تصفح Biomedical Sciences حسب المؤلف "Yassine, Hadi M."
-
Addressing bias in the definition of SARS-CoV-2 reinfection: implications for underestimation
Chemaitelly, Hiam; Ayoub, Houssein H.; Tang, Patrick; Yassine, Hadi M.; Al Thani, Asmaa A.; Hasan, Mohammad R.; Coyle, Peter; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A.; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors ( Frontiers Media , 2024 , Article)Introduction: Reinfections are increasingly becoming a feature in the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, accurately defining reinfection poses methodological ... -
Analytic comparison between three high-throughput commercial SARS-CoV-2 antibody assays reveals minor discrepancies in a high-incidence population
Nasrallah, Gheyath K; Dargham, Soha R; Shurrab, Farah; Al-Sadeq, Duaa W; Al-Jighefee, Hadeel; Chemaitelly, Hiam; Al Kanaani, Zaina; Al Khal, Abdullatif; Al Kuwari, Einas; Coyle, Peter; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Rahim, Hanan F Abdul; Yassine, Hadi M; Al Kuwari, Mohamed G; Qotba, Hamda; Al Romaihi, Hamad Eid; Tang, Patrick; Bertollini, Roberto; Al-Thani, Mohamed H; Althani, Asmaa A; Abu-Raddad, Laith J... more authors ... less authors ( Nature Research , 2021 , Article)Performance of three automated commercial serological IgG-based assays was investigated for assessing SARS-CoV-2 "ever" (past or current) infection in a population-based sample in a high exposure setting. PCR and serological ... -
Antibody-Dependent Enhancement (ADE) and the role of complement system in disease pathogenesis
Thomas, Swapna; Smatti, Maria K.; Ouhtit, Allal; Cyprian, Farhan S.; Almaslamani, Muna A.; Al Thani, Asmaa; Yassine, Hadi M.... more authors ... less authors ( Elsevier Ltd , 2022 , Article Review)Antibody-dependent enhancement (ADE) has been associated with severe disease outcomes in several viral infections, including respiratory infections. In vitro and in vivo studies showed that antibody-response to SARS-CoV ... -
Antimicrobial Resistance of Commensal Escherichia coli Isolated from Food Animals in Qatar
Alhababi, Dalal A; Eltai, Nahla O; Nasrallah, Gheyath K; Farg, Elmoubasher A; Al Thani, Asmaa A; Yassine, Hadi M... more authors ... less authors ( Mary Ann Liebert , 2020 , Article)This study aims at evaluating the phenotypic and genotypic antimicrobial resistance (AMR) patterns of 18 clinically relevant antibiotics in food animals in Qatar. Fecal samples from camels, cattle, and pigeons (300) were ... -
Association of Prior SARS-CoV-2 Infection With Risk of Breakthrough Infection Following mRNA Vaccination in Qatar.
Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; Yassine, Hadi M; Benslimane, Fatiha M; Al Khatib, Hebah A; Tang, Patrick; Hasan, Mohammad R; Coyle, Peter; Al Kanaani, Zaina; Al Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F; Nasrallah, Gheyath K; Al Kuwari, Mohamed Ghaith; Butt, Adeel A; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al Khal, Abdullatif; Bertollini, Roberto... more authors ... less authors ( American Medical Association , 2021 , Article)The effect of prior SARS-CoV-2 infection on vaccine protection remains poorly understood. To assess protection from SARS-CoV-2 breakthrough infection after mRNA vaccination among persons with vs without prior SARS-CoV-2 ... -
Associations of Vaccination and of Prior Infection with Positive PCR Test Results for SARS-CoV-2 in Airline Passengers Arriving in Qatar
Bertollini, Roberto; Chemaitelly, Hiam; Yassine, Hadi M.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Abu-Raddad, Laith J.... more authors ... less authors ( American Medical Association , 2021 , Other)The SARS-CoV-2 pandemic has severely affected international travel. With efficacious COVID-19 vaccines available, Qatar implemented a pilot program between February 18 and April 26, 2021, to ease travel restrictions by ... -
Biological Properties of SARS-CoV-2 Variants: Epidemiological Impact and Clinical Consequences
Hoteit, R.; Hoteit, Reem; Yassine, Hadi M. ( MDPI , 2022 , Article Review)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus that belongs to the coronavirus family and is the cause of coronavirus disease 2019 (COVID-19). As of May 2022, it had caused more than 500 million ... -
Bivalent mRNA-1273.214 vaccine effectiveness against SARS-CoV-2 omicron XBB* infections
Chemaitelly, Hiam; Ayoub, Houssein H.; AlMukdad, Sawsan; Faust, Jeremy S.; Tang, Patrick; Coyle, Peter; Yassine, Hadi M.; Al Thani, Asmaa A.; Al-Khatib, Hebah A.; Hasan, Mohammad R.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H.; Latif, Ali N.; Shaik, Riyazuddin M.; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed G.; Butt, Adeel A.; Al-Romaihi, Hamad E.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors (2023 , Article)In October of 2022, Qatar introduced COVID-19 bivalent vaccination for persons ≥ 12 years using the 50-μg mRNA-1273.214 vaccine combining SARS-CoV-2 ancestral and omicron BA.1 strains.1 We estimated this vaccine’s effectiveness ... -
BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 Delta variant in Qatar.
