College of Health Sciences: Recent submissions
Now showing items 401-420 of 1726
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The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity
( Springer , 2023 , Article Review)Targeted therapy, such as tyrosine kinase inhibitors (TKIs), has been approved to manage various cancer types. However, TKI-induced cardiotoxicity is a limiting factor for their use. This issue has raised the need for ... -
Epac in vascular smooth muscle cells
( MDPI , 2020 , Article Review)Vascular smooth muscle cells (VSMCs) are major components of blood vessels. They regulate physiological functions, such as vascular tone and blood flow. Under pathological conditions, VSMCs undergo a remodeling process ... -
The mitochondria: A target of polyphenols in the treatment of diabetic cardiomyopathy
( MDPI , 2020 , Article)Diabetic cardiomyopathy (DCM) is a constellation of symptoms consisting of ventricular dysfunction and cardiomyocyte disarray in the presence of diabetes. The exact cause of this type of cardiomyopathy is still unknown; ... -
Traumatic brain injury: Oxidative stress and novel anti-oxidants such as mitoquinone and edaravone
( MDPI , 2020 , Article Review)Traumatic brain injury (TBI) is a major health concern worldwide and is classified based on severity into mild, moderate, and severe. The mechanical injury in TBI leads to a metabolic and ionic imbalance, which eventually ... -
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
( Elsevier , 2016 , Article)Background: Cardiovascular disease (CVD) remains the leading cause of global death, with atherosclerosis being a major contributor to this mortality. Several mechanisms are implicated in the pathogenesis of this disease. ... -
Inflammatory basis of atherosclerosis: Modulation by sex hormones
( Bentham Science Publishers , 2021 , Article Review)Atherosclerosis-related cardiovascular diseases (CVDs) are the leading cause of death globally. Several lines of evidence are supportive of the contributory role of vascular inflammation in atherosclerosis. Di-verse immune ... -
Drug repurposing in neurodegenerative and cardiovascular diseases
( Bentham Science Publishers , 2021 , Article)No Abstract -
Drug repurposing in cancer: Now and beyond
(2021 , Article)No Abdtract -
Repurposing cilostazol for raynaud's phenomenon
( Bentham Science Publishers , 2021 , Article Review)Raynaud's Phenomenon (RP) results from exaggerated cold-induced vasoconstriction. RP patients suffer from vasospastic attacks and compromised digital blood perfusion leading to a triple color change at the level the fingers. ... -
Is age of menarche among school girls related to academic performance
( De Gruyter , 2019 , Article)There is strong evidence that the mean age of menarche has declined over the last few decades in developed and developing countries. This is of a major concern because of its enormous public health implications. This study ... -
Diabetes Self-Management Education and Support: Referral and Attendance at a Patient-Centered Medical Home
( SAGE Publications Inc. , 2020 , Article)Background: Although evidence shows that diabetes self-management education and support (DSMES) is an effective tool to help individuals with type 2 diabetes (T2DM) improve their health outcomes, there remains a large ... -
The strength of association between psychological factors and clinical outcome in tendinopathy: A systematic review
( Public Library of Science , 2020 , Article Review)Objective Tendinopathy is often a disabling, and persistent musculoskeletal disorder. Psychological factors appear to play a role in the perpetuation of symptoms and influence recovery in musculoskeletal pain. To date, the ... -
Posterior shoulder tightness; an intersession reliability study of 3 clinical tests
( BioMed Central Ltd , 2020 , Article)Background Although posterior shoulder tightness (PST) has been associated with shoulder pathology and altered glenohumeral joint kinematics, uncertainty remains regarding its cause and definition. To understand the ... -
A cross-sectional study on the impact of the COVID-19 pandemic on psychological outcomes: Multiple indicators and multiple causes modeling
( Public Library of Science , 2022 , Article)Although the psychological impact of coronavirus disease 2019 (COVID-19) has been evaluated in the literature, further research is needed, particularly on post-traumatic stress disorder (PTSD) and psychological outcomes, ... -
Characterization of neurobehavioral pattern in a zebrafish 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced model: A 96-hour behavioral study
( Public Library of Science , 2022 , Article)Parkinson’s disease (PD) is the most common brain motor disorder, characterized by a substantial loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Motor impairments, such as dyskinesia, bradykinesia, ... -
Assessment of Nutrients Associated With the Risk of Osteoporosis in Postmenopausal Women: A Case-Control Study
( Enviro Research Publishers , 2022 , Article)Osteoporosis is a chronic bone disease characterized by the loss in bone density and modification in bone structure. These changes will increase bone fragility and the risk of fracture particularly among postmenopausal ... -
The Spectrum of Genetic Variants Associated with the Development of Monogenic Obesity in Qatar
( S. Karger AG , 2022 , Article)Introduction: Monogenic obesity (MO) is a rare genetic disease characterized by severe early-onset obesity in affected individuals. Previous genetic studies revealed 8 definitive genes for monogenic non-syndromic obesity; ... -
Seven novel glucose-6-phosphate dehydrogenase (G6PD) deficiency variants identified in the Qatari population
( BioMed Central Ltd , 2021 , Article)Background: Glucose-6-phosphate dehydrogenase deficiency (G6PDD) is the most common red cell enzymopathy in the world. In Qatar, the incidence of G6PDD is estimated at around 5%; however, no study has investigated the ... -
Positioning the Scholarship of Teaching and Learning Firmly in the Center of Health Promotion Pedagogy
( SAGE Publications Inc. , 2022 , Article)Historically, the work of Scholarship of Teaching and Learning (SoTL) scholars has been grounded in multi-disciplinary connections to educational psychology and pedagogical research. SoTL research and commentary intends ... -
Impact of the COVID-19 lockdown on lifestyle behaviors and their association with personality among adults in Qatar: A cross-sectional study
( Public Library of Science , 2022 , Article)The coronavirus pandemic (COVID-19) resulted in lockdowns and social distancing measures enforced by governments around the world. This study aimed to identify changes in adherence to the Mediterranean diet (MD) and physical ...
