -
Human Papillomaviruses and Epstein-Barr Virus Interactions in Colorectal Cancer: A Brief Review.
( MDPI , 2020 , Article)Human papillomaviruses (HPVs) and the Epstein-Barr virus (EBV) are the most common oncoviruses, contributing to approximately 10%-15% of all malignancies. Oncoproteins of high-risk HPVs (E5 and E6/E7), as well as EBV (LMP1, ... -
Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats.
( Public Library of Science , 2020 , Article)Oxidative stress is involved in the pathogenesis of a number of diseases including hypertension and renal failure. There is enhanced expression of nicotinamide adenine dinucleotide (NADPH oxidase) and therefore production ... -
DNA Damage/Repair Management in Cancers
( MDPI , 2020 , Article Review)DNA damage is well recognized as a critical factor in cancer development and progression. DNA lesions create an abnormal nucleotide or nucleotide fragment, causing a break in one or both chains of the DNA strand. When DNA ... -
Quality, safety and efficiency in practice: Risk assessment and standardisation of anesthesia equipment and supplies in operating theaters of high-volume tertiary-care academic medical center
( American University of Beirut , 2019 , Article)Background: Operating theatres (OTs) are valuable and costly resources that need to be appropriately designed and stocked for efficient, quality and safe patient care. We assessed the logistic inefficiency including the ... -
Vitamin D for the Immune System in Cystic Fibrosis (DISC): A double-blind, multicenter, randomized, placebo-controlled clinical trial
( Oxford University Press , 2019 , Article)Background Patients with cystic fibrosis (CF) have increased risk of vitamin D deficiency owing to fat malabsorption and other factors. Vitamin D deficiency has been associated with increased risk of pulmonary exacerbations ... -
Lorcaserin vs. Phentermine among non-surgical and surgical obese patients: Anthropometric, glycemic, lipid, safety and cost outcomes
( Elsevier Ltd , 2019 , Article)Background To evaluate effectiveness, safety, and costs of Lorcaserin vs. phentermine among obese non–surgical and surgical patients (post bariatric surgery). Methods This retrospective study retrieved charts of all ... -
Safety and efficacy of leadless pacemaker retrieval
( Blackwell Publishing Inc. , 2019 , Article Review)Background and Objectives: The success rate of leadless cardiac pacemaker (LP) retrieval remains a major concern for this disruptive technology. The present paper performed a systematic review of the safety and feasibility ... -
Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function.
( Oxford University Press , 2020 , Article)The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca2+ release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. This study was ... -
Investigating the blood-host plasticity and dispersal of Anopheles coluzzii using a novel field-based methodology
( BioMed Central Ltd. , 2019 , Article)Background: The biting behaviour and dispersal of insect vectors in the field underlies the transmission of many diseases. Here, a novel collection methodology coupled with the molecular analysis of blood-meal sources and ... -
Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis
( Blackwell Publishing Ltd , 2019 , Article)Background When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular hypoxia. The hypoxia‐inducible ... -
Long-term in vivo study of biodegradable Zn-Cu stent: A 2-year implantation evaluation in porcine coronary artery
( Acta Materialia Inc , 2019 , Article)In the present study, a novel biodegradable Zn-0.8Cu coronary artery stent was fabricated and implanted into porcine coronary arteries for up to 24 months. Micro-CT analysis showed that the implanted stent was able to ... -
Lichen planus: a comprehensive evidence-based analysis of medical treatment
( Blackwell Publishing Ltd , 2019 , Article Review)Lichen planus (LP) is a chronic-relapsing inflammatory skin disease. Although many drugs have been used for the management of LP, some of them lack the backup by strong therapeutic evidence, while others are not suitable ... -
Novel targetable biomarkers in clear cell carcinoma of the breast uncovered by molecular profiling: A study of nine cases.
( Wiley , 2020 , Article)We profiled nine pure clear cell carcinomas of the breast using massively parallel DNA and RNA sequencing (NGS), in situ hybridization (ISH), and immunohistochemistry (IHC). All cases were primary mammary clear cell ... -
Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation: Meta-analysis of Safety and Efficacy
( NLM (Medline) , 2019 , Article)BACKGROUND: Radiofrequency ablation (RFA) and antiarrhythmic drugs (AADs) are the main treatments used for atrial fibrillation (AF). In recent years, a number of articles comparing the 2 treatments have begun to emerge. ... -
Pentalogy of cantrell
( Jaypee Brothers Medical Publishers (P) Ltd , 2019 , Article)[No abstract available]