Browsing Biomedical Sciences by Author "Zaghlool, Shaza B"
Now showing items 1-2 of 2
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Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects.
Zaghlool, Shaza B; Al-Shafai, Mashael; Al Muftah, Wadha A; Kumar, Pankaj; Gieger, Christian; Waldenberger, Melanie; Falchi, Mario; Suhre, Karsten... more authors ... less authors ( BioMed Central , 2016 , Article)Environmentally influenced phenotypes, such as obesity and insulin resistance, can be transmitted over multiple generations. Epigenetic modifications, such as methylation of DNA cytosine-guanine (CpG) pairs, may be carriers ... -
PopPAnTe: population and pedigree association testing for quantitative data.
Visconti, Alessia; Al-Shafai, Mashael; Al Muftah, Wadha A; Zaghlool, Shaza B; Mangino, Massimo; Suhre, Karsten; Falchi, Mario... more authors ... less authors ( BioMed Central , 2017 , Article)Family-based designs, from twin studies to isolated populations with their complex genealogical data, are a valuable resource for genetic studies of heritable molecular biomarkers. Existing software for family-based studies ...