College of Medicine: Recent submissions
Now showing items 861-880 of 1448
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Pyridoxine non-responsive p.R336C mutation alters the molecular properties of cystathionine beta-synthase leading to severe homocystinuria phenotype
( Elsevier , 2022 , Article)The prevalence of homocystinuria in Qatar is 1:1800, mainly due to a founder missense mutation p.R336C. • The cystathionine beta-synthase (CBS) R336C mutant was bacterially expressed, purified and its molecular properties ... -
Mechanisms underlying the effects of caloric restriction on hypertension
( Elsevier , 2022 , Article)Hypertension is a major risk factor for cardiovascular disease (CVD) as well as a major contributor to all-cause mortality and disability worldwide. The pathophysiology of hypertension is highly attributed to a dysfunctional ... -
Thrombin generation measured on ST Genesia, a new platform in the coagulation routine lab: Assessment of analytical and between-subject variation
( Wiley Open Access , 2022 , Article)Background: The thrombin generation (TG) assay, which measures global coagulation, has mainly been used as a research tool to investigate thrombotic and bleeding disorders. Recently, Diagnostica Stago launched the ST ... -
Driver Drowsiness Detection Study using Heart Rate Variability analysis in Virtual Reality Environment
( Hamad bin Khalifa University Press (HBKU Press) , 2018 , Conference Paper)Introduction Mobility and road safety is one of the grand challenges that Qatar is facing during the last decade. There are many ways to enhance the road safety. One way is to characterize the factors contributing to the ... -
The expansion of soil-transmitted helminth control strategies ? Authors' reply
( Lancet Publishing Group , 2017 , Article)[No abstract available] -
25-Hydroxyvitamin D Concentrations and Clostridium difficile Infection: A Meta-Analysis
( SAGE Publications Inc. , 2017 , Article)Background: Well-known risk factors for Clostridium difficile infection (CDI) are exposure to antibiotics and gastric acid suppressants. Recent studies have provided some evidence of an association between hypovitaminosis ... -
The coincidence of increased risk of atrial fibrillation in randomized control trials of omega-3 fatty acids: a meta-analysis
( Taylor and Francis Ltd. , 2021 , Article)[No abstract available] -
Towards a better understanding of self-management interventions in type 2 diabetes: A meta-regression analysis
( Elsevier Ltd , 2021 , Article)Aims: Attributes that operationally conceptualize diabetes self-management education (DSME) interventions have never been studied previously to assess their impact on relevant outcomes of interest in people with type 2 ... -
Albumin administration in patients with decompensated liver cirrhosis: A meta-analytic update
( Lippincott Williams and Wilkins , 2021 , Article Review)End-stage liver disease and its related complications exert a huge disease burden and reduce the survival rates of many patients. Albumin administration for patients with decompensated liver cirrhosis has been a controversial ... -
The effectiveness of targeted relative to empiric prophylaxis on infectious complications after transrectal ultrasound-guided prostate biopsy: a meta-analysis
( Springer Verlag , 2018 , Article Review)Purpose: Rectal culture screening for fluoroquinolone (FQ)-resistant Enterobacteriaceae before transrectal ultrasound guided prostate (TRUSPB) biopsy and targeted antibiotic prophylaxis (TAP) may decrease post-TRUSPB ... -
Pharmacotherapy in COVID-19 patients: a review of ACE2-raising drugs and their clinical safety
( Taylor and Francis Ltd , 2020 , Article Review)The COVID-19 pandemic is caused by the severe acute-respiratory-syndrome-coronavirus-2 that uses ACE2 as its receptor. Drugs that raise serum/tissue ACE2 levels include ACE inhibitors (ACEIs) and angiotensin-II receptor ... -
Flight Versus Ground Out-of-hospital Rapid Sequence Intubation Success: a Systematic Review and Meta-analysis
( Taylor and Francis Ltd , 2018 , Article)Introduction: Endotracheal intubation (ETI) is a critical procedure performed by both air medical and ground based emergency medical services (EMS). Previous work has suggested that ETI success rates are greater for air ... -
An evidence base for school health policy during the covid-19 pandemic
( Paris Scholar Publishing , 2021 , Article)Objective: Children represent a small fraction of confirmed COVID-19 cases, with a low case fatality rate (CFR). In this paper, we lay out an evidence-based policy for reopening schools. Methods: We gathered age-specific ... -
Diagnostic accuracy of ELISA kits for measurement of rabies antibodies
( NLM (Medline) , 2021 , Article)[No abstract available] -
Research Methods for Zero Event Proportion Studies: The Incidence of Bleeding After Thoracentesis and Tube Thoracostomy in Patients With Uncorrected Coagulopathy
( Elsevier Inc. , 2021 , Article)In a recent meta-analysis published in CHEST (November 2021), Fong et al1 investigated the incidence of bleeding after thoracentesis and tube thoracostomy in patients with uncorrected coagulopathy. The authors used the ... -
Development and Validation of an Early Scoring System for Prediction of Disease Severity in COVID-19 Using Complete Blood Count Parameters
( Institute of Electrical and Electronics Engineers Inc. , 2021 , Article)The coronavirus disease 2019 (COVID-19) after outbreaking in Wuhan increasingly spread throughout the world. Fast, reliable, and easily accessible clinical assessment of the severity of the disease can help in allocating ... -
Reply to: Let us not rush back to odds ratios in meta-analysis
( Elsevier Inc. , 2021 , Article)[No abstract available] -
The MethodologicAl STandards for Epidemiological Research (MASTER) scale demonstrated a unified framework for bias assessment
( Elsevier Inc. , 2021 , Article)Objective: This paper presents a unified framework for assessment of the methodological quality of analytic study designs. Study Design and Setting: A systematic review of 393 methodological quality assessment tools that ... -
Core outcomes in gestational diabetes for treatment trials: The Gestational Metabolic Group treatment set
( John Wiley and Sons Inc , 2021 , Article)Aims With the rising number of outcomes being reported following gestational diabetes (GDM), the outcomes in existing studies vary widely making it challenging to compare and contrast the effectiveness of different ... -
A review of breast cancer pathology reports in Nigeria
( ecancer Global Foundation , 2021 , Article Review)Background: Diagnosis and treatment of cancer rely heavily on imaging, histopathology and molecular information. Incomplete or missing tumour information can hinder the delivery of high-quality care in oncology practice, ...