Tang, Patrick; Hasan, Mohammad R; Chemaitelly, Hiam; Yassine, Hadi M; Benslimane, Fatiha M; Al Khatib, Hebah A; AlMukdad, Sawsan; Coyle, Peter; Ayoub, Houssein H; Al Kanaani, Zaina; Al Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F; Nasrallah, Gheyath K; Al Kuwari, Mohamed Ghaith; Al Romaihi, Hamad Eid; Butt, Adeel A; Al-Thani, Mohamed H; Al Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Nature Researc , 2021 , Article)With the global expansion of the highly transmissible SARS-CoV-2 Delta (B.1.617.2) variant, we conducted a matched test-negative case-control study to assess the real-world effectiveness of COVID-19 messenger RNA vaccines ... -
BNT162b2 antigen dose and SARS-CoV-2 omicron infection in adolescents
Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; Al Thani, Asmaa A.; Al-Khatib, Hebah A.; Hasan, Mohammad R.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed Ghaith; Al-Romaihi, Hamad Eid; Butt, Adeel A.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors ( Elsevier , 2023 , Other)COVID-19 vaccine antigen dose might affect protection against SARS-CoV-2 infection,1, 2 but direct evidence to quantify this effect is absent. We conducted a matched, retrospective, cohort study using a regression ... -
Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
Swapna, Thomas; Ouhtit, Allal; Al Khatib, Hebah A.; Eid, Ali H.; Mathew, Shilu; Nasrallah, Gheyath K.; Emara, Mohamed M.; Al Maslamani, Muna A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier , 2022 , Article Review)Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and type 2 diabetes has increased rapidly and has become one of the leading ... -
Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays.
Ismail, Ahmed; Shurrab, Farah M; Al-Jighefee, Hadeel T; Al-Sadeq, Duaa W; Qotba, Hamda; Al-Shaar, Ibrahim Abdu; Yassine, Hadi M; Abu-Raddad, Laith J; Nasrallah, Gheyath K... more authors ... less authors ( IMR , 2021 , Article)Background: High-throughput assays that can infer neutralizing activity against SARS-CoV-2 are of great importance for assessing the immunity induced by natural infection and COVID-19 vaccines. We aimed to evaluate the ... -
Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2
Younes, Nadin; Al-Sadeq, Duaa W; Al-Jighefee, Hadeel; Younes, Salma; Al-Jamal, Ola; Daas, Hanin I; Yassine, Hadi M; Nasrallah, Gheyath K... more authors ... less authors ( MDPI , 2020 , Article)The recent outbreak of the Coronavirus disease 2019 (COVID-19) has quickly spread worldwide since its discovery in Wuhan city, China in December 2019. A comprehensive strategy, including surveillance, diagnostics, research, ... -
Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar's experience
Bsat, Raghid; Chemaitelly, Hiam; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R.; Kanaani, Zaina Al; Kuwari, Einas Al; Butt, Adeel A.; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Nasrallah, Gheyath K.; Benslimane, Fatiha M.; Khatib, Hebah A.Al; Yassine, Hadi M.; Kuwari, Mohamed G.Al; Romaihi, Hamad Eid Al; Al-Thani, Mohamed H.; Khal, Abdullatif Al; Bertollini, Roberto; Abu-Raddad, Laith J.; Ayoub, Houssein H.... more authors ... less authors ( Edinburgh University Global Health Society , 2022 , Article)Background The effective reproduction number, Rt, is a tool to track and understand pandemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset of ... -
Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar’s experience
