College of Health Sciences: Recent submissions
Now showing items 461-480 of 1726
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The hypertensive potential of estrogen: An untold story
( Elsevier , 2020 , Article Review)Cardiovascular disease (CVD) is the major cause of morbidity and mortality worldwide. The implication of estrogen in this disease has been extensively studied. While the vast majority of published research argue for a ... -
Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction
( Elsevier , 2020 , Article)Cutaneous cold-induced vasoconstriction is a normal physiological reaction mediated by alpha 2C-adrenergic receptors (α2C-ARs) expressed in vascular smooth muscle cells (VSMCs). When this reaction is exaggerated, Raynaud's ... -
The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals
( Nature Research , 2020 , Article)Vitamin D deficiency affects approximately 80% of individuals in some countries and has been linked with gut dysbiosis and inflammation. While the benefits of vitamin D supplementation on the gut microbiota have been studied ... -
A population study of clinically actionable genetic variation affecting drug response from the Middle East
( Nature Research , 2022 , Article)Clinical implementation of pharmacogenomics will help in personalizing drug prescriptions and alleviate the personal and financial burden due to inefficacy and adverse reactions to drugs. However, such implementation is ... -
Immunomodulatory Properties of Human Breast Milk: MicroRNA Contents and Potential Epigenetic Effects
( MDPI , 2022 , Article)Infants who are exclusively breastfed in the first six months of age receive adequate nutrients, achieving optimal immune protection and growth. In addition to the known nutritional components of human breast milk (HBM), ... -
Mass Spectrometry, Structural Analysis, and Anti-Inflammatory Properties of Photo-Cross-Linked Human Albumin Hydrogels
( American Chemical Society , 2022 , Article)Albumin-based hydrogels offer unique benefits such as biodegradability and high binding affinity to various biomolecules, which make them suitable candidates for biomedical applications. Here, we report a non-immunogenic ... -
Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis, first update
( Elsevier , 2021 , Article)ObjectivesCytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our objective was to update the data in a living ... -
Characterizing epidemiology of prediabetes, diabetes, and hypertension in Qataris: A cross-sectional study
( Public Library of Science , 2021 , Article)Objectives To characterize the epidemiologic profiles of prediabetes mellitus (preDM), diabetes mellitus (DM), and hypertension (HTN) in Qataris using the nationally representative 2012 Qatar STEPwise Survey. Methods A ... -
A systematic review of interventions to promote physical activity in six Gulf countries
( Public Library of Science , 2021 , Article)Physical activity (PA) levels are low in Gulf Cooperation Council countries (GCC; Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, United Arab Emirates). We carried out a systematic review (PROSPERO registration number 131817) ... -
Estimates of global SARS-CoV-2 infection exposure, infection morbidity, and infection mortality rates in 2020
( Elsevier , 2021 , Article)We aimed to estimate, albeit crudely and provisionally, national, regional, and global proportions of respective populations that have been infected with SARS-CoV-2 in the first year after the introduction of this virus ... -
Effectiveness of pharmacological and psychological interventions for treating post-traumatic stress disorder in adults with childhood abuse: Protocol for a systematic review and network meta-analysis
( BMJ Publishing Group , 2021 , Article)Introduction Post-traumatic stress disorder (PTSD) is a debilitating mental disorder that develops after being exposed to a traumatic event. PTSD is common among adults who have experienced physical/sexual childhood abuse. ... -
Waning effectiveness of COVID-19 vaccines
( Elsevier , 2022 , Article)In The Lancet, Peter Nordström and colleagues1 report the effectiveness of several COVID-19 vaccines and different vaccine schedules against any documented SARS-CoV-2 infection and against severe COVID-19, for up to 9 ... -
Effectiveness of Convalescent Plasma Therapy in COVID-19 Patients with Hematological Malignancies: A Systematic Review
(2022 , Article)Background: Immunocompromised patients, including those with hematological malignancies, are at a high risk of developing severe coronavirus disease 2019 (COVID-19) complications. Currently, there is a limited number of ... -
COVID-19 Vaccine Acceptance among Vulnerable Groups: Syrian Refugees in Jordan
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Despite the wide distribution of COVID-19 vaccines, refugees remain last in line for the intake of vaccines. Syrian refugees in Jordan reach up to 700,000 registered and almost up to 700,000 unregistered refugees. This ... -
Home Cancer Care Research: A Bibliometric and Visualization Analysis (1990–2021)
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Home cancer care research (HCCR) has accelerated, as considerable attention has been placed on reducing cancer-related health costs and enhancing cancer patients’ quality of life. Understanding the current status of HCCR ... -
Effect of Bariatric Surgery on Intima Media Thickness: A Systematic Review and Meta-Analysis
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background: Obesity, and in particular extreme obesity, as a global health problem is an important risk factor for many diseases, including atherosclerotic cardiovascular disease (ACVD). Bariatric surgery might stop or ... -
Diabetes Self-Management and Health-Related Quality of Life among Primary Care Patients with Diabetes in Qatar: A Cross-Sectional Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Diabetes self-management (DSM) practices are an important determinant of health-related outcomes, including health-related quality of life (HRQOL). The purpose of this study is to explore DSM practices and their relationship ... -
Effectiveness of the neutralizing antibody sotrovimab among high-risk patients with mild-to-moderate SARS-CoV-2 in Qatar
( Elsevier , 2022 , Article)ObjectivesTo estimate the real-world effectiveness of sotrovimab against severe, critical, or fatal COVID-19 in Qatar at a time in which most SARS-CoV-2 incidences occurred due to the BA.2 Omicron subvariant. MethodsWe ... -
A cross-sectional study of the impact of COVID-19 pandemic on the physical activity of Jordanian population
( Wiley-Blackwell , 2022 , Article)Background: Since the declaration of the COVID-19 pandemic on 11th March 2020, the public health recommendations have applied lockdowns and restrictions to limit the spread of the disease. These measures determined outdoor ... -
Detection of Antinuclear Antibodies Targeting Intracellular Signal Transduction, Metabolism, Apoptotic Processes and Cell Death in Critical COVID-19 Patients
( Universita Cattolica del Sacro Cuore , 2022 , Article)Background and Objectives: The heterogeneity of the coronavirus disease of 2019 (COVID-19) lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) is a leading ...
