College of Pharmacy: المرسلات الحديثة
السجلات المعروضة 501 -- 520 من 1314
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Genomewide association analysis of warfarin dose requirements in Middle Eastern and North African populations
( Wiley-Blackwell , 2022 , Article)To date, there has been no genomewide association study (GWAS) from the Middle East and North African (MENA) region to identify genetic variants associated with warfarin dose variability using this approach. In this study, ... -
Norfloxacin loaded lipid polymer hybrid nanoparticles for oral administration: Fabrication, characterization, in silico modelling and toxicity evaluation
( MDPI , 2021 , Article)Norfloxacin (NOR), widely employed as an anti-bacterial drug, has poor oral bioavailability. Nano based drug delivery systems are widely used to overcome the existing oral bioavailability challenges. Lipid–Polymer Hybrid ... -
Impact of nanosizing on the formation and characteristics of polymethacrylate films: micro- versus nano-suspensions
( Taylor and Francis Ltd. , 2021 , Article)Aqueous-based film coating suspensions are associated with reliance on alkalinising reagents and poor film formation. The impact of particle size in this process and resultant film properties remains unclear. This study ... -
Fabrication, characterization and optimization of nanostructured lipid carrier formulations using Beclomethasone dipropionate for pulmonary drug delivery via medical nebulizers
( Elsevier , 2021 , Article)Aerosolization is a non-invasive approach in drug delivery for localized and systemic effect. Nanostructured lipid carriers (NLCs) are new generation versatile carriers, which offer protection from degradation and enhance ... -
Introduction to nanotechnology
( Elsevier , 2019 , Book chapter)Nanotechnology describes the science and technology related to the control and manipulation of matter and devices on a scale less than 100 nm and involves fields such as applied physics, materials science, chemistry, ... -
Galactosylated iron oxide nanoparticles for enhancing oral bioavailability of ceftriaxone
( Taylor and Francis Ltd. , 2021 , Article)The current study focuses on the development, characterization, biocompatibility investigation and oral bioavailability evaluation of ceftriaxone (CFT)-loaded lactobionic acid (LBA)-functionalized iron oxide magnetic ... -
Liposomes for pulmonary drug delivery: The role of formulation and inhalation device design
( Bentham Science Publishers B.V. , 2017 , Article Review)Liposomes are established drug carriers for inhalation owing to their safety and ability to provide controlled drug release in the lung. These carriers can entrap a wide range of therapeutic molecules for delivery in large ... -
Guiding Factors and Surface Modification Strategies for Biomaterials in Pharmaceutical Product Development
( Elsevier , 2019 , Book chapter)With the technological advent in the field of drug delivery and medicines, biomaterials become important owing to their properties such as biocompatibility, functionality, and bioactive and bioinert nature. However, the ... -
PEGylated graphene oxide for tumor-targeted delivery of paclitaxel
( Future Medicine Ltd. , 2015 , Article)Aim: The graphene oxide (GO) sheet has been considered one of the most promising carbon derivatives in the field of material science for the past few years and has shown excellent tumor-targeting ability, biocompatibility ... -
Piroxicam loaded polymer hybrid microspheres based tablets with modified release kinetics: Development, characterization and in vivo evaluation
( Pakistan Journal of Pharmaceutical Sciences , 2021 , Article)Piroxicam (PC) is a non-steroidal anti-inflammatory drug characterized by poor aqueous solubility and reported to cause and impart crucial GIT irritation, bleeding, peptic and duodenal ulcer. Engineering of PC ... -
Recent advancements in stimuli responsive drug delivery platforms for active and passive cancer targeting
( MDPI AG , 2021 , Article Review)The tumor-specific targeting of chemotherapeutic agents for specific necrosis of cancer cells without affecting the normal cells poses a great challenge for researchers and scientists. Though extensive research has been ... -
Proliposome Powders for the Generation of Liposomes: the Influence of Carbohydrate Carrier and Separation Conditions on Crystallinity and Entrapment of a Model Antiasthma Steroid
( Springer New York LLC , 2018 , Article)Formulation effects on the entrapment of beclometasone dipropionate (BDP) in liposomes generated by hydration of proliposomes were studied, using the high-density dispersion medium deuterium oxide in comparison to deionized ... -
Fabrication of hesperidin hybrid lecithin-folic acid silver nanoparticles and its evaluation as anti-arthritis formulation in autoimmune arthritic rat model.
( Elsevier , 2023 , Article)Rheumatoid arthritis (RA) is an immune-mediated inflammatory disease that results in synovitis, cartilage destruction and loss of joint function. The frequent and long-term administration of anti-rheumatic drugs often leads ... -
Cyclodextrin diethyldithiocarbamate copper ii inclusion complexes: A promising chemotherapeutic delivery system against chemoresistant triple negative breast cancer cell lines
( MDPI AG , 2021 , Article)Diethyldithiocarbamate Copper II (DDC-Cu) has shown potent anticancer activity against a wide range of cancer cells, but further investigations are hindered by its practical insolubility in water. In this study, inclusion ... -
Amlexanox-loaded nanoliposomes showing enhanced anti-inflammatory activity in cultured macrophages: A potential formulation for treatment of oral aphthous stomatitis
( Elsevier , 2023 , Article)Oral aphthous stomatitis is a common disorder treated with the immunomodulatory drug Amlexanox (AMX), that was administered as a mucoadhesive paste (Aphthasol®). This product was discontinued by FDA in 2014 due to the ... -
A comprehensive production method of self-cryoprotected nano-liposome powders
( Elsevier , 2015 , Article)This study provided a convenient approach for large scale production of hydrogenated soya phosphatidylcholine nano-liposome powders using beclometasone dipropionate as a model drug and sucrose as proliposome carrier. ... -
The impact of COVID-19 on antimicrobial stewardship programme implementation in hospitals – an exploration informed by the Consolidated Framework for Implementation Research
( Elsevier , 2022 , Article)Introduction and objectivesThe disruption of antimicrobial stewardship programmes (ASPs) caused by coronavirus disease 2019 (COVID-19) has been recognized but not explored in depth. This study used a theoretical, qualitative ... -
Interprofessional Interventions Involving Pharmacists and Targeting the Medicines Management Process Provided to Older People Residing in Nursing Homes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
( Springer , 2022 , Article)Background: Nursing home residents are often prescribed multiple medications, which increases their susceptibility to drug-related problems. The medicines management process involves multiple stages, for example, assessing, ... -
A scoping review of theories used to investigate clinician adherence to clinical practice guidelines
( Springer , 2022 , Article Review)Background: Routine utilization of evidence-based clinical practice guidelines (CPGs) is an effective strategy to optimize patient care and reduce practice variation. Healthcare professionals’ failure to adhere to CPGs ... -
Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study
( Elsevier , 2022 , Article)BackgroundThe study aimed to assess burnout, resilience, and levels of depression, anxiety, stress and fear among community pharmacists during the pandemic, and examine if fear of COVID-19 is associated with these outcomes ...
