College of Health Sciences: المرسلات الحديثة

السجلات المعروضة 421 -- 440 من 1696

    • Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population 

      Elkamel, Sarra; Marques, Sofia L.; Alvarez, Luis; Gomes, Veronica; Boussetta, Sami; ... more authors ( Nature Research , 2021 , Article)
      To obtain refreshed insights into the paternal lineages of Tunisian populations, Y-chromosome diversity was assessed in two populations belonging to an Arab genealogical lineage, Kairouan and Wesletia, as well as in four ...

    • Characterization of critical health promotion: a scoping review protocol. 

      Fincham, Susanne; O'Hara, Lily; Cole, Rachel; Taylor, Jane ( Lippincott, Williams & Wilkins , 2023 , Other)
      This scoping review will explore how critical health promotion is characterized in the health promotion literature. Critical health promotion has emerged as a social justice approach to health promotion to address the ...

    • Biological applications of imiquimod analogues: An update (Review) 

      Obeid, Joelle; Shaito, Abdullah; Hajj, Hiba El; Deleuze-Masquefa, Carine; Bonnet, Pierre Antoine; ... more authors ( Spandidos Publications , 2023 , Article Review)
      The last decade witnessed intensive efforts in drug discovery and the emergence of thousands of molecules with potential for use as therapeutic targets. However, only a few hundred of these molecules reached the stage of ...

    • 3D hydrogel/ bioactive glass scaffolds in bone tissue engineering: Status and future opportunities 

      Abdullah, Aldhaher; Shahabipour, Fahimeh; Shaito, Abdullah; Al-Assaf, Saphwan; Elnour, Ahmed A.M.; ... more authors ( Elsevier , 2023 , Article Review)
      Repairing significant bone defects remains a critical challenge, raising the clinical demand to design novel bone biomaterials that incorporate osteogenic and angiogenic properties to support the regeneration of vascularized ...

    • Biochemical and cellular basis of oxidative stress: Implications for disease onset 

      Aramouni, Karl; Assaf, Roland; Shaito, Abdullah; Fardoun, Manal; Al-Asmakh, Maha; ... more authors ( Wiley , 2023 , Article Review)
      Cellular oxidation–reduction (redox) systems, which encompass pro- and antioxidant molecules, are integral components of a plethora of essential cellular processes. Any dysregulation of these systems can cause molecular ...

    • Repositioning of the global epicentre of non-optimal cholesterol 

      Taddei, Cristina; Zhou, Bin; Bixby, Honor; Carrillo-Larco, Rodrigo M.; Danaei, Goodarz; ... more authors ( Nature Research , 2020 , Article)
      High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using ...

    • Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants 

      Bin, Zhou; Bentham, James; Di Cesare, Mariachiara; Bixby, Honor; Danaei, Goodarz; ... more authors ( Elsevier , 2017 , Article)
      Background Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, ...

    • Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction 

      Fardoun, Manal M.; Issa, Khodr; Maaliki, Dina; Nasser, Suzanne A.; Baydoun, Elias; ... more authors ( Elsevier , 2020 , Article)
      Cutaneous cold-induced vasoconstriction is a normal physiological reaction mediated by alpha 2C-adrenergic receptors (α2C-ARs) expressed in vascular smooth muscle cells (VSMCs). When this reaction is exaggerated, Raynaud's ...

    • Measuring influenza hemagglutinin (HA) stem-specific antibody-dependent cellular cytotoxicity (ADCC) in human sera using novel stabilized stem nanoparticle probes 

      Smatti, Maria K.; Nasrallah, Gheyath K.; Al Thani, Asmaa A.; Yassine, Hadi M. ( Elsevier , 2020 , Article)
      Background: Generating vaccine that confers a complete protection is a major goal in designing a universal influenza vaccine. Currently, there is a considerable interest in the broadly neutralizing antibodies (bnAb) targeting ...

    • The hypertensive potential of estrogen: An untold story 

      Fardoun, Manal; Dehaini, Hassan; Shaito, Abdallah; Mesmar, Joelle; El-Yazbi, Ahmed; ... more authors ( Elsevier , 2020 , Article Review)
      Cardiovascular disease (CVD) is the major cause of morbidity and mortality worldwide. The implication of estrogen in this disease has been extensively studied. While the vast majority of published research argue for a ...

