College of Health Sciences: Recent submissions
Now showing items 1161-1180 of 1729
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iTRAQ-based quantitative protein expression profiling and MRM verification of markers in type 2 diabetes.
( American Chemical Society , 2012 , Article)The pathogenesis of Type 2 diabetes mellitus (T2DM) is complex owing to molecular heterogeneity in the afflicted population. Current diagnostic methods rely on blood glucose measurements, which are noninformative with ... -
Integrated datasets of proteomic and metabolomic biomarkers to predict its impacts on comorbidities of type 2 diabetes mellitus
( Dove Medical Press , 2020 , Article)© 2020 Cheema et al. Objective: The objective of the current study is to accomplish a relative exploration of the biological roles of differentially dysregulated genes (DRGs) in type 2 diabetes mellitus (T2DM). The study ... -
Waist Circumference and Risk of Liver Cancer: A Systematic Review and Meta-Analysis of over 2 Million Cohort Study Participants
( Karger Publishers Open Access , 2020 , Article)Liver cancer is the sixth most common type of cancer worldwide, and waist circumference (WC) is associated with its risk beyond body mass index (BMI). This dose-response meta-analysis was performed to investigate the ... -
Fat intake and the risk of coronary heart disease among Jordanians
( Aula Médica Ediciones , 2020 , Article)Introduction: dietary fat has been reported as one of the significant risk factors in the development of cardiovascular diseases (CVD). Objective: this study aimed at assessing the possible association between fat intake ... -
Barriers and Motivators of Appropriate Antibiotic Prescription at PHCC in Qatar: Perspective of Physicians and Pharmacists
( Ministry of Public Health , 2020 , Conference Paper)Antimicrobial resistance (AMR) is a serious public health problem of global concern. The Ministry of Public Health (MOPH) developed the NAP (National Action Plan) to combat AMR in Qatar in collaboration with WHO/EMRO. ... -
Exploring risk factors of diarrheal diseases from male workers’ perspectives in Qatar: A qualitative approach.
( Ministry of Public Health , 2019 , Conference Paper)Background: According to WHO, diarrhea is an infection in the intestinal tract, which can be caused by a variety of bacterial, viral and parasitic organisms. The infection spreads through contaminated food or drinking ... -
Enzyme therapy: a forerunner in catalyzing a healthy society?
( Taylor & Francis , 2020 , Article)The use of enzymes in various industries has been prevalent for centuries. However, their potency as therapeutics remained latent until the late 1950 s, when scientists finally realized the gold mine they were sitting on. ... -
CD44 mediates stem cell mobilization to damaged lung via its novel transcriptional targets, Cortactin and Survivin
( Ivyspring International Publisher , 2020 , Article)Beyond their role in bone and lung homeostasis, mesenchymal stem cells (MSCs) are becoming popular in cell therapy. Various insults may disrupt the repair mechanisms involving MSCs. One such insult is smoking, which is a ... -
Obesity is associated with depression in Malaysian schoolchildren: A cross-sectional study
( Universitas Indonesia , 2020 , Article)Background: Overweight and obesity, which may lead to depression, have become prevalent among children worldwide. Hence, this study aimed to measure obesity and depression among schoolchildren in Kuantan. Methods: This ... -
Prevalence and Predictors of Insulin Resistance in Non-Obese Healthy Young Females in Qatar
( MDPI , 2020 , Article)The state of Qatar suffers from diabetes epidemic due to obesity-associated metabolic syndrome. However, the prevalence of insulin resistance prior to obesity, which could play an important role in the high prevalence of ... -
Short-term improvements in diet quality in people newly diagnosed with type 2 diabetes are associated with smoking status, physical activity and body mass index: the 3D case series study.
( Springer Nature , 2020 , Article)Dietary intake impacts glycaemic control through its effect on weight and glucose-insulin homeostasis. Early glycaemic control is associated with improved outcomes and reduced mortality for people with type 2 diabetes ... -
Global incidence of Necrotizing Enterocolitis: a systematic review and Meta-analysis
( BMC , 2020 , Article)Background: Necrotizing Enterocolitis (NEC) is a major cause of morbidity and mortality in the Neonatal Intensive Care Unit (NICU), yet the global incidence of NEC has not been systematically evaluated. We conducted a ... -
New markers for the detection of polycystic ovary syndrome
( MedCrave Group , 2019 , Article)Polycystic Ovary Syndrome (PCOS) is a highly prevalent, complex genetic disorder of the endocrine system in women. Alterations that occur in women with PCOS can be due to several predisposing factors; among these contributors ... -
Association of Urinary Vitamin D-binding Protein and Megalin as Biomarkers for Diabetic Nephropathy in Type 2 Diabetes Mellitus in Qatari Patients
( OMICS , 2019 , Article)Abstract Background: Nephropathy is a common complication of type 2 diabetes mellitus (T2DM). Previous studies revealed that T2DM patients with nephropathy have higher concentrations of urinary Vitamin D Binding ... -
Association between Genetic Variants of GC Gene at 4q13.3 and Vitamin D Concentrations in Adult Females
( Longdom , 2019 , Article)Background: Vitamin D binding protein, encoded by the GC gene (on 4q13.3), plays an important role in transporting vitamin D. Several Genome-Wide Association Studies (GWASs) have established a significant association ... -
Neutrophil Gelatinase Associated Lipocalin: Is not an Early Marker Inductor for Diabetic Nephropathy in Qatari Population
( BJSTR , 2019 , Article)Background: The WHO Global Report on Diabetes (2016) showed that the number of diabetic patients quadrupled between 1980 and 2016, while causing the death of 1.5 million people. While the global prevalence of diabetes ... -
Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
( MDPI , 2020 , Article Review)Vitamin D and its active metabolites are important nutrients for human skeletal health. UV irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the liver and kidneys into its active form, ... -
Rehabilitation needs in individuals with knee OA in rural Western Cape, South Africa: an exploratory qualitative study
( Cambridge University Press , 2020 , Article)Background: Current clinical practice guidelines have suggested that each individual with knee osteoarthritis (OA) should receive three core treatments from their health care provider. These core treatments comprise of ... -
Muscle Strength and Glycaemic Control among Patients with Type 2 Diabetes.
( MDPI , 2020 , Article)Poor glycaemic control is associated with chronic life-threatening complications. This cross-sectional study examined whether there is an association between handgrip strength and glycaemic control among patients with ... -
Serum vitamin D is associated with improved lung function markers but not with prevalence of asthma, emphysema, and chronic bronchitis
( Nature Research , 2020 , Article)Hypovitaminosis D has been linked to several non-bone diseases. Relation between 25-hydroxyvitamin D [25(OH)D] and lung function and lung diseases has received little attention at the global level. Cross-sectional data ...
