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The Association between Serum LDL Cholesterol and Genetic Variation in Chromosomal Locus 1p13.3 among Coronary Artery Disease Patients
(
Hindawi
, 2015 , Article)
Background. Several polymorphisms of a locus on chromosome 1p13.3 have a significant effect on low-density lipoprotein cholesterol (LDL-C), atherosclerosis, and acute coronary syndrome (ACS). Methods. We aimed to investigate ...
The cardiovascular implication of single nucleotide polymorphisms of chromosome 9p21 locus among Arab population
(
Medknow Publications
, 2015 , Article)
Background: Based on several reports including genome-wide association studies, genetic variability has been linked with higher (nearly half) susceptibility toward coronary artery disease (CAD). We aimed to evaluate the ...
Joint Associations of Activity Energy Expenditure and Sedentary Behaviors with Adolescent's Obesity and Dietary Habits
(
Lipincott, Williams, & Wilkins
, 2014 , Conference Paper)
PURPOSE: Physical inactivity and sedentary behaviors are thought to be independent entities and differently associate with adverse health outcomes. Thus, the aim of this study was to investigate the joint associations of ...
Editorial: State of art and science advances on nutrition and nutrigenetics in nutrition –related non-communicable diseases in Middle East
(
BioMed Central
, 2015 , Article)
(Not Applicable)
A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
(
American Society for Biochemistry and Molecular Biology
, 2015 , Article)
Retinal hyperpermeability and subsequent macular edema is a cardinal feature of early diabetic retinopathy (DR). Here, we investigated the role of bioactive lipid metabolites, in particular 12/15-lipoxygenase (LOX)-derived ...
Production and Determination of Bioavailable Iron in Sorghum and White bean Noodles
(
Enviro Research
, 2014 , Article)
The objective of this study was to find innovative approaches for the production of iron
fortified noodles that are natural and economically feasible. The functional food was produced
using different combinations . The ...
Resting Energy Expenditure in a Controlled Group of Young Arab Females: Correlations with Body Composition and Agreement with Prediction Equations
(
Scientific Research Publishing
, 2013 , Article)
Objectives: To assess correlates of body compositions measures and resting energy expenditure (REE) in young Arab females, and to compare measured REE values with values calculated from REE predictive equations. Methods: ...
Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids
(
Elsevier
, 2015 , Article)
We recently demonstrated that 12/15-lipoxygenase (LOX) derived metabolites, hydroxyeicosatetraenoic acids (HETEs), contribute to diabetic retinopathy (DR) via NADPH oxidase (NOX) and disruption of the balance in retinal ...
Editorial: Novel Targeted Therapy for Lung Cancer
(
OMICS International
, 2015 , Article)
Lung cancer accounts for about 27% of all cancer deaths and considered as the leading cause of cancer-associated death worldwide. Genotype-driven therapeutics is a standard of care for majority of subgroup of NSCLC patients ...
12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
(
Public Library of Science
, 2013 , Article)
The purpose of the current study was to evaluate the effect of 12/15- lipoxygenase (12/15-LOX) metabolites on retinal endothelial cell (REC) barrier function. FITC-dextran flux across the REC monolayers and electrical ...