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المؤلفChristopher, Christina Malini
المؤلفBhuvan, K. C.
المؤلفBlebil, Ali
المؤلفAlex, Deepa
المؤلفIbrahim, Mohamed Izham Mohamed
المؤلفIsmail, Norhasimah
المؤلفAlrasheedy, Alian A.
تاريخ الإتاحة2023-07-27T06:40:01Z
تاريخ النشر2021-11-18
اسم المنشورHealthcare (Switzerland)
المعرّفhttp://dx.doi.org/10.3390/healthcare9111577
الاقتباسChristopher, C. M., Kc, B., Blebil, A., Alex, D., Ibrahim, M. I. M., Ismail, N., & Alrasheedy, A. A. (2021, November). Clinical and humanistic outcomes of community pharmacy-based healthcare interventions regarding medication use in older adults: a systematic review and meta-analysis. In Healthcare (Vol. 9, No. 11, p. 1577). MDPI.
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85119851096&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/46358
الملخصThis review and meta‐analysis aimed to determine the clinical and humanistic outcomes of community pharmacy‐based interventions on medication‐related problems of older adults at the primary care level. We identified randomized controlled trials (RCTs) examining the impact of various community pharmacy‐based interventions from five electronic databases (namely, MEDLINE (Ovid), EMBASE (Ovid), CINAHL, APA PSYInfo, and Scopus) from January 2010 to December 2020. Consequently, we assessed these interventions’ clinical and humanistic outcomes on older adults and compared them with non‐intervention. We included 13 RCTs in the current review and completed a meta‐analysis with six of them. The included studies had a total of 6173 older adults. Quantitative analysis showed that patient education was significantly associated with an increase in the discontinuation of sedative–hypnotics use (risk ratio 1.28; 95% CI (1.20, 1.36) I2 = 0%, p < 0.00001). Moreover, the qualitative analysis showed that medication reviews and education with follow‐ups could improve various clinical outcomes, including reducing adverse drug events, reducing uncontrolled health outcomes, and improving appropriate medication use among the elderly population. However, medication review could not significantly reduce the number of older adults who fall (risk ratio 1.25; 95% CI (0.78, 1.99) I2 = 0%, p = 0.36) and require hospitalization (risk ratio 0.72; 95% CI (0.47, 1.12) I2 = 45%, p = 0.15). This study showed that community pharmacy‐based interventions could help discontinue inappropriate prescription medications among older adults and could improve several clinical and humanistic outcomes. However, more effective community pharmacy‐based interventions should be implemented, and more research is needed to provide further evidence for clinical and humanistic outcomes of such interventions on older adults.
اللغةen
الناشرMultidisciplinary Digital Publishing Institute (MDPI)
الموضوعCommunity pharmacy
Intervention
Older adults
Outcomes
Systematic review
العنوانClinical and humanistic outcomes of community pharmacy‐based healthcare interventions regarding medication use in older adults: A systematic review and meta‐analysis
النوعArticle
رقم العدد11
رقم المجلد9
ESSN2227-9032
dc.accessType Open Access


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