Browsing Biomedical Sciences by Author "Kashyap, Manoj Kumar"
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Analysis of signaling cascades from myeloma cells treated with pristimerin
Almaghrbi, Heba; Elkardawy, Rehab; Kumar. S, Udhaya; Kuttikrishnan, Shilpa; Abunada, Taghreed; Kashyap, Manoj Kumar; Ahmad, Aamir; Uddin, Shahab; Doss. C, George Priya; Zayed, Hatem... more authors ... less authors ( Elsevier , 2022 , Book chapter)Multiple myeloma (MM) is the 2nd most frequently diagnosed blood cancer after non-Hodgkin's lymphoma. The present study aimed to identify the differentially expressed genes (DEGs) between the control and pristimerin-treated ... -
Integrative ontology and pathway-based approach identifies distinct molecular signatures in transcriptomes of esophageal squamous cell carcinoma
Udhaya Kumar, S.; Balasundaram, Ambritha; Anu Preethi, V.; Chatterjee, Sayoni; Kameshwari Gollakota, G.V.; Kashyap, Manoj Kumar; George Priya Doss, C.; Zayed, Hatem... more authors ... less authors ( Elsevier , 2022 , Book chapter)Esophageal squamous cell carcinoma (ESCC) remains a serious concern globally due to many factors that including late diagnosis, lack of an ideal biomarker for diagnosis and prognosis, and high rate of mortality. In this ... -
RNA splicing: a dual-edged sword for hepatocellular carcinoma
Kashyap, Anjali; Tripathi, Greesham; Tripathi, Avantika; Rao, Rashmi; Kashyap, Manju; Bhat, Anjali; Kumar, Deepak; Rajhans, Anjali; Kumar, Pravindra; Chandrashekar, Darshan Shimoga; Mahmood, Riaz; Husain, Amjad; Zayed, Hatem; Bharti, Alok Chandra; Kashyap, Manoj Kumar... more authors ... less authors ( Springer , 2022 , Article Review)RNA splicing is the fundamental process that brings diversity at the transcriptome and proteome levels. The spliceosome complex regulates minor and major processes of RNA splicing. Aberrant regulation is often associated ... -
Tumor reversion: a dream or a reality.
Tripathi, Avantika; Kashyap, Anjali; Tripathi, Greesham; Yadav, Joni; Bibban, Rakhi; Aggarwal, Nikita; Thakur, Kulbhushan; Chhokar, Arun; Jadli, Mohit; Sah, Ashok Kumar; Verma, Yeshvandra; Zayed, Hatem; Husain, Amjad; Bharti, Alok Chandra; Kashyap, Manoj Kumar... more authors ... less authors ( Pubmed , 2021 , Article)Reversion of tumor to a normal differentiated cell once considered a dream is now at the brink of becoming a reality. Different layers of molecules/events such as microRNAs, transcription factors, alternative RNA splicing, ...