    • The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals 

      Singh, Parul; Rawat, Arun; Alwakeel, Mariam; Sharif, Elham; Al Khodor, Souhaila ( Nature Research , 2020 , Article)
      Vitamin D deficiency affects approximately 80% of individuals in some countries and has been linked with gut dysbiosis and inflammation. While the benefits of vitamin D supplementation on the gut microbiota have been studied ...

    • A population study of clinically actionable genetic variation affecting drug response from the Middle East 

      Jithesh, Puthen Veettil; Abuhaliqa, Mohammed; Syed, Najeeb; Ahmed, Ikhlak; El Anbari, Mohammed; ... more authors ( Nature Research , 2022 , Article)
      Clinical implementation of pharmacogenomics will help in personalizing drug prescriptions and alleviate the personal and financial burden due to inefficacy and adverse reactions to drugs. However, such implementation is ...

    • Immunomodulatory Properties of Human Breast Milk: MicroRNA Contents and Potential Epigenetic Effects 

      Hatmal, Ma’Mon M.; Al-Hatamleh, Mohammad A.I.; Olaimat, Amin N.; Alshaer, Walhan; Hasan, Hanan; ... more authors ( MDPI , 2022 , Article)
      Infants who are exclusively breastfed in the first six months of age receive adequate nutrients, achieving optimal immune protection and growth. In addition to the known nutritional components of human breast milk (HBM), ...

    • Mass Spectrometry, Structural Analysis, and Anti-Inflammatory Properties of Photo-Cross-Linked Human Albumin Hydrogels 

      Sharifi, Shahriar; Saei, Amir Ata; Gharibi, Hassan; Mahmoud, Nouf N.; Harkins, Shannon; ... more authors ( American Chemical Society , 2022 , Article)
      Albumin-based hydrogels offer unique benefits such as biodegradability and high binding affinity to various biomolecules, which make them suitable candidates for biomedical applications. Here, we report a non-immunogenic ...

    • Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis, first update 

      Imad M., Tleyjeh; Kashour, Zakariya; Riaz, Muhammad; Hassett, Leslie; Veiga, Viviane C.; ... more authors ( Elsevier , 2021 , Article)
      ObjectivesCytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our objective was to update the data in a living ...

    • Characterizing epidemiology of prediabetes, diabetes, and hypertension in Qataris: A cross-sectional study 

      Al-Thani, Mohammed H.; Al-Mutawa, Kholood A.; Alyafei, Salah A.; Ijaz, Muhammad A.; Khalifa, Shamseldin A.H.; ... more authors ( Public Library of Science , 2021 , Article)
      Objectives To characterize the epidemiologic profiles of prediabetes mellitus (preDM), diabetes mellitus (DM), and hypertension (HTN) in Qataris using the nationally representative 2012 Qatar STEPwise Survey. Methods A ...

    • A systematic review of interventions to promote physical activity in six Gulf countries 

      Nash, Elizabeth A.; Critchley, Julia A.; Pearson, Fiona; Awad, Susanne F.; Abu-Raddad, Laith J.; ... more authors ( Public Library of Science , 2021 , Article)
      Physical activity (PA) levels are low in Gulf Cooperation Council countries (GCC; Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, United Arab Emirates). We carried out a systematic review (PROSPERO registration number 131817) ...

    • Estimates of global SARS-CoV-2 infection exposure, infection morbidity, and infection mortality rates in 2020 

      Houssein H., Ayoub; Mumtaz, Ghina R.; Seedat, Shaheen; Makhoul, Monia; Chemaitelly, Hiam; ... more authors ( Elsevier , 2021 , Article)
      We aimed to estimate, albeit crudely and provisionally, national, regional, and global proportions of respective populations that have been infected with SARS-CoV-2 in the first year after the introduction of this virus ...

    • Effectiveness of pharmacological and psychological interventions for treating post-traumatic stress disorder in adults with childhood abuse: Protocol for a systematic review and network meta-analysis 

      Alhussaini, Nour Waleed; Riaz, Muhammad ( BMJ Publishing Group , 2021 , Article)
      Introduction Post-traumatic stress disorder (PTSD) is a debilitating mental disorder that develops after being exposed to a traumatic event. PTSD is common among adults who have experienced physical/sexual childhood abuse. ...

    • Waning effectiveness of COVID-19 vaccines 

      Hiam, Chemaitelly; Abu-Raddad, Laith J ( Elsevier , 2022 , Article)
      In The Lancet, Peter Nordström and colleagues1 report the effectiveness of several COVID-19 vaccines and different vaccine schedules against any documented SARS-CoV-2 infection and against severe COVID-19, for up to 9 ...