College of Health Sciences: المرسلات الحديثة
السجلات المعروضة 1521 -- 1540 من 1696
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Qatar Biobank and Qatar Genome Programs Road Map
( OMICS International , 2015 , Article)Qatar Biobank “QBB” is a large-scale, long term medical research initiative for the population of Qatar, which will serve as a platform and driver of biomedical research to achieve benefits for Qatar’s communities. Following ... -
Novel Quinuclidinone Derivatives Induced Apoptosis in Human Breast Cancer via Targeting P53
( Elsevier , 2017 , Article)Small molecules that can target human cancers have been highly sought to increase the anticancer efficacy, the present work describes the design and synthesis of novel series of five quinuclidinone derivatives (2a-2e). ... -
Antitumor Activities of the Novel Isosteviol Derivative 10C Against Liver Cancer
( International Institute of Anticancer Research , 2017 , Article)Background/Aim. Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the fifth most common primary malignancy with worldwide increasing incidence. The current study aims to investigate the anticancer ... -
Pharmacotherapy of Persons with Dementia in Long-Term Care in Australia: A Descriptive Audit of Central Nervous System Medications
( Bentham Science Publishers , 2017 , Article)BACKGROUND: Neuropsychiatric symptoms of dementia are often treated through the prescription of one or more psychotropic medications. However, limited efficacy and potential harmful side-effects has resulted in efforts ... -
Synthesis, characterization, and antimicrobial properties of novel double layer nanocomposite electrospun fibers for wound dressing applications
( Dove Press , 2017 , Article)Herein, novel hybrid nanomaterials were developed for wound dressing applications with antimicrobial properties. Electrospinning was used to fabricate a double layer nanocomposite nanofibrous mat consisting of an upper ... -
Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer’s therapy
( Elsevier , 2017 , Article)Abstract We designed a delivery system to obtain an efficient and optimal nose-to-brain transport of BACE1 siRNA, potentially useful in the treatment of Alzheimer's disease. We selected a cell-penetrating peptide, the short ... -
Initial psychometric testing and validation of the Patient Participation in Pressure Injury Prevention scale
( Wiley , 2017 , Article)AIMS: The aim of this study was to develop the Patient Participation in Pressure Injury Prevention (PPPIP) scale and undertake initial testing of some of its psychometric properties. BACKGROUND: Clinical practice ... -
Allergenicity of roasted peanuts treated with a non-human digestive protease
( Elsevier Ltd , 2015 , Article)Peanut allergy is a severe and lifelong type of food allergy triggered by allergenic proteins and peptides in peanuts. This study investigated the effects of ultrasound-assisted alcalase treatment on the concentrations of ... -
Physico-chemical characterization of biochars from solid municipal waste for use in soil amendment
( Elsevier B.V. , 2016 , Article)The fast economic and demographic growth lead to generation of large amounts of solid wastes placing Qatar on top of most nations with a per capita solid waste generation of nearly 2.5 milliontons/year of which 60% is ... -
Bioavailability and hypolipidemic effects of peanut skin polyphenols
( Mary Ann Liebert, Inc. , 2015 , Article)Peanut skin is a rich source of polyphenols, such as proanthocyanidins. Peanut skin proanthocyanidins mainly consist of a subgroup called procyanidins. Peanut-based procyanidins contain oligomers of both type A and type ... -
Assessment of morphological changes due to oxidative stress: leukodepleted packed red blood cells stored in SAGM
( Canadian Society of Transfusion Medicine , 2016 , Conference Paper)Background: In blood bank, the storage procedures of packed red blood cell (pRBC) require some conditions to ensure the maximum storage time for a safe blood supply. pRBC can be stored up to 42 days in 2-6⁰C, as long as ... -
Frequency of Clinically Important RH and Kell Blood Group Antigens Among Blood Donors in Qatar
( HBKU Press , 2016 , Conference Paper)Background Very limited information is available about the prevalence of blood groups among Qatari population and residents. The information about frequencies of different blood group antigens is important to manage, ... -
Tea flavanols block advanced glycation of lens crystallins induced by dehydroascorbic acid
( American Chemical Society , 2015 , Article)Growing evidence has shown that ascorbic acid (ASA) can contribute to protein glycation and the formation of advanced glycation end products (AGEs), especially in the lens. The mechanism by which ascorbic acid can cause ... -
Cardiac autonomic regulation as a predictor for childhood obesity intervention success.
( Nature Publishing Group , 2017 , Article)Childhood obesity is a major public health concern; behavioural interventions induce weight reduction in some, but success is variable. Heart rate variability (HRV) has been associated with impulse control and extent of ... -
Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity
( Elsevier , 2017 , Article)Abstract Epigallocatechin 3-gallate (EGCG) from green tea may reduce plasma glucose and alleviate complications of diabetes by attenuating advanced glycation end products (AGEs) formation. We hypothesized that EGCG would ... -
In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol
( Elsevier , 2016 , Article)Abstract Hyperglycemic stress activates polyol pathway and aldose reductase (AR) key enzyme responsible for generating secondary complications during diabetes. In this study the therapeutic potential of phloretin, ... -
Bioactive compounds isolated from apple, tea, and ginger protect against dicarbonyl induced stress in cultured human retinal epithelial cells
( Elsevier , 2016 , Article)Abstract BackgroundMethylglyoxal (MGO) is known to be a major precursor of advanced glycation end products (AGEs) which are linked to diabetes and its related complications. Naturally occurring bioactive compounds could ... -
Effect of biochars produced from solid organic municipal waste on soil quality parameters
( Elsevier , 2017 , Article)Abstract New value-added uses for solid municipal waste are needed for environmental and economic sustainability. Fortunately, value-added biochars can be produced from mixed solid waste, thereby addressing solid waste ... -
Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa
( Taylor & Francis , 2017 , Article)Over the past two decades, studies have documented the wide-range anti-cancer effects of Nigella sativa, known as black seed or black cumin. Thymoquinone (TQ), its major active ingredient, has also been extensively studied ... -
Health Informatics Tools to Improve Utilization of Laboratory Tests
( Oxford University Press , 2017 , Article)Herein, we discuss improper test utilization practices and their implications on delivery of health care, as well as providing a brief explanation of the means to reduce such practices by improvement of personnel factors, ...