Bsat, Raghid; Chemaitelly, Hiam; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R; Al Kanaani, Zaina; Al Kuwari, Einas; Butt, Adeel A; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Nasrallah, Gheyath K; Benslimane, Fatiha M; Al Khatib, Hebah A; Yassine, Hadi M; Al Kuwari, Mohamed G; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al Kha, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J; Ayoub, Houssein H... more authors ... less authors ( International Society of Global Health , 2022 , Article)Background: The effective reproduction number, Rt, is a tool to track and understand epidemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset ... -
Comparative analysis of within-host diversity among vaccinated COVID-19 patients infected with different SARS-CoV-2 variants
Hebah A., Al-Khatib; Smatti, Maria K.; Ali, Fatma H.; Zedan, Hadeel T.; Thomas, Swapna; Ahmed, Muna N.; El-kahlout, Reham A.; Al Bader, Mashael A.; Elgakhlab, Dina; Coyle, Peter V.; Abu-Raddad, Laith J.; Al Thani, Asma A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier , 2022 , Article)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly evolving RNA virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the within-host diversity among vaccinated and ... -
Comparison of antibody immune responses between BNT162b2 and mRNA-1273 SARS-CoV-2 vaccines in naïve and previously infected individuals.
Al-Sadeq, Duaa W; Shurrab, Farah M; Ismail, Ahmed; Amanullah, Fathima Humaira; Thomas, Swapna; Aldewik, Nader; Yassine, Hadi M; Abdul Rahim, Hanan F; Abu-Raddad, Laith; Nasrallah, Gheyath K... more authors ... less authors ( Oxford University Press , 2021 , Article)Two mRNA vaccines, Pfizer-BNT162b2 and Moderna-mRNA-1273, obtained the Emergency Use Listing by WHO for preventing COVID-19. However, little is known about the difference in antibody responses induced by these two mRNA ... -
Computational screening of known broad-spectrum antiviral small organic molecules for potential influenza HA stem inhibitors.
Mathew, Shilu; Al Thani, Asmaa A; Yassine, Hadi M ( Public Library of Science , 2018 , Article)With the emergence of new influenza virus strains that are resistant to current inhibitors such as oseltamivir (anti-neuraminidase (NA)) and amantadine (anti-M2 proton channel), influenza A viruses continue to be a serious ... -
Coronavirus Disease 2019 Disease Severity in Children Infected With the Omicron Variant
Butt, A.A.; Butt, Adeel A.; Dargham, Soha R.; Loka, Srusvin; Shaik, Riyazuddin M.; Chemaitelly, Hiam; Tang, Patrick; Hasan, Mohammad R.; Coyle, Peter V.; Yassine, Hadi M.; Al-Khatib, Hebah A.; Smatti, Maria K.; Kaleeckal, Anvar H.; Latif, Ali Nizar; Zaqout, Ahmed; Almaslamani, Muna A.; Al Khal, Abdullatif; Bertollini, Roberto; Abou-Samra, Abdul Badi; Abu-Raddad, Laith J.... more authors ... less authors ( NLM (Medline) , 2022 , Article)SHORT SUMMARY: Severe acute respiratory syndrome coronavirus 2 infection from the Omicron variant in children/adolescents is less severe than infection from the Delta variant. Those 6 to <18 years also have less severe ... -
The Current Status of Cytomegalovirus (CMV) Prevalence in the MENA region: a systematic review
Al Mana, Hassan; Yassine, Hadi M.; Youne, Nadin N.; Al-Mohannadi, Anjud; Al-Sadeq, Duaa W.; Alhababi, Dalal; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2019 , Article)Human cytomegalovirus (CMV) is a highly prevalent herpesvirus worldwide. According to the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), CMV infects people of all ages, and by ...