College of Pharmacy: Recent submissions
Now showing items 941-960 of 1315
-
A Facile and Novel Approach to Manufacture Paclitaxel-Loaded Proliposome Tablet Formulations of Micro or Nano Vesicles for Nebulization
( Springer , 2020 , Article)© 2020, The Author(s). Purpose: The aim of this study was to develop novel paclitaxel-loaded proliposome tablet formulations for pulmonary drug delivery. Method: Proliposome powder formulations (i.e. F1 – F27) were prepared ... -
Paclitaxel-loaded micro or nano transfersome formulation into novel tablets for pulmonary drug delivery via nebulization
( Elsevier , 2020 , Article)A simplistic approach was adopted to manufacture novel paclitaxel (PTX) loaded protransfersome tablet formulations for pulmonary drug delivery. The large surface area offered by the pulmonary system acts as a desirable ... -
Proliposome powder or tablets for generating inhalable liposomes using a medical nebulizer
( Springer , 2021 , Article)© 2020, The Author(s). Purpose: The aim of this study was to develop and compare proliposome powder and proliposome tablet formulations for drug delivery from a Pari-LC Sprint nebulizer. Methods: Proliposome powders were ... -
Development, characterization and stability evaluation of ciprofloxacin-loaded parenteral nutrition nanoemulsions
( Taylor and Francis , 2020 , Article)© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. In this study, two licensed total parenteral nanoemulsion formulations (Clinoleic® and Intralipid®) were loaded with ciprofloxacin (CP). The physicochemical ... -
Efficient design to fabricate smart Lumefantrine nanocrystals using DENA® particle engineering technology: Characterisation, in vitro and in vivo antimalarial evaluation and assessment of acute and sub-acute toxicity
( Elsevier , 2020 , Article)Nanocrystalization technologies have a great potential to substantially increase solubility as well as alleviate the erratic bioavailability behaviour of a range of poorly water soluble drugs. The aim of the current study ... -
Carbon nanotubes drug delivery system for cancer treatment
( Academic Press , 2020 , Book chapter)There has been a predominant interest in using nanotechnology for drug delivery applications, especially for cite-specific targeting. Recently, interest in the potential of carbon nanotubes (CNT) to deliver bio-molecules ... -
Characterization of cochleate nanoparticles for delivery of the anti-asthma drug beclomethasone dipropionate
( Academic Press , 2020 , Book chapter)Cochleates are an exciting new class of nanocarriers derived from multilamellar liposomes. They have a “cigerette like” structures in which the phospholipid bilayers are joined together by calcium ion bridges making them ... -
Taxane anticancer formulations: challenges and achievements
( Academic Press , 2020 , Book chapter)Taxanes represent a prominent anticancer family. Paclitaxel and docetaxel are the most well-known taxanes owing to their activity against many types of cancers. The poor solubility of taxanes in water is a major obstacle ... -
Advances in nasal drug delivery systems
( Academic Press , 2020 , Book chapter)Nasal drug delivery has been around for centuries and employed both leisure and recreations and also for the treatment of various conditions such as migraine, decongestion, sinusitis, rhinitis, and in emergency. The route ... -
Use of Normalization Process Theory to explore key stakeholders’ perceptions of the facilitators and barriers to implementing electronic systems for medicines management in hospital settings
( Research in Social and Administrative Pharmacy , 2021 , Article)BackgroundLimited data exist on the facilitators and barriers to implementing electronic systems for medicines management in hospitals. Whilst numerous studies advocate system use in improved patient safety and efficiency ... -
Endoplasmic reticulum stress and oxidative stress drive endothelial dysfunction induced by high selenium
( Wiley , 2020 , Article)Selenium is an essential trace element important for human health. A balanced intake is, however, crucial to maximize the health benefits of selenium. At physiological concentrations, selenium mediates antioxidant, ... -
Implementation models: applicability across research, implementation, culture and context
( University of Adelaide, Joanna Briggs Institute , 2020 , Article)The Joanna Briggs Institute (JBI) Model for Evidencebased Healthcare is a whole-of-health model that brings together healthcare needs, research generation, synthesis, transfer and implementation while accounting ... -
Pharmacists providing prescribing advice and education to healthcare professionals in community, primary care and outpatient settings (Protocol)
( Wiley , 2020 , Article)Objectives This is a protocol for a Cochrane Review (intervention). The objectives are as follows: Main objective To assess the eHect of pharmacists’ prescribing advice, compared to usual care or other forms of ... -
A Review of Clinical Outcomes Associated with Two Meropenem Dosing Strategies
( Springer International Publishing , 2017 , Article Review)Meropenem is a carbapenem antibiotic that exhibits time-dependent bactericidal activity, traditionally dosed intravenously at 1�g every 8�h. In order to maximize its pharmacodynamic activity and reduce costs, an alternative ... -
Can source triangulation be used to overcome limitations of self-assessments? Assessing educational needs and professional competence of pharmacists practicing in qatar
( John Wiley and Sons Inc. , 2017 , Article)Introduction: Continuing professional development activities should be designed to meet the identified personal goals of the learner. This article aims to explore the self-perceived competency levels and the professional ... -
Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
( Springer International Publishing , 2017 , Article Review)Background Genetic polymorphisms are known to influence outcomes with phenytoin yet effects in the Middle East and North Africa region are poorly understood. Objectives The objective of this systematic review was to ... -
A Systematic Review of Antimicrobial Stewardship Interventions in the Emergency Department
( SAGE Publications Inc. , 2017 , Article Review)Background/Objective: To improve antimicrobial utilization, development and implementation of antimicrobial stewardship programs in the emergency department (ED) has been recommended. The primary objective of this review ... -
Synthesizing and Appraising the Quality of the Evidence on Factors Associated with Medication Adherence in Diabetes: A Systematic Review of Systematic Reviews
( Elsevier Inc. , 2017 , Article)Background Nonadherence to medications is a common phenomenon in patients with diabetes. Several studies and systematic reviews have investigated the barriers to medication adherence in diabetes. However, no study has ... -
Advancing the Visibility, Impact, and Quality Metrics of Value in Health Regional Issues
( Elsevier Inc. , 2017 , Article)[No abstract available] -
Medical comorbidities in patients with serious mental illness: A retrospective study of mental health patients attending an outpatient clinic in Qatar
( Dove Medical Press Ltd. , 2017 , Article)Background: The life span of individuals with serious mental illness (SMI) is shorter compared to the general population. This excess mortality is mainly due to physical illness. The aim of the study was to investigate the ...
