College of Health Sciences: Recent submissions
Now showing items 821-840 of 1696
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Is it the time for Hepatitis E virus (HEV) Testing for Blood Donors in Qatar?
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background: HEV is the etiologic agent of acute hepatitis E. Although HEV usually causes a self-limiting infection, the disease may develop into a chronic or fulminant form of Hepatitis. Sporadic HEV infections spread in ... -
Obesity is associated with the upregulation of TLR4 protein but not associated with polymorphisms of TLR4D299G TLR4T399I
( Hamad bin Khalifa University Press (HBKU Press) , 2018 , Conference Paper)Title: Obesity is associated with the upregulation of TLR4 protein but not associated with polymorphisms of TLR4D299G TLR4T399I.Background: Toll-like-receptor 4 (TLR4) is a pathogen-specific receptor, expressed in white ... -
Performance evaluation of novel fluorescent-based lateral flow immunoassay (LFIA) for rapid detection and quantification of total anti-SARS-CoV-2 S-RBD binding antibodies in infected individuals
( Elsevier , 2022 , Article)The vast majority of the commercially available LFIA is used to detect SARS-CoV-2 antibodies qualitatively. Recently, a novel fluorescence-based LIFA test was developed for quantitative measurement of the total binding ... -
Novel Isosteviol Derivatives Induced Apoptosis In Human Lung Cancer
( Hamad bin Khalifa University Press (HBKU Press) , 2014 , Conference Paper)Background. Cancer metastasis is the major cause of cancer death. We previously reported novel isosteviols derivatives which induced cytotoxicity in lung cancer cells. The understanding of mechanisms which regulate lung ... -
Prevalence of Virulence/Stress Genes in Campylobacter Jejuni from Chicken Meat Sold in Qatari Retail Outlets
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Chicken meat from the shelves of supermarkets in Qatar was tested for the presence of Camplobacter spp., and the presence of five virulence genes (htrB, cdtB, clpB, cadF and ciaB) was assessed in isolates. Forty eight ... -
Gene Expression Profiling and Protein Analysis Reveal Suppression of the C-Myc Oncogene and Inhibition JAK/STAT and PI3K/AKT/mTOR Signaling by Thymoquinone in Acute Myeloid Leukemia Cells
( MDPI , 2022 , Article)Overexpression of c-Myc plays an essential role in leukemogenesis and drug resistance, making c-Myc an attractive target for cancer therapy. However, targeting c-Myc directly is impossible, and c-Myc upstream regulator ... -
The Role of Soluble Adhesion Molecules in Type 2 Diabetes Mellitus
( Hamad bin Khalifa University Press (HBKU Press) , 2018 , Conference Paper)Background: Diabetes mellitus (DM) is a chronic metabolic disorder that is steadily increasing worldwide and is a leading cause of morbidity and mortality. As reported by the World Health Organization (WHO), 346 million ... -
The Effect of Protein Supplementation on Body Muscle Mass and Fat Mass in Qataris PostBariatric Surgery: A Randomized Controlled Trial RCT
( Hamad bin Khalifa University Press (HBKU Press) , 2018 , Conference Paper)Background and objectives: Obesity is a chronic medical condition characterized by an accumulation of excess fat in the body that may lead to negative health consequences. Bariatric surgery has been shown to be the most ... -
Agreement level of vitamin D intake between food frequency questionnaire and 24-h food recall in young Qatari women
( Emerald , 2022 , Article)Purpose – Prevalence of vitamin D insufficiency among young Qatari women is ∼85%. The purpose of the study was to develop a food frequency questionnaire (FFQ) and to assess the degree of agreement between food vitamin D ... -
How does postgraduate diploma in Family Medicine impact on primary care doctors?
( BMC , 2022 , Article)Over the last decade, the emphasis on improving the education and training of family physicians has increased. World Health Organization has also emphasized the importance of a trained primary care workforce. In 2017, ... -
Dietary Diversity in the Eastern Mediterranean Region Before and During the COVID-19 Pandemic: Disparities, Challenges, and Mitigation Measures
( Frontiers Media , 2022 , Article)The COVID-19 pandemic has revealed the Eastern Mediterranean Region's food system's fragility posing severe challenges to maintaining healthy sustainable lifestyle. The aim of this cross-sectional study (N = 13,527 household's ... -
The Special Features of Prenatal and Preimplantation Genetic Counseling in Arab Countries.
( MDPI , 2022 , Article Review)Genetic counseling services have only recently been introduced in most Arab countries, and their utilization is increasing. Prenatal genetic counseling is essential, particularly in the Arab context, which is characterized ... -
Medical Students’ and Trainees’ Country-By-Gender Profiles: Hofstede’s Cultural Dimensions Across Sixteen Diverse Countries
( Frontiers Media , 2022 , Article)Purpose: The global mobility of medical student and trainee populations has drawn researchers’ attention to consider internationalization in medical education. Recently, researchers have focused on cultural diversity, ... -
Description of PTPRG genetic variants identified in a cohort of Chronic Myeloid Leukemia patients and their ability to influence response to Tyrosine kinase Inhibitors
( Elsevier , 2022 , Article)Tyrosine kinase inhibitors (TKIs) have remarkably transformed Ph+ chronic myeloid leukemia (CML) management; however, TKI resistance remains a major clinical challenge. Mutations in BCR-ABL1 are well studied but fail to ... -
Associations with Post-Consultation Health-Status in Primary Care Managed Acute Exacerbation of COPD
( Dove Medical Press , 2022 , Article)Background: It has been demonstrated that antibiotic prescribing for Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) can be safely reduced in primary care when general practitioners have access to ... -
Impact of missing outcome data in meta-analyses of lifestyle interventions during pregnancy to reduce postpartum weight retention: An overview of systematic reviews with meta-analyses and additional sensitivity analyses
( Wiley , 2021 , Article)High risk of bias associated with missing outcome data (MOD) in meta-analyses (MAs) of the effects of lifestyle interventions during pregnancy on postpartum weight retention (PPWR) casts doubt on whether such interventions ... -
Physiological Changes and Interactions Between Microbiome and the Host During Pregnancy
( Frontiers Media , 2022 , Article Review)In recent years, it has become clear that microbiome play a variety of essential roles in human metabolism, immunity, and overall health and that the composition of these microbiome is influenced by our environment, diet, ... -
Preparation, characterization, in vitro drug release and anti-inflammatory of thymoquinone-loaded chitosan nanocomposite
( Elsevier , 2022 , Article)In this study, we formulated Thymoquinone-loaded nanocomposites (TQ-NCs) using high-pressure homogenizer without sodium tripolyphosphate. The TQ-NCs were characterized and their anti-inflammatory determined by the response ... -
QCovSML: A reliable COVID-19 detection system using CBC biomarkers by a stacking machine learning model
( Elsevier , 2022 , Article)The reverse transcription-polymerase chain reaction (RT-PCR) test is considered the current gold standard for the detection of coronavirus disease (COVID-19), although it suffers from some shortcomings, namely comparatively ... -
Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar’s experience
( International Society of Global Health , 2022 , Article)Background: The effective reproduction number, Rt, is a tool to track and understand epidemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset ...