Biomedical Sciences: المرسلات الحديثة
السجلات المعروضة 81 -- 100 من 763
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Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Background: Resting electrocardiogram (ECG) is a valuable non-invasive diagnostic tool used in clinical medicine to assess the electrical activity of the heart while the patient is resting. Abnormalities in ECG may be ... -
ChatGPT’s scorecard after the performance in a series of tests conducted at the multi-country level: A pattern of responses of generative artificial intelligence or large language models
( Elsevier , 2024 , Article)Recently, researchers have shown concern about the ChatGPT-derived answers. Here, we conducted a series of tests using ChatGPT by individual researcher at multi-country level to understand the pattern of its answer accuracy, ... -
Development of Recombinant PLC-Zeta Protein as a Therapeutic Intervention for the Clinical Treatment of Oocyte Activation Failure
( MDPI , 2024 , Article)The sperm-specific phospholipase C zeta (PLCζ) protein is widely considered as the predominant physiological stimulus for initiating the Ca2+ release responsible for oocyte activation during mammalian fertilization. The ... -
Genetic Susceptibility to Arrhythmia Phenotypes in a Middle Eastern Cohort of 14,259 Whole-Genome Sequenced Individuals
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Background: The current study explores the genetic underpinnings of cardiac arrhythmia phenotypes within Middle Eastern populations, which are under-represented in genomic medicine research. Methods: Whole-genome sequencing ... -
SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines
( Wiley , 2024 , Article)Neutralizing antibodies (NAbs) are elicited after infection and vaccination and have been well studied. However, their antibody-dependent cellular cytotoxicity (ADCC) functionality is still poorly characterized. Here, we ... -
Leprosy: Comprehensive insights into pathology, immunology, and cutting-edge treatment strategies, integrating nanoparticles and ethnomedicinal plants
( Frontiers Media , 2024 , Article Review)Mycobacterium leprae is the causative agent responsible for the chronic disease known as leprosy. This condition is characterized by dermal involvement, often leading to peripheral nerve damage, sensory-motor loss, and ... -
Effectiveness of two and three doses of COVID-19 mRNA vaccines against infection, symptoms, and severity in the pre-omicron era: A time-dependent gradient
( Elsevier , 2024 , Article)BackgroundVaccines were developed and deployed to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed to characterize patterns in the protection provided by the BNT162b2 and ... -
Pathogenic Homocystinuria-Associated T236N Mutation Dramatically Alters the Biochemical Properties of Cystathionine Beta-Synthase Protein
( MDPI , 2024 , Article)Background: Cystathione beta-synthase (CBS) T236N is a novel mutation associated with pyridoxine non-responsiveness, which presents a significant difficulty in the medical treatment of homocystinuria. Reported severe ... -
Follow-Up and Comparative Assessment of SARS-CoV-2 IgA, IgG, Neutralizing, and Total Antibody Responses After BNT162b2 or mRNA-1273 Heterologous Booster Vaccination
( Wiley , 2024 , Article)Background: Priming with ChAdOx1 followed by heterologous boosting is considered in several countries. Nevertheless, analyses comparing the immunogenicity of heterologous booster to homologous primary vaccination regimens ... -
Interleukin-28 and hepatitis C virus genotype-4: Treatmentinduced clearance and liver fibrosis
( Baishideng Publishing Group , 2012 , Article)AIM: To investigate the association between interleukin-28B (IL28B) genotype and response to treatment and hepatic fibrosis in patients with hepatitis C virus (HCV) genotype 4. METHODS: Two hundred and one HCV-genotype 4 ... -
A pilot study on metabolic syndrome and its associated features among Qatari schoolchildren
( Dove Medical Press , 2011 , Article)Aim: This pilot study aimed to evaluate the individual features of the metabolic syndrome (MeS) and its frequency in Qatari schoolchildren aged 6-12 years. Background: MeS has a strong future risk for development of diabetes ... -
The cardiovascular implication of single nucleotide polymorphisms of chromosome 9p21 locus among Arab population
( Wolters Kluwer Health , 2015 , Article)Background: Based on several reports including genome-wide association studies, genetic variability has been linked with higher (nearly half) susceptibility toward coronary artery disease (CAD). We aimed to evaluate the ... -
Erratum: ITRAQ-based Quantitative Protein Expression Profiling and MRM Verification of Markers in Type 2 Diabetes (Journal of Proteome Research (2012) 11 (5527-5537) DOI: 10.1021/pr300798z)
( American Chemical Society (ACS) , 2013 , Article)a Serum samples obtained from individual subjects were analyzed to determine the levels of glucose, Vitamin D among others (as described in methods). The value spreads within the group for each parameter are indicated as ... -
Total and high molecular weight adiponectin in patients with coronary artery disease
( Wolters Kluwer Health , 2009 , Article)BACKGROUND: Serum adiponectin inversely correlates with the extent of coronary artery disease (CAD). OBJECTIVES: To investigate the clinical significance of measuring high molecular weight (HMW) adiponectin in addition to ... -
Addressing bias in the definition of SARS-CoV-2 reinfection: implications for underestimation
( Frontiers Media , 2024 , Article)Introduction: Reinfections are increasingly becoming a feature in the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, accurately defining reinfection poses methodological ... -
Prevalence of hepatitis B and C viruses among migrant workers in Qatar.
( Springer Nature , 2024 , Article)Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft ... -
Antibody-dependent enhancement (ADE) of SARS-CoV-2 in patients exposed to MERS-CoV and SARS-CoV-2 antigens
( Wiley , 2024 , Article)This study evaluated the potential for antibody-dependent enhancement (ADE) in serum samples from patients exposed to Middle East respiratory syndrome coronavirus (MERS-CoV). Furthermore, we evaluated the effect of severe ... -
Elevated serum leptin levels in patients with acute myocardial infarction; Correlation with coronary angiographic and echocardiographic findings
( Springer Nature , 2012 , Article)Background: To assess the relationship between serial serum leptin levels in patients with acute myocardial infarction (AMI) who received thrombolysis and the degree of coronary atherosclerosis, coronary reperfusion, ... -
Hypoadiponectinemia in obese and diabetic subjects in the State of Qatar
( Karger , 2008 , Article)Background: Obesity is commonly associated with insulin resistance (IR), and is a common cause of type 2 diabetes. Adiponectin is an adipose tissue protein that enhances insulin sensitivity and has anti-atherogenic properties. ... -
The prevalence of vitamin d deficiency among female college students at Qatar University
( Saudi Arabian Armed Forces Hospital , 2011 , Article)N/A.
