Chronic Wound Healing Models
الملخص
In this paper, we review and analyze the commonly available wound healing models reported in the literature and discuss their advantages and issues, considering their relevance and translational potential to humans. Our analysis includes different in vitro and in silico as well as in vivo models and experimental techniques. We further explore the new technologies in the study of wound healing to provide an all encompassing review of the most efficient ways to proceed with wound healing experiments. We revealed that there is not one model of wound healing that is superior and can give translatable results to human research. Rather, there are many different models that have specific uses for studying certain processes or stages of wound healing. Our analysis suggests that when performing an experiment to assess stages of wound healing or different therapies to enhance healing, one must consider not only the species that will be used but also the type of model and how this can best replicate the physiology or pathophysiology in humans.
معرّف المصادر الموحد
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85154529968&origin=inwardالمجموعات
- أبحاث الطب [1382 items ]
وثائق ذات صلة
عرض الوثائق المتصلة بواسطة: العنوان، المؤلف، المنشئ والموضوع.
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The Therapeutic Wound Healing Bioactivities of Various Medicinal Plants
Albahri, Ghosoon; Badran, Adnan; Hijazi, Akram; Daou, Anis; Baydoun, Elias; Nasser, Mohamad; Merah, Othmane... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)The skin serves as the body’s first line of defense, guarding against mechanical, chemical, and thermal damage to the interior organs. It includes a highly developed immune response that serves as a barrier against pathogenic ... -
Evaluation of the Wound Healing Potential of Hypericum triquetrifolium Turra: An Experimental Animal Study and Histopathological Examination
El-Elimat, Tamam; El-Qaderi, Haya S.; Hananeh, Wael M.; Abu AlSamen, Mahmoud M.; Al Sharie, Ahmed H.; Alshehabat, Musa A.; Al-Gharaibeh, Mohammad; Alali, Feras Q.... more authors ... less authors (2023 , Article)The wound healing potential of the aerial parts of Hypericum triquetrifolium Turra (Hypericaceae) was evaluated using an in vivo excision wound model in rats. Adult male Sprague Dawley rats were randomly assigned into seven ... -
The effect of aging on the bone healing properties of blood plasma
Al-Hamed F.S.; Rodan R.; Ramirez-Garcialuna J.L.; Elkashty O.; Al-Shahrani N.; Tran S.D.; Lordkipanidz� M.; Kaartinen M.; Badran Z.; Tamimi F.... more authors ... less authors ( Elsevier Ltd , 2021 , Article)Objectives: Age-related changes in blood composition have been found to affect overall health. Thus, this study aimed to understand the effect of these changes on bone healing by assessing how plasma derived from young and ...