تصفح Biomedical Sciences حسب المؤلف "Yalcin, Huseyin"
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Development and In Vivo Testing of Smart Nanoparticles for Enhanced Anti-Cancer Activity and Reduced Cardiotoxicity Associated with Tyrosine Kinase Inhibitors
Yalcin, Huseyin; Al-Thani, Hissa; Shurbaji, Samar ( Qatar University Press , 2021 , Poster)Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One TKI ... -
Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model
Yalcin, Huseyin; Da'As, Sahar; Mohammed, Iman; Nasrallah, Gheyath; Al Suwaidi, Jasim; Yacoub, Magdi... more authors ... less authors ( Qscience. , 2016 , Conference Paper)Hypertrophic cardiomyopathy (HCM) is a serious heart disease and is defined as abnormal left ventricular (LV) wall thickening with diastolic dysfunction. HCM is an autosomal dominant monogenic disease caused by a mutation ...